OnKure Therapeutics, Inc. (OKUR) Key Metrics

NASDAQ: OKURValuation, returns, debt and efficiency ratios over 6 years.

OKUR valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$85.0M
Enterprise value
−$54.4M
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
—
Price / book
0.7
EV / EBITDA
0.0
Dividend yield
—
Beta
0.75

OKUR key metrics, 2020–2025

Fiscal year ended December 31, 2025 · U.S. dollars

OKUR valuation Price multiples at each fiscal year-end price.

Price / book−36.9%
0.7
2025 · hover or tap a bar for each year
2024: 1.12025: 0.7 (−36.9%)
20202025
Free cash flow yield−87.7 pts
−132.3%
2025 · hover or tap a bar for each year
2022: −9.0%2023: −16.3% (−7.3 pts)2024: −44.6% (−28.3 pts)2025: −132.3% (−87.7 pts)
20202025

OKUR valuation history

Fiscal year-endToday6-year median

OKUR returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

OKUR debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

OKUR price vs earnings per share

Share price at year-endEPS (right axis)

OKUR key metrics

2020–2025
OnKure Therapeutics, Inc. key metrics by fiscal year
202520242023202220212020
Valuation
Market capitalization$39.2M$114.7M$213.4M$310.8M——
Enterprise value−$19.3M$5.0M$184.2M$299.9M——
Price / book0.71.1————
Earnings yield−151.8%−45.9%−16.5%−9.5%——
Free cash flow yield−132.3%−44.6%−16.3%−9.0%——
Share price at fiscal year-end$2.90$8.60$16.00$23.30$85.50—
Per share
Revenue per share$0.00$0.00$0.00$0.00——
Earnings per share−$4.40−$3.95−$2.65−$2.21——
Operating cash flow per share−$3.83−$3.83−$2.59−$2.02——
Free cash flow per share−$3.84−$3.84−$2.61−$2.11——
Cash per share$4.37$8.30$2.24$0.87——
Book value per share$4.16$7.78−$7.63−$4.08——
Tangible book value per share$4.16$7.78−$7.63−$4.08——
Capex per share$0.00$0.00$0.02$0.09——
Debt per share$0.04$0.08$0.05$0.05——
Shares outstanding13.5M13.3M13.3M13.3M——
Change in shares outstanding+1.3%0.0%0.0%———
Returns & profitability
Return on equity (ROE)−74.4%———−75.7%—
Return on assets (ROA)−67.2%−69.9%−136.5%−34.7%−38.0%−35.2%
Return on tangible assets−95.8%−45.8%−98.8%−184.5%−25.8%−35.2%
Financial health
Total debt$549,000$1.1M$674,000$637,000—$92.7M
Cash & short-term investments$59.0M$110.8M$29.9M$11.5M$147.7M$53.6M
Net debt−$58.5M−$109.7M−$29.2M−$10.9M−$147.7M$39.1M
Debt / equity0.010.01————
Debt / assets0.010.010.020.04—1.68
Current ratio10.2810.734.642.4624.7912.01
Quick ratio10.2810.734.642.4624.7912.01
Interest coverage—-181.3————
Working capital$54.9M$102.5M$26.5M$8.1M$147.5M$50.4M
Invested capital−$2.3M−$5.8M−$131.0M−$65.3M−$459,000−$3.0M
Tangible asset value$56.2M$103.8M−$101.8M−$54.4M$147.2M−$42.1M
Net current asset value$54.9M$101.9M−$103.8M−$56.8M$146.9M−$42.3M
Graham net-net per share$3.93$7.47−$8.07−$4.41——
Capital allocation
Capex / depreciation0.060.080.442.933.960.65
Efficiency
Days payables outstanding967.71,760.21,934.81,738.8——
Payables turnover0.380.210.190.21——
Asset turnover0.000.000.000.000.000.00
Average payables$2.2M$3.2M$3.0M$2.5M——
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%0.0%

Computed from OKUR's annual financial statements (latest annual report filed March 12, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

OKUR valuation and financial ratios

OnKure Therapeutics earned a return on equity of −74.4% in fiscal 2025. It ended the year with $0.5 million of debt and $59.0 million in cash and short-term investments, a net cash position of $58.5 million.

See the OKUR income statement, the OKUR chart for price history, or the OKUR stock overview for the latest quote and news.

OKUR key metrics FAQ

What is OnKure Therapeutics's return on equity?

OnKure Therapeutics's return on equity (ROE) was −74.4% in fiscal 2025: net income of -$59.5 million on average shareholders' equity of $80.0 million.

How much debt does OnKure Therapeutics have?

OnKure Therapeutics had total debt of $0.5 million at the end of fiscal 2025, a debt-to-equity ratio of 0.01 and more cash than debt.

What is OnKure Therapeutics's free cash flow yield?

OnKure Therapeutics generated -$51.9 million of free cash flow in fiscal 2025, a free cash flow yield of −132.3% on its market value at year-end ($39.2 million).

What is OnKure Therapeutics's current ratio?

OnKure Therapeutics's current ratio was 10.28 at the end of fiscal 2025: current assets were 10.28 times current liabilities.

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