Zentalis Pharmaceuticals, Inc. (ZNTL) Ownership

NASDAQ: ZNTLTop holders, insider trades and short interest.

ZNTL ownership summary

as of October 18, 2026
Institutions
50.8%
of shares outstanding
Insiders
21.85%
of shares outstanding
Shares outstanding
98.1M
Float
56.6M
shares available to trade
Short interest
7.11%
6.0M shares short
Days to cover
5.11
short interest up 24.5% vs prior month
  • Institutions 50.79%
  • Insiders 21.85%
  • Other investors 27.36%

ZNTL top institutional holders

20 largest
Zentalis Pharmaceuticals, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
15AM Venture Management, LLC4.02%3.9M$8.4M—June 30, 2026
2BlackRock Inc3.83%3.8M$8.0M+2.5M (+195.6%)June 30, 2026
3Squadron Capital Management LLC3.77%3.7M$7.9M−331,000 (−8.2%)June 30, 2026
4Two Sigma Investments LLC3.08%3.0M$6.4M+68,410 (+2.3%)June 30, 2026
5Vanguard Capital Management, LLC2.89%2.8M$6.0M+524,962 (+22.7%)June 30, 2026
6Acadian Asset Management LLC2.73%2.7M$5.7M−166,352 (−5.8%)June 30, 2026
7Citadel Advisors Llc2.34%2.3M$4.9M+566,320 (+32.7%)June 30, 2026
8Renaissance Technologies Corp1.64%1.6M$3.4M−329,067 (−17.0%)June 30, 2026
9Opaleye Management Inc1.44%1.4M$3.0M—June 30, 2026
10Orbimed Advisors LLC1.42%1.4M$3.0M+1.4M (0.0%)June 30, 2026
11Decheng Capital LLC1.35%1.3M$2.8M—June 30, 2026
12Geode Capital Management, LLC1.31%1.3M$2.7M+663,081 (+106.8%)June 30, 2026
13Bank of America Corp1.14%1.1M$2.4M−17,644 (−1.6%)June 30, 2026
14Ishara Investments LP1.04%1.0M$2.2M−205,000 (−16.7%)June 30, 2026
15PRIMECAP Management Company0.98%957K$2.0M—June 30, 2026
16Pfizer Inc0.97%954K$2.0M—June 30, 2026
17Soleus Capital Management, L.P.0.97%950K$2.0M+950,000 (0.0%)June 30, 2026
18State Street Corp0.90%887K$1.9M+637,726 (+255.4%)June 30, 2026
19Vanguard Portfolio Management, LLC0.82%809K$1.7M+447,948 (+124.2%)June 30, 2026
20Connor Clark & Lunn Inv Mgmt Ltd0.77%758K$1.6M−33,968 (−4.3%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 9 holders added 7.7M shares and 6 cut 1.1M.

ZNTL top mutual fund and ETF holders

20 largest
Zentalis Pharmaceuticals, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.91%2.9M$6.1M+669,700 (+30.6%)August 31, 2026
2iShares Russell 2000 ETF1.34%1.3M$2.8M−15,104 (−1.1%)September 30, 2026
3PRIMECAP Odyssey Aggressive Growth0.69%676K$1.4M—June 30, 2026
4Fidelity Enhanced Small Cap Core ETF0.61%595K$1.3M+1,248 (+0.2%)September 30, 2026
5Fidelity Small Cap Index0.56%546K$1.2M+3,116 (+0.6%)July 31, 2026
6iShares Russell 2000 Value ETF0.50%488K$1.0M+740 (+0.2%)September 30, 2026
7Biotech Growth Ord0.48%470K$1.0M+244,568 (+108.3%)June 30, 2026
8Vanguard Strategic Small-Cap Equity Inv0.33%320K$682,580+111,130 (+53.1%)June 30, 2026
9Vanguard Russell 2000 ETF0.30%290K$616,703+1,007 (+0.3%)September 30, 2026
10Vanguard US Opportunities Ins USD Acc0.27%262K$557,890—June 30, 2026
11Fidelity Extended Market Index0.25%245K$521,464+1,166 (+0.5%)August 31, 2026
12Vanguard Health Care ETF0.23%224K$476,511+243 (+0.1%)September 30, 2026
13Federated Hermes MDT Small Cap Core ETF0.22%211K$450,476−1,764 (−0.8%)September 30, 2026
14Dimensional US Small Cap ETF0.18%181K$386,316—September 30, 2026
15iShares Micro-Cap ETF0.16%158K$335,961−1,088 (−0.7%)September 30, 2026
16Avantis US Small Cap Equity ETF0.15%144K$306,347+894 (+0.6%)September 30, 2026
17Sun Life Global Mid Cap Fund I0.14%136K$290,394—July 31, 2026
18Schwab Small Cap Index0.12%122K$259,198—August 31, 2026
19Invesco RAFI US 1500 Small-Mid ETF0.12%114K$242,481—September 30, 2026
20DFA US Micro Cap I0.11%104K$220,806+26,924 (+35.1%)August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

