Arrowhead Pharmaceuticals, Inc. (ARWR) Key Metrics

NASDAQ: ARWRValuation, returns, debt and efficiency ratios over 10 years.

ARWR valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$7.90B
Enterprise value
$8.84B
P/E (TTM)
—
Forward P/E
111.1
PEG ratio
—
Price / sales
11.8
10-yr median 16.5
Price / book
20.6
10-yr median 10.2
EV / EBITDA
27.9
Dividend yield
—
Beta
1.30

ARWR key metrics, FY2016–FY2025

Fiscal year ended September 30, 2025 · U.S. dollars

ARWR valuation Price multiples at each fiscal year-end price.

Price / sales−99.1%
5.6
FY2025 · hover or tap a bar for each year
FY2017: 10.2FY2018: 99.3 (+874.9%)FY2019: 16.5 (−83.4%)FY2020: 49.3 (+199.4%)FY2021: 46.8 (−5.0%)FY2022: 14.3 (−69.4%)FY2023: 11.9 (−16.8%)FY2024: 653.4 (+5,383.8%)FY2025: 5.6 (−99.1%)
FY2016FY2025
Price / book−20.9%
9.9
FY2025 · hover or tap a bar for each year
FY2016: 4.7 (+56.6%)FY2017: 3.9 (−16.3%)FY2018: 16.7 (+325.9%)FY2019: 11.4 (−32.1%)FY2020: 9.4 (−17.3%)FY2021: 15.8 (+68.7%)FY2022: 8.7 (−44.8%)FY2023: 10.6 (+20.9%)FY2024: 12.5 (+18.4%)FY2025: 9.9 (−20.9%)
FY2016FY2025
EV / EBITDA
24.6
FY2025 · hover or tap a bar for each year
FY2019: 38.6FY2025: 24.6
FY2016FY2025
Price / free cash flow
29.4
FY2025 · hover or tap a bar for each year
FY2019: 17.3FY2021: 43.8FY2025: 29.4
FY2016FY2025
Free cash flow yield+29.4 pts
3.4%
FY2025 · hover or tap a bar for each year
FY2016: −15.2% (+5.3 pts)FY2017: −10.0% (+5.3 pts)FY2018: −3.0% (+6.9 pts)FY2019: 5.8% (+8.8 pts)FY2020: −2.5% (−8.3 pts)FY2021: 2.3% (+4.8 pts)FY2022: −5.4% (−7.7 pts)FY2023: −11.5% (−6.1 pts)FY2024: −26.0% (−14.5 pts)FY2025: 3.4% (+29.4 pts)
FY2016FY2025

ARWR valuation history

Fiscal year-endToday10-year median

ARWR returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

ARWR debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

ARWR cash returned to shareholders

DividendsBuybacksFree cash flow

ARWR price vs earnings per share

Share price at year-endEPS (right axis)

