Madrigal Pharmaceuticals, Inc. (MDGL) Ownership

NASDAQ: MDGLTop holders, insider trades and short interest.

MDGL ownership summary

as of October 17, 2026
Institutions
104.3%
of shares outstanding
Insiders
5.83%
of shares outstanding
Shares outstanding
23.1M
Float
13.7M
shares available to trade
Short interest
12.19%
2.4M shares short
Days to cover
10.83
short interest up 6.3% vs prior month
  • Institutions 104.28%
  • Insiders 5.83%

MDGL top institutional holders

20 largest
Madrigal Pharmaceuticals, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1Baker Bros Advisors LP9.28%2.1M$963.9M+1,430 (+0.1%)June 30, 2026
2HHG PLC8.74%2.0M$907.9M+433,804 (+27.4%)March 31, 2026
3RTW INVESTMENTS, LLC8.63%2.0M$896.6M—June 30, 2026
4Jupiter Topco LLC8.38%1.9M$870.7M+1.9M (0.0%)June 30, 2026
5venBio Select Advisor LLC7.94%1.8M$824.5M+15,152 (+0.8%)June 30, 2026
6Paulson & Company Inc5.80%1.3M$602.7M−52,168 (−3.7%)June 30, 2026
7BlackRock Inc5.20%1.2M$540.0M−359,195 (−23.0%)June 30, 2026
8Vanguard Capital Management, LLC3.62%836K$375.8M+8,524 (+1.0%)June 30, 2026
9Wellington Management Company LLP3.57%826K$371.4M+130,756 (+18.8%)June 30, 2026
10Vanguard Portfolio Management, LLC3.38%782K$351.6M−59,414 (−7.1%)June 30, 2026
11State Street Corp2.28%527K$237.0M−82,468 (−13.5%)June 30, 2026
12Citadel Advisors Llc2.20%507K$228.1M+53,390 (+11.8%)June 30, 2026
13UBS Group AG1.74%402K$180.7M+283,929 (+241.1%)June 30, 2026
14Geode Capital Management, LLC1.62%375K$168.6M−80,990 (−17.8%)June 30, 2026
15FMR Inc1.54%356K$160.2M−155,527 (−30.4%)June 30, 2026
16William Blair Investment Management, LLC1.40%324K$145.8M−16,396 (−4.8%)June 30, 2026
17Amvescap Plc.1.30%301K$135.6M−28,084 (−8.5%)June 30, 2026
18Armistice Capital, LLC1.25%288K$129.5M+23,417 (+8.9%)June 30, 2026
19Lord, Abbett & Co LLC1.22%282K$126.6M+38,774 (+16.0%)June 30, 2026
20Assenagon Asset Management SA1.08%248K$111.7M+232,395 (+1,449.5%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 11 holders added 3.2M shares and 8 cut 834K.

MDGL top mutual fund and ETF holders

20 largest
Madrigal Pharmaceuticals, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.54%586K$263.6M−680 (−0.1%)August 31, 2026
2Vanguard Health Care Inv2.26%522K$234.7M+77,788 (+17.5%)June 30, 2026
3Vanguard Small Cap Index1.84%424K$190.9M+322 (+0.1%)August 31, 2026
4Polar Capital Biotech S Inc1.51%350K$157.2M+75,563 (+27.6%)August 31, 2026
5Janus Henderson Forty S1.47%339K$152.3M—August 31, 2026
6State Street® SPDR® S&P® Biotech ETF1.18%272K$122.4M−5,200 (−1.9%)September 30, 2026
7Vanguard MStar Small Cap Growth Indx Inv1.05%244K$109.5M−1,925 (−0.8%)August 31, 2026
8Janus Henderson Enterprise D1.01%233K$104.9M—August 31, 2026
9Vanguard Explorer Inv0.79%183K$82.1M+138,198 (+311.0%)June 30, 2026
10First Trust NYSE Arca Biotech ETF0.73%169K$75.9M—September 30, 2026
11iShares Biotechnology ETF0.73%168K$75.5M−1,272 (−0.8%)September 30, 2026
12Janus Henderson Global Life Sciences D0.67%154K$69.2M+8,467 (+5.8%)August 31, 2026
13Janus Henderson Glb Life Scn I2 USD0.64%148K$66.5M+10,280 (+7.5%)August 31, 2026
14Lord Abbett Growth Leaders I0.61%140K$63.2M—July 31, 2026
15Janus Global Life Science AUSD0.60%138K$61.9M+3,866 (+2.9%)June 30, 2026
16Invesco Discovery A0.57%131K$59.1M+6,502 (+5.2%)August 31, 2026
17Janus Henderson Contrarian D0.53%122K$55.0M−45,932 (−27.3%)August 31, 2026
18Pictet-Biotech P USD0.47%109K$49.2M−443 (−0.4%)June 30, 2026
19Janus Henderson Hrzn Biotec E2 USD0.46%106K$47.5M+11,421 (+12.1%)June 30, 2026
20Schwab US Small-Cap ETF™0.45%105K$47.0M+63 (+0.1%)September 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

