Zentalis Pharmaceuticals, Inc. (ZNTL) Cash Flow Statement

NASDAQ: ZNTLOperating cash, capex, free cash flow and buybacks.

Where ZNTL’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$125.2M
Capital expenditures
$0
Free cash flow
−$125.2M
Returned to shareholders
$10.0M
Change in cash
$2.1M
cash at year-end $38.6M
Investments (net): $130.9MInvestments (net)$130.9MShares issued: $5.7MShares issued$5.7MAcquisitions & other: $698,000Acquisitions & other$698,000Cash used in operations: $125.2MCash used in operations$125.2M · 91%Share buybacks: $10.0MShare buybacks$10.0M · 7%Added to cash: $2.1MAdded to cash$2.1M · 2%$137.3M
Cash from operations
−$125.2M
Investments (net)
+$130.9M
Acquisitions & other
+$698,000
Share buybacks (net)
−$10.0M
Shares issued
+$5.7M
Change in cash
$2.1M

Drawn to scale: where the cash came from and how it was used. Hover for values.

ZNTL operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

ZNTL cash flow trends, 2018–2025

Zentalis Pharmaceuticals, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$24.3M2018−$125.2M2025—
Capital expenditures$227,0002018$02025−100.0%
Free cash flow−$24.5M2018−$125.2M2025—
Free cash flow margin−174,842.9%2018−253.7%2024+174,589.1 pts
Stock-based compensation$308,0002018$20.7M2025+82.4%/yr
Share buybacks (net)$02018$10.0M2025—
Capex / revenue1,621.4%20180.3%2024−1,621.1 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

ZNTL cash flow by activity

OperatingInvestingFinancingChange in cash

ZNTL net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

ZNTL cash flow statement

Zentalis Pharmaceuticals, Inc. annual cash flow statement
20252024202320222021202020192018
Operating activities
Net income−$137.1M−$165.9M−$292.2M−$237.1M−$166.1M−$118.5M−$46.4M−$23.4M
Depreciation & amortization$739,000$1.3M$1.4M$1.4M$544,000$160,000$111,000$51,000
Stock-based compensation$20.7M$67.3M$54.8M$46.8M$35.7M$23.1M$617,000$308,000
Change in working capital−$9.1M−$16.5M$5.9M$13.3M$16.6M$7.8M$6.5M−$1.2M
Other non-cash items−$526,000−$57.0M$22.3M$11.8M−$40.9M$573,000$0$0
Cash from operating activities−$125.2M−$170.9M−$207.8M−$163.8M−$154.1M−$86.8M−$39.1M−$24.3M
Investing activities
Capital expenditures$0−$221,000−$583,000−$2.5M−$6.1M−$758,000−$352,000−$227,000
Investments (net)$130.9M$176.6M−$14.3M−$111.6M$2.3M−$284.8M−$352,000−$227,000
Acquisitions & other investing$698,000$221,000−$29.6M$0−$14.3M$758,000$352,000$227,000
Cash from investing activities$131.6M$176.6M−$44.5M−$114.2M−$18.1M−$284.8M−$352,000−$227,000
Financing activities
Share repurchases & issuance (net)−$10.0M$0$0$261.0M−$1,146$346.2M$81.9M$9.5M
Shares issued$5.7M$349,000$287.0M$261.0M$179.7M$342.0M$81.9M$9.5M
Other financing$0−$241,000−$49.7M−$261.0M−$1.1M−$327.8M−$81.9M−$9.5M
Cash from financing activities−$4.3M$108,000$237.3M$261.0M$178.5M$360.4M$81.8M$9.5M
Summary
Net change in cash$2.1M$5.8M−$15.0M−$16.9M$6.3M−$11.2M$42.3M−$15.0M
Cash at end of period$38.6M$36.5M$30.7M$45.7M$62.6M$56.3M$67.5M$25.2M
Free cash flow−$125.2M−$171.1M−$208.4M−$166.3M−$160.2M−$87.6M−$39.5M−$24.5M
Free cash flow margin—−253.7%—————−174,842.9%
Capex / revenue—0.3%—————1,621.4%

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

ZNTL cash generation

In fiscal 2025 (ended December 31, 2025), Zentalis Pharmaceuticals generated -$125.2 million of cash from operations and spent $0 on capital expenditures, leaving free cash flow of -$125.2 million. It returned $10.0 million to shareholders through dividends ($0) and net share buybacks ($10.0 million). Cash and equivalents rose by $2.1 million over the year.

Related: ZNTL income statement, ZNTL balance sheet. See the ZNTL stock overview for the latest quote and news.

ZNTL cash flow FAQ

What is Zentalis Pharmaceuticals's free cash flow?

Zentalis Pharmaceuticals's free cash flow was -$125.2 million in fiscal 2025: -$125.2 million of operating cash flow minus $0 of capital expenditures It was -$171.1 million a year earlier..

How much cash does Zentalis Pharmaceuticals generate from operations?

Zentalis Pharmaceuticals generated -$125.2 million of cash from operating activities in fiscal 2025.

How much stock does Zentalis Pharmaceuticals buy back?

Zentalis Pharmaceuticals spent $10.0 million on net share repurchases in fiscal 2025.

Biotechnology: cash flow