Xeris Biopharma Holdings, Inc. (XERS) Ownership

NASDAQ: XERSTop holders, insider trades and short interest.

XERS ownership summary

as of October 17, 2026
Institutions
60.6%
of shares outstanding
Insiders
3.03%
of shares outstanding
Shares outstanding
182.3M
Float
176.1M
shares available to trade
Short interest
4.08%
7.2M shares short
Days to cover
2.45
short interest down 10.6% vs prior month
  • Institutions 60.63%
  • Insiders 3.03%
  • Other investors 36.34%

XERS top institutional holders

20 largest
Xeris Biopharma Holdings, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1BlackRock Inc7.97%14.5M$149.8M+1.6M (+12.2%)June 30, 2026
2D. E. Shaw & Co LP4.28%7.8M$80.5M+15,947 (+0.2%)June 30, 2026
3Vanguard Capital Management, LLC4.03%7.3M$75.7M+359,347 (+5.1%)June 30, 2026
4State Street Corp2.64%4.8M$49.7M+163,392 (+3.5%)June 30, 2026
5Geode Capital Management, LLC2.59%4.7M$48.6M+427,554 (+10.0%)June 30, 2026
6Nuveen, LLC2.41%4.4M$45.2M+1.5M (+50.4%)June 30, 2026
7Rosalind Advisors, Inc.1.60%2.9M$30.0M−322,719 (−10.0%)June 30, 2026
8Qube Research & Technologies1.59%2.9M$29.8M−1.2M (−29.7%)June 30, 2026
9Vanguard Portfolio Management, LLC1.44%2.6M$27.1M−39,400 (−1.5%)June 30, 2026
10Wellington Management Company LLP1.30%2.4M$24.4M+193,749 (+8.9%)June 30, 2026
11Morgan Stanley - Brokerage Accounts1.28%2.3M$24.1M−235,558 (−9.2%)June 30, 2026
12Legal & General Group PLC1.10%2.0M$20.8M+104,503 (+5.5%)June 30, 2026
13Armistice Capital, LLC1.07%2.0M$20.2M+48,864 (+2.6%)June 30, 2026
14Two Sigma Investments LLC1.03%1.9M$19.4M−38,699 (−2.0%)June 30, 2026
15Parkman Healthcare Partners LLC0.99%1.8M$18.6M+86,357 (+5.0%)June 30, 2026
16Algert Global LLC0.96%1.7M$18.0M+585,984 (+50.6%)June 30, 2026
17Northern Trust Corp0.88%1.6M$16.5M+153,132 (+10.6%)June 30, 2026
18The Goldman Sachs Group Inc0.87%1.6M$16.4M−19,578 (−1.2%)June 30, 2026
19AQR Capital Management LLC0.85%1.5M$15.9M+146,609 (+10.5%)June 30, 2026
20Charles Schwab Investment Management Inc0.82%1.5M$15.4M+132,710 (+9.8%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 14 holders added 5.5M shares and 6 cut 1.9M.

XERS top mutual fund and ETF holders

20 largest
Xeris Biopharma Holdings, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.85%5.2M$53.5M—August 31, 2026
2iShares Russell 2000 ETF2.42%4.4M$45.5M−50,880 (−1.1%)September 30, 2026
3CREF Total Global Stock Account R31.12%2.1M$21.1M+98,908 (+5.1%)July 31, 2026
4Fidelity Small Cap Index1.02%1.9M$19.3M+18,158 (+1.0%)July 31, 2026
5iShares Russell 2000 Growth ETF0.88%1.6M$16.5M−2,020 (−0.1%)September 30, 2026
6State Street® SPDR® S&P® PhrmctlsETF0.74%1.4M$13.9M−16,786 (−1.2%)September 30, 2026
7Nuveen Quant Small Cap Equity R60.66%1.2M$12.4M—August 31, 2026
8Vanguard Russell 2000 ETF0.54%986K$10.2M+23,724 (+2.5%)August 31, 2026
9First Trust Small Cap Gr AlphaDEX® ETF0.53%972K$10.0M+1,716 (+0.2%)September 30, 2026
10Schwab US Small-Cap ETF™0.53%966K$10.0M+648 (+0.1%)September 30, 2026
11Fidelity Enhanced Small Cap Core ETF0.50%920K$9.5M+1,929 (+0.2%)September 30, 2026
12Fidelity Extended Market Index0.47%855K$8.8M−13,366 (−1.5%)August 31, 2026
13Nuveen Quant Small/Mid Cap Eq R60.44%797K$8.2M—August 31, 2026
14iShares US Pharmaceuticals ETF0.37%666K$6.9M+2,049 (+0.3%)September 30, 2026
15Federated Hermes MDT Small Cap Core IS0.34%616K$6.3M+383,084 (+164.6%)June 30, 2026
16Janus Henderson Small/Md Cp Gr Alpha ETF0.30%542K$5.6M−105,118 (−16.2%)September 30, 2026
17iShares Micro-Cap ETF0.30%541K$5.6M−3,728 (−0.7%)September 30, 2026
18Vanguard Health Care ETF0.28%515K$5.3M+2,232 (+0.4%)August 31, 2026
19Vanguard Explorer Inv0.27%490K$5.1M—June 30, 2026
20Xtrackers S&P 500 Swap ETF 1C0.26%465K$4.8M−643,048 (−58.0%)December 31, 2025

