Vertex Pharmaceuticals Incorporated (VRTX) Ownership
VRTX ownership summary
as of October 18, 2026- Institutions
- 98.2% of shares outstanding
- Insiders
- 0.21% of shares outstanding
- Shares outstanding
- 253.5M
- Float
- 252.7M shares available to trade
- Short interest
- 2.01% 4.5M shares short
- Days to cover
- 4.39 short interest down 4.5% vs prior month
- Institutions 98.22%
- Insiders 0.21%
- Other investors 1.57%
VRTX top institutional holders
20 largest| # | Holder | % of shares | Shares | Value | Change | Reported |
|---|---|---|---|---|---|---|
| 1 | Capital World Investors | 10.30% | 26.1M | $13.05B | +746,890 (+2.9%) | June 30, 2026 |
| 2 | BlackRock Inc | 9.51% | 24.1M | $12.05B | +139,856 (+0.6%) | June 30, 2026 |
| 3 | Capital Research Global Investors | 7.69% | 19.5M | $9.74B | −1.6M (−7.7%) | June 30, 2026 |
| 4 | Vanguard Capital Management, LLC | 6.54% | 16.6M | $8.29B | +67,903 (+0.4%) | June 30, 2026 |
| 5 | State Street Corp | 4.68% | 11.9M | $5.93B | +141,320 (+1.2%) | June 30, 2026 |
| 6 | Amvescap Plc. | 3.17% | 8.0M | $4.02B | +150,441 (+1.9%) | June 30, 2026 |
| 7 | JPMorgan Chase & Co | 2.57% | 6.5M | $3.26B | −515,556 (−7.3%) | June 30, 2026 |
| 8 | Geode Capital Management, LLC | 2.37% | 6.0M | $3.01B | −121,773 (−2.0%) | June 30, 2026 |
| 9 | Vanguard Portfolio Management, LLC | 1.92% | 4.9M | $2.44B | −266,622 (−5.2%) | June 30, 2026 |
| 10 | Capital Research & Mgmt Co - Division 3 | 1.85% | 4.7M | $2.35B | −430,933 (−8.4%) | June 30, 2026 |
| 11 | Loomis, Sayles & Company LP | 1.55% | 3.9M | $1.96B | −82,868 (−2.1%) | June 30, 2026 |
| 12 | Franklin Templeton Inc | 1.32% | 3.3M | $1.67B | +2.8M (+507.3%) | June 30, 2026 |
| 13 | Wellington Management Company LLP | 1.28% | 3.2M | $1.62B | +35,069 (+1.1%) | June 30, 2026 |
| 14 | Morgan Stanley - Brokerage Accounts | 1.28% | 3.2M | $1.62B | +53,258 (+1.7%) | June 30, 2026 |
| 15 | UBS Asset Mgmt Americas Inc | 1.22% | 3.1M | $1.54B | +29,287 (+1.0%) | June 30, 2026 |
| 16 | Bank of America Corp | 1.20% | 3.0M | $1.52B | +160,995 (+5.6%) | June 30, 2026 |
| 17 | AllianceBernstein L.P. | 1.19% | 3.0M | $1.51B | −891,471 (−22.8%) | June 30, 2026 |
| 18 | Jennison Associates LLC | 1.18% | 3.0M | $1.50B | +258,471 (+9.4%) | June 30, 2026 |
| 19 | NORGES BANK | 1.17% | 3.0M | $1.49B | −204,932 (−6.5%) | June 30, 2026 |
| 20 | Ameriprise Financial Inc | 1.03% | 2.6M | $1.30B | −28,659 (−1.1%) | June 30, 2026 |
Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 11 holders added 4.6M shares and 9 cut 4.2M.
VRTX top mutual fund and ETF holders
20 largest| # | Holder | % of shares | Shares | Value | Change | Reported |
|---|---|---|---|---|---|---|
| 1 | American Funds Growth Fd of Amer A | 5.09% | 12.9M | $6.45B | +365,727 (+2.9%) | September 30, 2026 |
| 2 | Vanguard MStar Total Stk Mkt Idx Invest | 3.18% | 8.1M | $4.03B | −15,548 (−0.2%) | August 31, 2026 |
| 3 | Vanguard 500 Index Investor | 2.63% | 6.7M | $3.33B | −88,384 (−1.3%) | September 30, 2026 |
| 4 | American Funds American Balanced A | 2.14% | 5.4M | $2.71B | −129,492 (−2.3%) | September 30, 2026 |
| 5 | Invesco QQQ Trust | 2.09% | 5.3M | $2.65B | −8,624 (−0.2%) | September 30, 2026 |
| 6 | American Funds AMCAP A | 1.87% | 4.7M | $2.37B | +83,023 (+1.8%) | September 30, 2026 |
| 7 | American Funds Invmt Co of Amer A | 1.83% | 4.6M | $2.31B | −1.6M (−26.1%) | September 30, 2026 |
| 8 | American Funds New Perspective A | 1.35% | 3.4M | $1.71B | +50,624 (+1.5%) | September 30, 2026 |
| 9 | iShares Core S&P 500 ETF | 1.33% | 3.4M | $1.69B | −5,439 (−0.2%) | September 30, 2026 |
| 10 | Fidelity 500 Index | 1.30% | 3.3M | $1.65B | +12,654 (+0.4%) | August 31, 2026 |
| 11 | State Street® SPDR® S&P 500® ETF | 1.23% | 3.1M | $1.55B | — | September 30, 2026 |
| 12 | Vanguard MStar Growth Index Investor | 1.10% | 2.8M | $1.40B | +38,042 (+1.4%) | September 30, 2026 |
| 13 | American Funds Cptl Wld Gr&Inc A | 0.94% | 2.4M | $1.19B | +39,105 (+1.7%) | September 30, 2026 |
| 14 | American Funds Washington Mutual A | 0.78% | 2.0M | $987.4M | −275,000 (−12.2%) | September 30, 2026 |
| 15 | Vanguard Health Care Inv | 0.75% | 1.9M | $944.6M | +261,561 (+16.1%) | June 30, 2026 |
| 16 | State Street®HlthCrSelSectSPDR®ETF | 0.71% | 1.8M | $898.2M | +5,584 (+0.3%) | September 30, 2026 |
| 17 | American Funds IS® Growth 1 | 0.69% | 1.7M | $872.7M | +105,396 (+6.4%) | September 30, 2026 |
| 18 | Putnam Large Cap Value A | 0.66% | 1.7M | $833.1M | — | August 31, 2026 |
| 19 | iShares Biotechnology ETF | 0.64% | 1.6M | $809.1M | −12,264 (−0.8%) | September 30, 2026 |
| 20 | American Funds New Economy A | 0.64% | 1.6M | $808.9M | — | September 30, 2026 |
Funds report holdings monthly or quarterly; dates differ by fund.
