Arrowhead Pharmaceuticals, Inc. (ARWR) Ownership

NASDAQ: ARWRTop holders, insider trades and short interest.

ARWR ownership summary

as of October 18, 2026
Institutions
85.2%
of shares outstanding
Insiders
3.66%
of shares outstanding
Shares outstanding
141.3M
Float
122.4M
shares available to trade
Short interest
10.60%
10.8M shares short
Days to cover
4.77
short interest up 16.0% vs prior month
  • Institutions 85.25%
  • Insiders 3.66%
  • Other investors 11.10%

ARWR top institutional holders

20 largest
Arrowhead Pharmaceuticals, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1BlackRock Inc10.50%14.8M$829.0M−3.3M (−18.3%)June 30, 2026
2venBio Select Advisor LLC8.04%11.4M$634.8M+655,556 (+6.1%)June 30, 2026
3FMR Inc5.69%8.0M$449.4M+773,152 (+10.6%)June 30, 2026
4Vanguard Portfolio Management, LLC4.50%6.4M$355.0M−794,781 (−11.1%)June 30, 2026
5Vanguard Capital Management, LLC4.33%6.1M$341.6M+78,537 (+1.3%)June 30, 2026
6State Street Corp4.03%5.7M$318.3M−801,490 (−12.3%)June 30, 2026
7NORGES BANK2.76%3.9M$217.8M+2.2M (+128.6%)June 30, 2026
8Amvescap Plc.2.75%3.9M$217.1M+603,329 (+18.4%)June 30, 2026
9Geode Capital Management, LLC2.50%3.5M$197.4M−748,216 (−17.5%)June 30, 2026
10Fred Alger Management, LLC2.34%3.3M$184.6M−40,574 (−1.2%)June 30, 2026
11Baker Bros Advisors LP1.41%2.0M$111.4M—June 30, 2026
12Siren, L.L.C.1.21%1.7M$95.9M+100,000 (+6.2%)June 30, 2026
13Vestal Point Capital LP1.11%1.6M$88.0M−700,000 (−30.8%)June 30, 2026
14HHG PLC1.02%1.4M$80.3M+156,544 (+12.2%)March 31, 2026
15Deerfield Management Co0.98%1.4M$77.6M−184,242 (−11.7%)June 30, 2026
16First Trust Advisors L.P.0.96%1.4M$75.6M+1.2M (+807.1%)June 30, 2026
17Driehaus Capital Management LLC0.96%1.4M$75.5M+160,221 (+13.5%)June 30, 2026
18Jupiter Topco LLC0.86%1.2M$68.3M+1.2M (0.0%)June 30, 2026
19Northern Trust Corp0.84%1.2M$66.7M−462,969 (−28.0%)June 30, 2026
20Dimensional Fund Advisors, Inc.0.84%1.2M$66.1M+573,077 (+94.2%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 11 holders added 7.7M shares and 8 cut 7.1M.

ARWR top mutual fund and ETF holders

20 largest
Arrowhead Pharmaceuticals, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1iShares Core S&P Mid-Cap ETF3.56%5.0M$281.3M−1,800 (−0.0%)September 30, 2026
2Vanguard MStar Total Stk Mkt Idx Invest3.01%4.3M$237.9M−4,734 (−0.1%)August 31, 2026
3Vanguard Small Cap Index2.14%3.0M$168.9M−57,777 (−1.9%)September 30, 2026
4Fidelity Growth Company Fund1.84%2.6M$145.5M+51,300 (+2.0%)August 31, 2026
5State Street® SPDR® S&P® Biotech ETF1.27%1.8M$100.6M−34,250 (−1.9%)September 30, 2026
6Invesco S&P MidCap Momentum ETF1.27%1.8M$100.6M—September 30, 2026
7Vanguard MStar Small Cap Growth Indx Inv1.19%1.7M$94.0M−84,908 (−4.8%)September 30, 2026
8State Street® SPDR® S&P MIDCAP 400® ETF0.74%1.0M$58.4M+14,314 (+1.4%)September 30, 2026
9iShares Biotechnology ETF0.73%1.0M$58.0M−7,856 (−0.8%)September 30, 2026
10Invesco Discovery A0.67%940K$52.5M+46,497 (+5.2%)August 31, 2026
11iShares S&P Mid-Cap 400 Growth ETF0.58%815K$45.6M−870 (−0.1%)September 30, 2026
12Alger Focus Equity I0.54%763K$42.6M−2,676 (−0.3%)July 31, 2026
13State Street SPDR Port S&P 400 Md CpETF0.53%747K$41.7M−1,048 (−0.1%)September 30, 2026
14Fidelity Growth Company K60.53%745K$41.7M+14,600 (+2.0%)August 31, 2026
15Schwab US Small-Cap ETF™0.53%743K$41.6M+495 (+0.1%)September 30, 2026
16Fidelity Extended Market Index0.49%685K$38.3M−6,654 (−1.0%)August 31, 2026
17Fidelity Series Growth Company0.44%618K$34.5M+6,200 (+1.0%)August 31, 2026
18Hood River Small-Cap Growth Instl0.40%572K$32.0M−6,492 (−1.1%)June 30, 2026
19iShares Russell Mid-Cap ETF0.39%558K$31.2M+1,026 (+0.2%)September 30, 2026
20Fidelity Mid Cap Index0.36%514K$28.7M+1,807 (+0.4%)August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