ARWR key metrics

FY2016–FY2025
Arrowhead Pharmaceuticals, Inc. key metrics by fiscal year
FY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Valuation
Market capitalization$4.61B$2.32B$2.87B$3.48B$6.48B$4.34B$2.78B$1.60B$320.0M$448.7M
Enterprise value$4.06B$2.49B$2.85B$3.19B$6.13B$4.04B$2.53B$1.53B$256.9M$366.1M
P/E ratio——————40.9———
Price / sales5.6653.411.914.346.849.316.599.310.2—
Price / book9.912.510.68.715.89.411.416.73.94.7
Price / free cash flow29.4———43.8—17.3———
Price / operating cash flow25.7———37.8—16.1———
EV / sales4.9701.511.813.144.445.915.094.78.2—
EV / EBITDA24.6—————38.6———
EV / free cash flow25.9———41.5—15.7———
Earnings yield−0.0%−25.8%−7.2%−5.1%−2.2%−1.9%2.4%−3.4%−10.7%−18.2%
Free cash flow yield3.4%−26.0%−11.5%−5.4%2.3%−2.5%5.8%−3.0%−10.0%−15.2%
Dividend yield———————0.0%0.0%0.0%
Shareholder yield (dividends + buybacks)———0.0%0.0%0.0%0.0%0.0%0.1%0.1%
Share price at fiscal year-end$34.49$19.37$26.87$33.05$62.43$43.06$28.18$19.17$4.33$7.35
Per share
Revenue per share$6.20$0.03$2.26$2.31$1.33$0.87$1.71$0.19$0.43$0.00
Earnings per share−$0.01−$5.00−$1.92−$1.67−$1.36−$0.84$0.69−$0.65−$0.47−$1.34
Operating cash flow per share$1.34−$3.86−$1.44−$1.29$1.65−$0.95$1.75−$0.56−$0.32−$1.06
Free cash flow per share$1.17−$5.05−$3.10−$1.79$1.42−$1.07$1.63−$0.58−$0.43−$1.12
Cash per share$6.87$5.68$3.78$3.57$3.55$3.13$2.62$0.92$0.89$1.40
Book value per share$3.48$1.55$2.54$3.78$3.94$4.58$2.48$1.15$1.10$1.57
Tangible book value per share$3.43$1.48$2.45$3.67$3.81$4.28$2.13$0.70$0.55$0.84
Dividends per share———————$0.00$0.00$0.00
Capex per share$0.17$1.18$1.66$0.50$0.23$0.12$0.12$0.02$0.11$0.06
Debt per share$2.74$7.11$3.59$0.77$0.25$0.21$0.12$0.03$0.03$0.04
Shares outstanding133.8M119.8M106.8M105.4M103.7M100.7M98.6M83.6M73.9M61.1M
Change in shares outstanding+11.7%+12.2%+1.3%+1.6%+3.0%+2.1%+17.9%+13.2%+21.0%+6.4%
Returns & profitability
Return on equity (ROE)−0.5%−262.5%−61.3%−43.7%−32.4%−23.9%39.9%−61.5%−38.8%−79.4%
Return on invested capital (ROIC)—−156.3%−91.3%−165.6%−100.6%−89.2%—−221.3%−186.8%−514.1%
Return on assets (ROA)−0.1%−62.9%−28.2%−25.2%−22.9%−19.4%29.5%−50.5%−29.6%−62.8%
Return on tangible assets−0.1%−53.0%−27.2%−26.0%−20.2%−17.2%21.5%−73.5%−54.5%−97.5%
Free cash flow margin18.9%—−137.3%−77.7%106.8%−122.5%95.4%−301.3%−101.4%—
Income quality (OCF / net income)——————2.55———
Financial health
Total debt$366.3M$851.9M$383.5M$81.6M$25.5M$21.1M$11.6M$2.3M$2.5M$2.7M
Cash & short-term investments$919.4M$681.0M$403.6M$376.4M$367.8M$315.5M$258.7M$76.5M$65.6M$85.4M
Net debt−$553.1M$171.0M−$20.1M−$294.8M−$342.2M−$294.4M−$247.1M−$74.2M−$63.1M−$82.6M
Debt / equity0.794.591.410.200.060.050.050.020.030.03
Debt / assets0.260.750.500.120.040.040.030.020.020.02
Net debt / EBITDA−3.36—————−3.76———
Current ratio4.866.743.982.922.627.922.736.373.633.53
Quick ratio4.866.743.983.072.597.822.706.273.583.48
Interest coverage1.1-18.6-11.2-35.5-24.4-0.00.0-0.1-0.1-0.3
Working capital$755.2M$592.3M$314.1M$266.4M$238.1M$281.7M$168.2M$66.4M$49.2M$64.9M
Invested capital−$87.0M$356.4M$251.2M$103.7M$66.6M$167.4M−$2.5M$21.6M$18.3M$12.9M
Tangible asset value$496.6M$182.5M$276.9M$406.4M$395.2M$431.1M$209.9M$57.7M$39.9M$50.7M
Net current asset value$68.8M−$253.3M−$58.9M$131.7M$83.3M$261.6M$159.4M$62.4M$44.7M$57.4M
Graham number——————$6.20———
Graham net-net per share$0.32−$2.24−$0.70$0.88$0.74$2.56$1.57$0.73$0.58$0.87
Capital allocation
Dividends paid———————$0$0$0
Share buybacks (net)———$0$0$0$0$54,667$438,838$634,187
Dividends + buybacks / free cash flow————0.0%—0.0%———
Capex / revenue2.7%3,983.9%73.4%21.7%17.0%13.6%7.1%8.8%25.2%2,438.0%
Capex / operating cash flow12.6%———13.8%—6.9%———
Capex / depreciation0.957.6114.155.062.852.012.700.301.691.18
Stock-based compensation / revenue7.6%2,083.0%32.5%49.7%55.4%49.3%7.3%52.4%25.1%7,323.7%
R&D / revenue73.2%13,776.9%142.2%122.2%149.2%140.4%45.4%299.2%147.3%26,181.8%
SG&A / revenue14.7%2,781.2%38.4%51.2%58.6%59.4%15.7%118.4%55.7%14,902.1%
Efficiency
Days sales outstanding1.50.01.18.814.63.11.14.50.8172.9
Days of inventory on hand———-302.1——1,978,471.35.86.22.9
Days payables outstanding221.7463.8565.8215.8——4,511,166.618.646.738.2
Cash conversion cycle (days)-220.2-463.8-564.8-509.2——-2,532,694.2-8.4-39.7137.5
Receivables turnover243.10—341.4741.7024.92116.78341.4481.70439.892.11
Payables turnover1.650.790.651.690.000.000.0019.587.819.55
Inventory turnover————0.000.000.0063.1259.07127.84
Asset turnover0.660.000.330.350.220.200.730.150.270.00
Average receivables$3.4M$0$705,000$5.8M$5.6M$753,517$494,368$197,586$71,398$75,000
Average payables$14.5M$23.6M$19.4M$6.2M$8.1M$7.2M$5.2M$3.4M$8.2M$8.6M
Average inventory———−$8.6M$4.3M$3.8M$2.3M$1.1M$1.1M$644,962
Intangibles / total assets0.5%0.8%1.3%1.7%1.9%5.9%9.8%33.6%39.3%34.6%

