Wave Life Sciences Ltd. (WVE) Ownership

NASDAQ: WVETop holders, insider trades and short interest.

WVE ownership summary

as of October 18, 2026
Institutions
85.7%
of shares outstanding
Insiders
15.58%
of shares outstanding
Shares outstanding
197.0M
Float
94.5M
shares available to trade
Short interest
11.62%
18.6M shares short
Days to cover
5.45
short interest up 5.2% vs prior month
  • Institutions 85.66%
  • Insiders 15.58%

WVE top institutional holders

20 largest
Wave Life Sciences Ltd. top institutional holders
#Holder% of sharesSharesValueChangeReported
1RA Capital Management, LLC13.69%27.0M$84.4M—June 30, 2026
2BlackRock Inc9.75%19.2M$60.1M+5.1M (+36.0%)June 30, 2026
3GSK PLC9.26%18.2M$57.1M—June 30, 2026
4Maverick Capital Ltd5.22%10.3M$32.2M+116,716 (+1.1%)June 30, 2026
5Driehaus Capital Management LLC2.76%5.4M$17.0M+12,122 (+0.2%)June 30, 2026
6PRIMECAP Management Company2.72%5.4M$16.8M+521,670 (+10.8%)June 30, 2026
7FMR Inc2.50%4.9M$15.4M−270,284 (−5.2%)June 30, 2026
8683 Capital Management LLC2.49%4.9M$15.3M+885,000 (+22.0%)March 31, 2026
9State Street Corp2.46%4.8M$15.1M+1.2M (+31.7%)June 30, 2026
10Readystate Asset Management LP2.40%4.7M$14.8M+4.7M (0.0%)June 30, 2026
11M28 Capital Management LP2.33%4.6M$14.4M—June 30, 2026
12Geode Capital Management, LLC1.96%3.9M$12.1M+290,899 (+8.1%)June 30, 2026
13Two Sigma Investments LLC1.88%3.7M$11.6M+1.8M (+97.4%)June 30, 2026
14Algert Global LLC1.43%2.8M$8.8M+1.5M (+114.2%)June 30, 2026
15Qube Research & Technologies1.41%2.8M$8.7M+2.6M (+1,680.4%)June 30, 2026
16Squarepoint Ops LLC1.29%2.5M$8.0M+1.1M (+73.8%)June 30, 2026
17Morgan Stanley - Brokerage Accounts1.23%2.4M$7.6M+1.1M (+78.0%)June 30, 2026
18Vanguard Portfolio Management, LLC1.07%2.1M$6.6M+934,544 (+79.5%)June 30, 2026
19Pfizer Inc0.95%1.9M$5.9M—June 30, 2026
20Millennium Management LLC0.92%1.8M$5.7M+839,041 (+86.3%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 15 holders added 22.7M shares and 1 cut 270K.

WVE top mutual fund and ETF holders

20 largest
Wave Life Sciences Ltd. top fund holders
#Holder% of sharesSharesValueChangeReported
1PRIMECAP Odyssey Aggressive Growth2.09%4.1M$12.9M+348,890 (+9.3%)June 30, 2026
2iShares Russell 2000 ETF1.84%3.6M$11.3M−41,664 (−1.1%)September 30, 2026
3State Street® SPDR® S&P® PhrmctlsETF0.98%1.9M$6.1M−24,068 (−1.2%)September 30, 2026
4Fidelity Growth Company Fund0.84%1.7M$5.2M—August 31, 2026
5abrdn Healthcare Investors0.82%1.6M$5.1M—September 30, 2026
6BlackRock Advantage Small Cap Core Instl0.77%1.5M$4.7M—August 31, 2026
7Fidelity Small Cap Index0.77%1.5M$4.7M+11,124 (+0.7%)July 31, 2026
8iShares Biotechnology ETF0.64%1.3M$3.9M−9,560 (−0.8%)September 30, 2026
9iShares Russell 2000 Value ETF0.62%1.2M$3.8M+1,842 (+0.2%)September 30, 2026
10abrdn Life Sciences Investors0.61%1.2M$3.8M+301,533 (+33.6%)September 30, 2026
11International Biotechnology Ord0.52%1.0M$3.2M+577,992 (+128.4%)June 30, 2026
12BNP Paribas US Small Cap ClassicC0.52%1.0M$3.2M−1,966 (−0.2%)August 31, 2026
13Vanguard Russell 2000 ETF0.42%820K$2.6M+27,302 (+3.4%)September 30, 2026
14Schwab US Small-Cap ETF™0.40%780K$2.4M+522 (+0.1%)September 30, 2026
15BNP Paribas Health Cr Innovtr Cl Cap0.36%716K$2.2M−130 (−0.0%)August 31, 2026
16MEDICAL BioHealth EUR Acc0.36%711K$2.2M+150 (+0.0%)August 31, 2026
17Federated Hermes MDT Small Cap Core IS0.32%640K$2.0M+289,482 (+82.7%)June 30, 2026
18North Square Dynamic Small Cap I0.32%621K$1.9M+35,470 (+6.1%)June 30, 2026
19Pictet-Biotech P USD0.31%608K$1.9M−2,466 (−0.4%)June 30, 2026
20Heptagon Driehaus US Micro Cap Eq C$ Acc0.30%587K$1.8M—August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

