Xeris Biopharma Holdings, Inc. (XERS) Key Metrics

NASDAQ: XERSValuation, returns, debt and efficiency ratios over 10 years.

XERS valuation today

Trailing 12 months · as of October 17, 2026
Market cap
$1.88B
Enterprise value
$1.75B
P/E (TTM)
—
Forward P/E
36.9
PEG ratio
—
Price / sales
5.6
10-yr median 2.5
Price / book
107.7
10-yr median 4.0
EV / EBITDA
73.1
Dividend yield
—
Beta
0.84

XERS key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

XERS valuation Price multiples at each fiscal year-end price.

Price / sales+89.6%
4.6
2025 · hover or tap a bar for each year
2021: 4.72022: 1.6 (−65.0%)2023: 2.0 (+20.6%)2024: 2.5 (+24.1%)2025: 4.6 (+89.6%)
20162025
Price / book
99.1
2025 · hover or tap a bar for each year
2021: 2.42022: 4.0 (+64.2%)2025: 99.1
20162025
Free cash flow yield+9.7 pts
2.1%
2025 · hover or tap a bar for each year
2021: −41.7%2022: −57.3% (−15.6 pts)2023: −15.2% (+42.1 pts)2024: −7.6% (+7.6 pts)2025: 2.1% (+9.7 pts)
20162025

XERS valuation history

Fiscal year-endToday10-year median

XERS returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

XERS debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

XERS cash returned to shareholders

DividendsBuybacksFree cash flow

XERS price vs earnings per share

Share price at year-endEPS (right axis)

