OnKure Therapeutics, Inc. (OKUR) Ownership

NASDAQ: OKURTop holders, insider trades and short interest.

OKUR ownership summary

as of October 18, 2026
Institutions
93.4%
of shares outstanding
Insiders
10.17%
of shares outstanding
Shares outstanding
40.5M
Float
18.7M
shares available to trade
Short interest
3.36%
1.2M shares short
Days to cover
6.02
short interest down 11.0% vs prior month
  • Institutions 93.39%
  • Insiders 10.17%

OKUR top institutional holders

20 largest
OnKure Therapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1RA Capital Management, LLC9.87%4.0M$8.4M—June 30, 2026
2Bvf Inc7.99%3.2M$6.8M+1.3M (+63.5%)June 30, 2026
3StepStone Group LLC6.57%2.7M$5.6M—June 30, 2026
4ADAR1 Capital Management LLC5.53%2.2M$4.7M−196,257 (−8.1%)June 30, 2026
5Vivo Capital, LLC4.76%1.9M$4.0M—June 30, 2026
6Vestal Point Capital LP4.51%1.8M$3.8M−14,120 (−0.8%)June 30, 2026
7BlackRock Inc3.70%1.5M$3.1M+1.5M (+2,924.7%)June 30, 2026
8Trails Edge Capital Partners, LP3.55%1.4M$3.0M+1.4M (0.0%)June 30, 2026
9Vanguard Capital Management, LLC3.55%1.4M$3.0M+854,562 (+146.7%)June 30, 2026
10Adage Capital Partners Gp LLC2.98%1.2M$2.5M—June 30, 2026
11Citadel Advisors Llc2.93%1.2M$2.5M+1.1M (+3,058.1%)June 30, 2026
12Sio Capital Management, LLC2.66%1.1M$2.3M—June 30, 2026
13Prosight Management, LP2.42%979K$2.1M−1.2M (−54.6%)June 30, 2026
14Logos Global Management LP2.38%964K$2.0M+963,855 (0.0%)June 30, 2026
15Geode Capital Management, LLC1.79%724K$1.5M+625,688 (+633.6%)June 30, 2026
16NEA Management Company, LLC1.18%479K$1.0M—June 30, 2026
17State Street Corp1.14%464K$973,690+450,200 (+3,344.2%)June 30, 2026
18Ensign Peak Advisors Inc1.07%432K$906,425+431,631 (0.0%)June 30, 2026
19Renaissance Technologies Corp0.89%359K$753,350−18,512 (−4.9%)June 30, 2026
20Sofinnova Ventures0.79%322K$675,553+179,992 (+127.0%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 10 holders added 8.8M shares and 4 cut 1.4M.

OKUR top mutual fund and ETF holders

20 largest
OnKure Therapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.85%1.2M$2.4M—August 31, 2026
2iShares Russell 2000 ETF1.41%572K$1.2M−6,592 (−1.1%)September 30, 2026
3Fidelity Small Cap Index0.70%286K$599,571+1,966 (+0.7%)July 31, 2026
4iShares Russell 2000 Value ETF0.57%229K$480,621+348 (+0.2%)September 30, 2026
5Vanguard Russell 2000 ETF0.37%151K$316,867+3,000 (+2.0%)August 31, 2026
6Fidelity Extended Market Index0.33%135K$283,658−726 (−0.5%)August 31, 2026
7iShares Micro-Cap ETF0.21%84K$175,369−576 (−0.7%)September 30, 2026
8T. Rowe Price Health Care ETF0.19%79K$165,530+6,835 (+9.5%)September 30, 2026
9Fidelity Total Market Index0.19%78K$163,823—August 31, 2026
10Schwab Small Cap Index0.16%64K$133,644—August 31, 2026
11EA Bridgeway Ultra-Small Company Mkt ETF0.13%53K$111,871—September 30, 2026
12Fidelity Series Total Market Index0.13%52K$108,221−5,620 (−9.8%)August 31, 2026
13iShares Russell 2000 Small-Cap Idx Instl0.12%49K$102,892—August 31, 2026
14Fidelity Small Cap Value Index0.09%37K$76,782—July 31, 2026
15Fidelity VIP Disciplined Small Cap Init0.09%36K$74,871+35,653 (0.0%)July 31, 2026
16Nuveen Small Cap Blend Idx R60.09%35K$74,344—August 31, 2026
17Dimensional US Small Cap ETF0.08%32K$68,095—September 30, 2026
18Avantis US Small Cap Equity ETF0.08%31K$64,312—September 30, 2026
19Fidelity Nasdaq Composite Index0.07%27K$56,062—August 31, 2026
20EQ/2000 Managed Volatility IB0.07%26K$55,375—August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

OKUR insider transactions

latest 10
OnKure Therapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-03-23Jason A LeveroneSell$4.16301$1,252
2026-03-23Nicholas A SaccomanoSell$4.1686$358
2025-12-22Jason A LeveroneSell$2.97302$897
2025-12-22Nicholas A SaccomanoSell$2.9787$258
2025-09-22Jason A LeveroneSell$2.62303$794
2025-09-22Nicholas A SaccomanoSell$2.6288$231
2025-06-23Jason A LeveroneSell$2.38303$721
2025-06-23Nicholas A SaccomanoSell$2.3888$209
2025-05-15Cormorant Asset Management, LpSell$1.851,813,439$3.4M
2025-05-12Cormorant Asset Management, LpSell$1.9924,300$48,357

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

OKUR shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns OKUR

Institutional investors own 93.4% of OnKure Therapeutics's shares and insiders 10.17%. The largest holder is RA Capital Management, LLC with 9.87% of the shares (4.0M), as of June 30, 2026. Among the top 20 institutions, 10 added shares and 4 reduced their stake in the latest filings. Short interest is 3.36% of the float, or 6.02 days of average trading volume. The share count rose 575.8% since 2021.

Related: OKUR analyst forecast, OKUR key metrics. See the OKUR stock overview for the latest quote and news.

OKUR ownership FAQ

Who owns the most OnKure Therapeutics stock?

The largest shareholders of OnKure Therapeutics are RA Capital Management, LLC (9.87%), Bvf Inc (7.99%), StepStone Group LLC (6.57%), ADAR1 Capital Management LLC (5.53%), Vivo Capital, LLC (4.76%).

What percentage of OnKure Therapeutics is owned by institutions?

Institutions hold 93.4% of OnKure Therapeutics's shares outstanding; insiders hold 10.17%.

Which funds own OnKure Therapeutics?

The largest fund holders of OnKure Therapeutics are Vanguard MStar Total Stk Mkt Idx Invest (2.85%), iShares Russell 2000 ETF (1.41%), Fidelity Small Cap Index (0.70%), iShares Russell 2000 Value ETF (0.57%), Vanguard Russell 2000 ETF (0.37%).

What is OnKure Therapeutics's short interest?

1.2M shares of OnKure Therapeutics were sold short, 3.36% of the float; at the average daily volume it would take 6.02 days to cover.

Are insiders buying or selling OnKure Therapeutics?

Of the latest 10 reported insider transactions in OnKure Therapeutics (since May 12, 2025), 0 were purchases and 10 were sales.

How many shares of OnKure Therapeutics are outstanding?

OnKure Therapeutics has 40.5M shares outstanding, of which 18.7M are in the public float.

Biotechnology: ownership