MDGL insider transactions

latest 20
Madrigal Pharmaceuticals, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-03-06Mardi DierSell$430.871,982$853,984
2026-03-06Carole HuntsmanSell$431.94419$180,983
2026-03-06William John SiboldSell$431.941,663$718,316
2026-03-06Rebecca TaubSell$431.94491$212,083
2026-03-06Shannon T KelleySell$431.94360$155,498
2026-03-02Mardi DierSell$427.211,183$505,389
2026-01-26Carole HuntsmanSell$493.78910$449,340
2026-01-26Rebecca TaubSell$492.42647$318,596
2026-01-26William John SiboldSell$492.421,577$776,546
2026-01-20Rebecca TaubSell$490.772,238$1.1M
2026-01-20Shannon T KelleySell$497.36692$344,173
2026-01-09Paul A FriedmanSell$522.3924,520$12.8M
2026-01-09Rebecca TaubSell$522.4018,410$9.6M
2026-01-09Rebecca TaubSell$550.33240$132,079
2026-01-09Paul A FriedmanSell$551.24280$154,347
2025-12-10Paul A FriedmanSell$552.1824,800$13.7M
2025-12-10Rebecca TaubSell$552.1518,650$10.3M
2025-12-04William John SiboldSell$575.342,400$1.4M
2025-12-02Mardi DierSell$578.344,173$2.4M
2025-11-21Carole HuntsmanSell$553.111,958$1.1M

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

MDGL shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns MDGL

Institutional investors own 104.3% of Madrigal Pharmaceuticals's shares and insiders 5.83%. The largest holder is Baker Bros Advisors LP with 9.28% of the shares (2.1M), as of June 30, 2026. Among the top 20 institutions, 11 added shares and 8 reduced their stake in the latest filings. Short interest is 12.19% of the float, or 10.83 days of average trading volume. The share count rose 624.6% since 2014.

Related: MDGL analyst forecast, MDGL key metrics. See the MDGL stock overview for the latest quote and news.

MDGL ownership FAQ

Who owns the most Madrigal Pharmaceuticals stock?

The largest shareholders of Madrigal Pharmaceuticals are Baker Bros Advisors LP (9.28%), HHG PLC (8.74%), RTW INVESTMENTS, LLC (8.63%), Jupiter Topco LLC (8.38%), venBio Select Advisor LLC (7.94%).

What percentage of Madrigal Pharmaceuticals is owned by institutions?

Institutions hold 104.3% of Madrigal Pharmaceuticals's shares outstanding; insiders hold 5.83%.

Which funds own Madrigal Pharmaceuticals?

The largest fund holders of Madrigal Pharmaceuticals are Vanguard MStar Total Stk Mkt Idx Invest (2.54%), Vanguard Health Care Inv (2.26%), Vanguard Small Cap Index (1.84%), Polar Capital Biotech S Inc (1.51%), Janus Henderson Forty S (1.47%).

What is Madrigal Pharmaceuticals's short interest?

2.4M shares of Madrigal Pharmaceuticals were sold short, 12.19% of the float; at the average daily volume it would take 10.83 days to cover.

Are insiders buying or selling Madrigal Pharmaceuticals?

Of the latest 20 reported insider transactions in Madrigal Pharmaceuticals (since November 21, 2025), 0 were purchases and 20 were sales.

How many shares of Madrigal Pharmaceuticals are outstanding?

Madrigal Pharmaceuticals has 23.1M shares outstanding, of which 13.7M are in the public float.

Biotechnology: ownership