WVE insider transactions

latest 20
Wave Life Sciences Ltd. insider transactions
DateNameTransactionPriceSharesValue
2026-02-26Chris FrancisSell$15.0533,194$499,570
2026-02-09Chandra VargeeseSell$13.453,228$43,417
2026-02-09Chris FrancisSell$13.451,883$25,326
2026-02-09Kyle MoranSell$13.453,588$48,259
2026-02-09Paul BolnoSell$13.4510,480$140,956
2026-01-02Chris FrancisSell$16.039,375$150,281
2025-12-11Plc GskBuy$19.001,470,000$27.9M
2025-12-09Kyle MoranSell$20.0350,036$1.0M
2025-12-08Christian O HenrySell$14.6593,445$1.4M
2025-12-08Mark CorriganSell$13.4816,115$217,230
2025-12-08Kyle MoranSell$14.77210,000$3.1M
2025-12-08Heidi L WagnerSell$13.5014,000$189,000
2025-12-08Gregory L VerdineSell$13.4720,000$269,400
2025-12-08Chris FrancisSell$14.57441,031$6.4M
2025-12-08Adrian RawcliffeSell$15.0042,000$630,000
2025-11-13Adrian RawcliffeSell$6.7916,115$109,421
2025-08-22Gregory L VerdineSell$10.0010,000$100,000
2025-08-22Paul BolnoSell$10.10217,351$2.2M
2025-08-13Christian O HenrySell$8.819,670$85,193
2025-08-05Ken TakanashiSell$8.754,872$42,630

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

WVE shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns WVE

Institutional investors own 85.7% of Wave Life Sciences's shares and insiders 15.58%. The largest holder is RA Capital Management, LLC with 13.69% of the shares (27.0M), as of June 30, 2026. Among the top 20 institutions, 15 added shares and 1 reduced their stake in the latest filings. Short interest is 11.62% of the float, or 5.45 days of average trading volume. The share count rose 760.6% since 2014.

Related: WVE analyst forecast, WVE key metrics. See the WVE stock overview for the latest quote and news.

WVE ownership FAQ

Who owns the most Wave Life Sciences stock?

The largest shareholders of Wave Life Sciences are RA Capital Management, LLC (13.69%), BlackRock Inc (9.75%), GSK PLC (9.26%), Maverick Capital Ltd (5.22%), Driehaus Capital Management LLC (2.76%).

What percentage of Wave Life Sciences is owned by institutions?

Institutions hold 85.7% of Wave Life Sciences's shares outstanding; insiders hold 15.58%.

Which funds own Wave Life Sciences?

The largest fund holders of Wave Life Sciences are PRIMECAP Odyssey Aggressive Growth (2.09%), iShares Russell 2000 ETF (1.84%), State Street® SPDR® S&P® PhrmctlsETF (0.98%), Fidelity Growth Company Fund (0.84%), abrdn Healthcare Investors (0.82%).

What is Wave Life Sciences's short interest?

18.6M shares of Wave Life Sciences were sold short, 11.62% of the float; at the average daily volume it would take 5.45 days to cover.

Are insiders buying or selling Wave Life Sciences?

Of the latest 20 reported insider transactions in Wave Life Sciences (since August 5, 2025), 1 were purchases and 19 were sales.

How many shares of Wave Life Sciences are outstanding?

Wave Life Sciences has 197.0M shares outstanding, of which 94.5M are in the public float.

Biotechnology: ownership