VRTX insider transactions
latest 20| Date | Name | Transaction | Price | Shares | Value |
|---|---|---|---|---|---|
| 2026-04-01 | Joy Liu | Sell | $449.17 | 978 | $439,288 |
| 2026-03-13 | Carmen Bozic | Sell | $481.79 | 2,329 | $1.1M |
| 2026-02-25 | Amit Sachdev | Sell | $486.35 | 1,846 | $897,802 |
| 2026-02-25 | Duncan Mckechnie | Sell | $487.65 | 4,910 | $2.4M |
| 2026-02-25 | Edward Morrow Atkinson III | Sell | $486.35 | 668 | $324,882 |
| 2026-02-25 | Jonathan Biller | Sell | $486.35 | 945 | $459,601 |
| 2026-02-25 | Kristen Ambrose | Sell | $486.35 | 223 | $108,456 |
| 2026-02-25 | Mark E Bunnage | Sell | $486.35 | 620 | $301,537 |
| 2026-02-25 | Ourania Tatsis | Sell | $486.35 | 260 | $126,451 |
| 2026-02-19 | Amit Sachdev | Sell | $468.83 | 58,613 | $27.5M |
| 2026-02-13 | Ourania Tatsis | Sell | $499.99 | 1,500 | $749,985 |
| 2026-02-11 | Mark E Bunnage | Sell | $460.43 | 2,021 | $930,529 |
| 2026-02-11 | Ourania Tatsis | Sell | $460.43 | 466 | $214,560 |
| 2026-02-11 | Kristen Ambrose | Sell | $460.43 | 1,376 | $633,552 |
| 2026-02-11 | Jonathan Biller | Sell | $460.43 | 1,925 | $886,328 |
| 2026-02-11 | Edward Morrow Atkinson III | Sell | $460.43 | 1,751 | $806,213 |
| 2026-01-29 | David Taylor | Sell | $475.68 | — | — |
| 2026-01-07 | Ourania Tatsis | Sell | $474.99 | 4,500 | $2.1M |
| 2026-01-06 | Charles F Wagner Jr | Sell | $461.00 | 9,532 | $4.4M |
| 2025-12-03 | Charles F Wagner Jr | Sell | $456.00 | 14,000 | $6.4M |
Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.
VRTX shares outstanding
Year-end shares outstanding, adjusted for splits.
Who owns VRTX
Institutional investors own 98.2% of Vertex's shares and insiders 0.21%. The largest holder is Capital World Investors with 10.30% of the shares (26.1M), as of June 30, 2026. Among the top 20 institutions, 11 added shares and 9 reduced their stake in the latest filings. Short interest is 2.01% of the float, or 4.39 days of average trading volume. The share count rose 7.5% since 2014.
Related: VRTX analyst forecast, VRTX key metrics. See the VRTX stock overview for the latest quote and news.
VRTX ownership FAQ
Who owns the most Vertex stock?
The largest shareholders of Vertex are Capital World Investors (10.30%), BlackRock Inc (9.51%), Capital Research Global Investors (7.69%), Vanguard Capital Management, LLC (6.54%), State Street Corp (4.68%).
What percentage of Vertex is owned by institutions?
Institutions hold 98.2% of Vertex's shares outstanding; insiders hold 0.21%.
Which funds own Vertex?
The largest fund holders of Vertex are American Funds Growth Fd of Amer A (5.09%), Vanguard MStar Total Stk Mkt Idx Invest (3.18%), Vanguard 500 Index Investor (2.63%), American Funds American Balanced A (2.14%), Invesco QQQ Trust (2.09%).
What is Vertex's short interest?
4.5M shares of Vertex were sold short, 2.01% of the float; at the average daily volume it would take 4.39 days to cover.
Are insiders buying or selling Vertex?
Of the latest 20 reported insider transactions in Vertex (since December 3, 2025), 0 were purchases and 20 were sales.
How many shares of Vertex are outstanding?
Vertex has 253.5M shares outstanding, of which 252.7M are in the public float.