XERS key metrics

2016–2025
Xeris Biopharma Holdings, Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$1.36B$497.6M$323.5M$180.4M$231.5M—————
Enterprise value$1.28B$697.4M$480.3M$256.5M$217.2M—————
Price / sales4.62.52.01.64.7—————
Price / book99.1——4.02.4—————
Price / free cash flow48.6—————————
Price / operating cash flow47.4—————————
EV / sales4.43.42.92.34.4—————
EV / EBITDA100.9—————————
EV / free cash flow45.9—————————
Earnings yield0.0%−11.0%−19.2%−52.5%−53.0%—————
Free cash flow yield2.1%−7.6%−15.2%−57.3%−41.7%—————
Dividend yield———81.5%10.8%—————
Shareholder yield (dividends + buybacks)0.8%0.8%0.3%81.8%11.1%—————
Share price at fiscal year-end$7.85$3.39$2.35$1.33$2.93$4.92$7.05$17.00——
Per share
Revenue per share$1.69$1.38$1.19$0.81$0.63—————
Earnings per share$0.00−$0.37−$0.45−$0.70−$1.55—————
Operating cash flow per share$0.17−$0.25−$0.34−$0.76−$1.21—————
Free cash flow per share$0.16−$0.26−$0.36−$0.76−$1.22—————
Cash per share$0.64$0.49$0.53$0.90$1.30—————
Book value per share$0.08−$0.20−$0.05$0.33$1.21—————
Tangible book value per share−$0.56−$1.03−$1.01−$0.72−$0.75—————
Dividends per share———$1.08$0.32—————
Capex per share$0.00$0.01$0.02$0.00$0.01—————
Debt per share$0.22$1.85$1.66$1.46$1.11—————
Shares outstanding172.7M146.8M137.7M135.6M79.0M—————
Change in shares outstanding+17.7%+6.6%+1.5%+71.6%——————
Returns & profitability
Return on equity (ROE)———−134.8%−223.8%−869.9%−279.6%−683.7%——
Return on invested capital (ROIC)—−16.6%−25.6%−64.0%−233.1%—————
Return on assets (ROA)0.2%−17.0%−18.7%−29.2%−59.4%−115.2%−109.7%−72.8%−67.6%−39.4%
Return on tangible assets0.2%−27.2%−32.8%−47.1%−81.8%−115.2%−115.2%−50.1%−59.0%−39.4%
Free cash flow margin9.6%−18.6%−30.1%−93.8%−194.8%—————
Income quality (OCF / net income)51.67—————————
Financial health
Total debt$37.8M$271.4M$229.2M$198.1M$88.1M$58.3M$58.3M$40.1M$2.6M$902,000
Cash & short-term investments$111.0M$71.6M$72.5M$122.0M$102.4M$75.5M$75.5M$112.6M$42.0M$32.3M
Net debt−$73.3M$199.8M$156.7M$76.1M−$14.4M−$17.2M−$17.2M−$72.5M−$39.5M−$31.4M
Debt / equity2.76——4.380.924.044.040.53——
Debt / assets0.100.840.710.570.290.530.530.330.060.03
Net debt / EBITDA−5.77—————————
Current ratio2.191.671.642.541.803.203.2011.599.0613.13
Quick ratio1.571.191.232.201.573.123.1211.599.0613.13
Interest coverage0.9-1.0-1.7-5.8-16.0-17.1-17.1-23.3——
Working capital$130.7M$67.2M$61.1M$113.2M$63.6M$60.1M$60.1M$107.7M$39.2M$30.6M
Invested capital−$59.6M$170.2M$150.0M$121.3M$80.9M−$2.8M−$2.8M$2.9M−$97.3M−$63.3M
Tangible asset value−$97.2M−$151.4M−$139.4M−$98.3M−$59.1M$14.4M$14.4M$75.4M−$57.8M−$31.9M
Net current asset value−$129.5M−$185.0M−$173.1M−$112.5M−$66.5M−$7.1M−$7.1M$73.3M−$58.8M−$32.3M
Graham number$0.08—————————
Graham net-net per share−$1.08−$1.54−$1.51−$1.05−$1.07—————
Capital allocation
Dividends paid———$147.1M$25.1M$95.6M$60.7M———
Share buybacks (net)$10.9M$3.7M$1.0M$468,000$534,000$63,000$4.5M$0$0$0
Dividends + buybacks / free cash flow38.9%—————————
Capex / revenue0.2%0.4%1.4%0.5%2.2%13.9%40.7%61.3%45.0%3.3%
Capex / operating cash flow2.4%—————————
Capex / depreciation0.060.070.170.040.580.261.034.723.950.30
Stock-based compensation / revenue7.7%9.0%6.5%11.0%23.0%303.9%238.2%70.1%32.1%50.2%
R&D / revenue10.7%12.6%13.6%19.0%50.7%2,220.4%2,220.4%1,649.2%1,296.0%952.4%
SG&A / revenue62.5%80.5%89.1%124.9%253.5%2,708.7%2,316.7%856.5%515.1%377.7%
Efficiency
Days sales outstanding57.271.578.079.981.5692.7570.4301.2152.534.3
Days of inventory on hand399.3431.1405.0345.5278.1495.5495.5—0.1—
Days payables outstanding18.368.7103.0109.1199.11,275.8736.512,349.2150,151.959,996.9
Cash conversion cycle (days)438.1434.0380.0316.4160.5-87.6329.4-12,048.0-149,999.3-59,962.6
Receivables turnover6.385.104.684.574.480.530.641.212.3910.64
Payables turnover19.915.323.543.351.830.290.500.030.000.01
Inventory turnover0.910.850.901.061.310.740.74—4,000.00—
Asset turnover0.830.630.490.340.240.020.020.030.040.03
Average receivables$45.7M$39.8M$35.0M$24.1M$11.1M$5.2M$4.3M$2.0M$650,000$101,000
Average payables$2.7M$6.9M$8.1M$6.8M$7.3M$5.6M$3.2M$1.4M$1.6M$1.3M
Average inventory$58.4M$43.5M$31.8M$21.4M$10.1M$2.2M$2.2M—$1—
Intangibles / total assets28.9%37.7%41.1%41.6%50.7%0.0%0.0%0.0%0.0%0.0%

Computed from XERS's annual financial statements (latest annual report filed March 2, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

XERS valuation and financial ratios

It ended the year with $37.8 million of debt and $111.0 million in cash and short-term investments, a net cash position of $73.3 million. It returned $10.9 million to shareholders: $0 in dividends and $10.9 million in share buybacks, 39% of free cash flow.

See the XERS income statement, the XERS chart for price history, or the XERS stock overview for the latest quote and news.

XERS key metrics FAQ

What is Xeris Biopharma's EV/EBITDA?

Xeris Biopharma's enterprise value was 100.9 times EBITDA at the end of fiscal 2025 (enterprise value $1.3 billion, EBITDA $12.7 million); the current EV/EBITDA is 73.1.

How much debt does Xeris Biopharma have?

Xeris Biopharma had total debt of $37.8 million at the end of fiscal 2025, a debt-to-equity ratio of 2.76 and more cash than debt.

Does Xeris Biopharma buy back its shares?

Yes. Xeris Biopharma spent $10.9 million on net share repurchases in fiscal 2025 Shares outstanding changed +17.7% over the year, to 172.7M..

What is Xeris Biopharma's free cash flow yield?

Xeris Biopharma generated $27.9 million of free cash flow in fiscal 2025, a free cash flow yield of 2.1% on its market value at year-end ($1.4 billion).

What is Xeris Biopharma's current ratio?

Xeris Biopharma's current ratio was 2.19 at the end of fiscal 2025: current assets were 2.19 times current liabilities.

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