Funds report holdings monthly or quarterly; dates differ by fund.

XERS insider transactions

latest 17
Xeris Biopharma Holdings, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-04-01Beth HechtSell$5.9916,667$99,835
2026-03-30James Aloysius BradySell$5.5410,834$60,020
2026-03-02Beth HechtSell$6.2516,667$104,169
2026-02-02Beth HechtSell$7.4516,667$124,169
2026-01-08Kevin MccullochSell$8.0015,000$120,000
2026-01-05John Patrick Shannon JrSell$7.0824,907$176,342
2026-01-02Beth HechtSell$7.4316,667$123,836
2025-12-19John JohnsonSell$7.22135,400$977,588
2025-12-12Barbara-Jean A Bormann-KennedySell$7.0915,000$106,350
2025-12-01Beth HechtSell$7.0116,667$116,836
2025-11-13John Patrick Shannon JrSell$7.4623,242$173,385
2025-11-11Beth HechtSell$7.4016,667$123,336
2025-09-11Marla PerskySell$7.7215,500$119,660
2025-08-28Jeffrey W ShermanSell$7.9242,232$334,477
2025-08-13John JohnsonSell$7.32107,500$786,900
2025-08-12Dawn HalkuffSell$7.2842,500$309,400
2025-06-13Kevin MccullochBuy$4.3825,000$109,500

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

XERS shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns XERS

Institutional investors own 60.6% of Xeris Biopharma's shares and insiders 3.03%. The largest holder is BlackRock Inc with 7.97% of the shares (14.5M), as of June 30, 2026. Among the top 20 institutions, 14 added shares and 6 reduced their stake in the latest filings. Short interest is 4.08% of the float, or 2.45 days of average trading volume. The share count rose 3,028.1% since 2016.

Related: XERS analyst forecast, XERS key metrics. See the XERS stock overview for the latest quote and news.

XERS ownership FAQ

Who owns the most Xeris Biopharma stock?

The largest shareholders of Xeris Biopharma are BlackRock Inc (7.97%), D. E. Shaw & Co LP (4.28%), Vanguard Capital Management, LLC (4.03%), State Street Corp (2.64%), Geode Capital Management, LLC (2.59%).

What percentage of Xeris Biopharma is owned by institutions?

Institutions hold 60.6% of Xeris Biopharma's shares outstanding; insiders hold 3.03%.

Which funds own Xeris Biopharma?

The largest fund holders of Xeris Biopharma are Vanguard MStar Total Stk Mkt Idx Invest (2.85%), iShares Russell 2000 ETF (2.42%), CREF Total Global Stock Account R3 (1.12%), Fidelity Small Cap Index (1.02%), iShares Russell 2000 Growth ETF (0.88%).

What is Xeris Biopharma's short interest?

7.2M shares of Xeris Biopharma were sold short, 4.08% of the float; at the average daily volume it would take 2.45 days to cover.

Are insiders buying or selling Xeris Biopharma?

Of the latest 17 reported insider transactions in Xeris Biopharma (since June 13, 2025), 1 were purchases and 16 were sales.

How many shares of Xeris Biopharma are outstanding?

Xeris Biopharma has 182.3M shares outstanding, of which 176.1M are in the public float.

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