ZNTL insider transactions

latest 10
Zentalis Pharmaceuticals, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-02-10Vincent VultaggioSell$2.426,894$16,683
2026-02-09Ingmar BrunsSell$2.39335$801
2026-02-09Vincent VultaggioSell$2.393,379$8,076
2026-02-06Ingmar BrunsSell$2.432,962$7,198
2026-02-06Vincent VultaggioSell$2.4329,951$72,781
2026-02-03Vincent VultaggioSell$2.52556$1,401
2026-02-02Vincent VultaggioSell$2.552,540$6,477
2025-12-31Group WaltersBuy$1.206,459,973$7.8M
2025-12-15Matrix Capital Management CompSell$1.337,500,000$10.0M
2025-04-30Scott Dunseth MyersBuy$1.4021,000$29,400

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

ZNTL shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns ZNTL

Institutional investors own 50.8% of Zentalis Pharmaceuticals's shares and insiders 21.85%. The largest holder is 5AM Venture Management, LLC with 4.02% of the shares (3.9M), as of June 30, 2026. Among the top 20 institutions, 9 added shares and 6 reduced their stake in the latest filings. Short interest is 7.11% of the float, or 5.11 days of average trading volume. The share count rose 107.7% since 2019.

Related: ZNTL analyst forecast, ZNTL key metrics. See the ZNTL stock overview for the latest quote and news.

ZNTL ownership FAQ

Who owns the most Zentalis Pharmaceuticals stock?

The largest shareholders of Zentalis Pharmaceuticals are 5AM Venture Management, LLC (4.02%), BlackRock Inc (3.83%), Squadron Capital Management LLC (3.77%), Two Sigma Investments LLC (3.08%), Vanguard Capital Management, LLC (2.89%).

What percentage of Zentalis Pharmaceuticals is owned by institutions?

Institutions hold 50.8% of Zentalis Pharmaceuticals's shares outstanding; insiders hold 21.85%.

Which funds own Zentalis Pharmaceuticals?

The largest fund holders of Zentalis Pharmaceuticals are Vanguard MStar Total Stk Mkt Idx Invest (2.91%), iShares Russell 2000 ETF (1.34%), PRIMECAP Odyssey Aggressive Growth (0.69%), Fidelity Enhanced Small Cap Core ETF (0.61%), Fidelity Small Cap Index (0.56%).

What is Zentalis Pharmaceuticals's short interest?

6.0M shares of Zentalis Pharmaceuticals were sold short, 7.11% of the float; at the average daily volume it would take 5.11 days to cover.

Are insiders buying or selling Zentalis Pharmaceuticals?

Of the latest 10 reported insider transactions in Zentalis Pharmaceuticals (since April 30, 2025), 2 were purchases and 8 were sales.

How many shares of Zentalis Pharmaceuticals are outstanding?

Zentalis Pharmaceuticals has 98.1M shares outstanding, of which 56.6M are in the public float.

Biotechnology: ownership