ARWR insider transactions

latest 20
Arrowhead Pharmaceuticals, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-04-23James C HamiltonSell$75.0010,000$750,000
2026-04-22Daniel Joseph ApelSell$71.3513,095$934,328
2026-03-05James C HamiltonSell$64.1910,000$641,900
2026-01-05James C HamiltonSell$63.1140,164$2.5M
2026-01-05Patrick O'brienSell$63.1149,493$3.1M
2026-01-02Christopher Richard AnzaloneSell$66.1013,187$871,661
2025-12-29Christopher Richard AnzaloneSell$69.1351,726$3.6M
2025-12-26Mauro FerrariSell$70.007,530$527,100
2025-12-22Christopher Richard AnzaloneSell$68.4412,586$861,386
2025-12-19Victoria VakienerSell$67.6810,040$679,507
2025-12-19William D WaddillSell$67.658,367$566,028
2025-12-19Christopher Richard AnzaloneSell$67.6613,445$909,689
2025-12-19Adeoye Y OlukotunSell$67.6610,000$676,600
2025-12-17Christopher Richard AnzaloneSell$64.0485,000$5.4M
2025-12-16Christopher Richard AnzaloneSell$62.5854,298$3.4M
2025-12-15Christopher Richard AnzaloneSell$68.85130,000$9.0M
2025-12-05Michael S PerrySell$61.0316,250$991,738
2025-11-28Mauro FerrariSell$56.398,750$493,412
2025-10-01James C HamiltonSell$35.0020,000$700,000
2025-09-12James C HamiltonSell$30.0015,000$450,000

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

ARWR shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns ARWR

Institutional investors own 85.2% of Arrowhead Pharmaceuticals's shares and insiders 3.66%. The largest holder is BlackRock Inc with 10.50% of the shares (14.8M), as of June 30, 2026. Among the top 20 institutions, 11 added shares and 8 reduced their stake in the latest filings. Short interest is 10.60% of the float, or 4.77 days of average trading volume. The share count rose 157.3% since 2014.

Related: ARWR analyst forecast, ARWR key metrics. See the ARWR stock overview for the latest quote and news.

ARWR ownership FAQ

Who owns the most Arrowhead Pharmaceuticals stock?

The largest shareholders of Arrowhead Pharmaceuticals are BlackRock Inc (10.50%), venBio Select Advisor LLC (8.04%), FMR Inc (5.69%), Vanguard Portfolio Management, LLC (4.50%), Vanguard Capital Management, LLC (4.33%).

What percentage of Arrowhead Pharmaceuticals is owned by institutions?

Institutions hold 85.2% of Arrowhead Pharmaceuticals's shares outstanding; insiders hold 3.66%.

Which funds own Arrowhead Pharmaceuticals?

The largest fund holders of Arrowhead Pharmaceuticals are iShares Core S&P Mid-Cap ETF (3.56%), Vanguard MStar Total Stk Mkt Idx Invest (3.01%), Vanguard Small Cap Index (2.14%), Fidelity Growth Company Fund (1.84%), State Street® SPDR® S&P® Biotech ETF (1.27%).

What is Arrowhead Pharmaceuticals's short interest?

10.8M shares of Arrowhead Pharmaceuticals were sold short, 10.60% of the float; at the average daily volume it would take 4.77 days to cover.

Are insiders buying or selling Arrowhead Pharmaceuticals?

Of the latest 20 reported insider transactions in Arrowhead Pharmaceuticals (since September 12, 2025), 0 were purchases and 20 were sales.

How many shares of Arrowhead Pharmaceuticals are outstanding?

Arrowhead Pharmaceuticals has 141.3M shares outstanding, of which 122.4M are in the public float.

Biotechnology: ownership