Computed from ARWR's annual financial statements (latest annual report filed November 25, 2025) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

ARWR valuation and financial ratios

Arrowhead Pharmaceuticals earned a return on equity of −0.5% in fiscal 2025. It ended the year with $366.3 million of debt and $919.4 million in cash and short-term investments, a net cash position of $553.1 million. The share count rose 119.1% from 61.1M to 133.8M over 9 years.

See the ARWR income statement, the ARWR chart for price history, or the ARWR stock overview for the latest quote and news.

ARWR key metrics FAQ

What is Arrowhead Pharmaceuticals's EV/EBITDA?

Arrowhead Pharmaceuticals's enterprise value was 24.6 times EBITDA at the end of fiscal 2025 (enterprise value $4.1 billion, EBITDA $164.8 million); the current EV/EBITDA is 27.9.

What is Arrowhead Pharmaceuticals's return on equity?

Arrowhead Pharmaceuticals's return on equity (ROE) was −0.5% in fiscal 2025: net income of -$1.6 million on average shareholders' equity of $325.7 million.

How much debt does Arrowhead Pharmaceuticals have?

Arrowhead Pharmaceuticals had total debt of $366.3 million at the end of fiscal 2025, a debt-to-equity ratio of 0.79 and more cash than debt.

What is Arrowhead Pharmaceuticals's free cash flow yield?

Arrowhead Pharmaceuticals generated $156.9 million of free cash flow in fiscal 2025, a free cash flow yield of 3.4% on its market value at year-end ($4.6 billion).

What is Arrowhead Pharmaceuticals's current ratio?

Arrowhead Pharmaceuticals's current ratio was 4.86 at the end of fiscal 2025: current assets were 4.86 times current liabilities.

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