Stoke Therapeutics, Inc. (STOK) Ownership

NASDAQ: STOKTop holders, insider trades and short interest.

STOK ownership summary

as of October 18, 2026
Institutions
125.4%
of shares outstanding
Insiders
3.68%
of shares outstanding
Shares outstanding
64.5M
Float
45.6M
shares available to trade
Short interest
18.52%
11.5M shares short
Days to cover
12.49
short interest up 3.2% vs prior month
  • Institutions 125.45%
  • Insiders 3.68%

STOK top institutional holders

20 largest
Stoke Therapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1BlackRock Inc9.11%5.9M$142.1M+491,643 (+9.1%)June 30, 2026
2RTW INVESTMENTS, LLC8.72%5.6M$135.9M—June 30, 2026
3FMR Inc8.23%5.3M$128.4M−70,566 (−1.3%)June 30, 2026
4Lynx1 Capital Management, LP6.26%4.0M$97.6M−725,269 (−15.2%)June 30, 2026
5Redmile Group, LLC6.12%3.9M$95.4M−218,200 (−5.2%)June 30, 2026
6Wellington Management Company LLP5.45%3.5M$85.1M+423,601 (+13.7%)June 30, 2026
7Morgan Stanley - Brokerage Accounts5.35%3.5M$83.5M+29,515 (+0.9%)June 30, 2026
8Baker Bros Advisors LP5.17%3.3M$80.6M—June 30, 2026
9The Toronto-Dominion Bank4.92%3.2M$76.7M—June 30, 2026
10State Street Corp4.42%2.9M$68.9M+575,728 (+25.3%)June 30, 2026
11T. Rowe Price Associates, Inc.4.12%2.7M$64.3M+727,568 (+37.6%)June 30, 2026
12Vanguard Capital Management, LLC4.01%2.6M$62.5M+231,334 (+9.8%)June 30, 2026
13Bvf Inc3.95%2.5M$61.6M—June 30, 2026
14T. Rowe Price Investment Management,Inc.3.74%2.4M$58.4M+2.2M (+862.5%)June 30, 2026
15Assenagon Asset Management SA3.50%2.3M$54.5M+1.3M (+148.8%)June 30, 2026
16Siren, L.L.C.3.09%2.0M$48.2M—June 30, 2026
17Deerfield Management Co2.83%1.8M$44.1M—June 30, 2026
18Jupiter Topco LLC2.81%1.8M$43.9M+1.8M (0.0%)June 30, 2026
19HHG PLC2.50%1.6M$39.0M+161,848 (+11.2%)March 31, 2026
20Geode Capital Management, LLC2.36%1.5M$36.8M+202,049 (+15.3%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 11 holders added 8.2M shares and 3 cut 1.0M.

STOK top mutual fund and ETF holders

20 largest
Stoke Therapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.93%1.9M$45.7M−3,561 (−0.2%)August 31, 2026
2Vanguard Health Care Inv2.84%1.8M$44.2M+177,438 (+10.7%)June 30, 2026
3Fidelity Select Biotechnology2.30%1.5M$35.8M+19,500 (+1.3%)August 31, 2026
4iShares Russell 2000 ETF2.21%1.4M$34.5M−16,448 (−1.1%)September 30, 2026
5RTW Biotech Opportunities Ord2.19%1.4M$34.1M+953,780 (+208.6%)December 31, 2025
6State Street® SPDR® S&P® Biotech ETF2.05%1.3M$31.9M−25,250 (−1.9%)September 30, 2026
7Polar Capital Biotech S Inc1.22%790K$19.1M—August 31, 2026
8T. Rowe Price New Horizons1.03%664K$16.1M−27,136 (−3.9%)August 31, 2026
9Fidelity Select Health Care0.97%628K$15.2M—August 31, 2026
10Fidelity Small Cap Index0.93%602K$14.6M+5,304 (+0.9%)July 31, 2026
11Fidelity Small Cap Growth0.81%521K$12.6M—July 31, 2026
12iShares Russell 2000 Growth ETF0.80%516K$12.5M−653 (−0.1%)September 30, 2026
13Candriam Eqs L Biotech C USD Cap0.78%502K$12.1M—March 31, 2026
14T. Rowe Price Integrated US Sm Gr Eq0.77%496K$12.0M—August 31, 2026
15BlackRock Health Sciences Opps Inv A0.73%473K$11.4M—August 31, 2026
16Fidelity Stock Selector Small Cap0.67%435K$10.5M—July 31, 2026
17T. Rowe Price Small-Cap Stock0.65%421K$10.2M−27,280 (−6.1%)August 31, 2026
18iShares Biotechnology ETF0.65%417K$10.1M−3,160 (−0.8%)September 30, 2026
19BGF World Healthscience A20.60%385K$9.3M—June 30, 2026
20Schwab US Small-Cap ETF™0.53%340K$8.2M+225 (+0.1%)September 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

STOK insider transactions

latest 20
Stoke Therapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-03-19Barry TichoSell$29.991,461$43,815
2026-03-18Thomas LeggettSell$31.342,382$74,652
2026-03-18Jonathan AllanSell$31.344,628$145,042
2026-03-18Jason HoittSell$31.341,931$60,518
2026-03-18Barry TichoSell$31.346,686$209,539
2026-03-17Barry TichoSell$33.016,164$203,474
2026-03-17Jason HoittSell$33.011,781$58,791
2026-03-17Jonathan AllanSell$33.014,267$140,854
2026-03-17Thomas LeggettSell$33.012,196$72,490
2026-03-13Arthur A LevinSell$36.80605$22,264
2026-03-10Adrian R KrainerSell$39.7433,243$1.3M
2026-03-10Arthur TzianabosSell$40.004,355$174,200
2025-12-08Edward M Md KayeSell$32.2713,430$433,386
2025-12-08Jonathan AllanSell$32.283,978$128,410
2025-12-05Barry TichoSell$31.343,662$114,767
2025-12-05Edward M Md KayeSell$31.328,548$267,723
2025-12-05Jonathan AllanSell$31.298,785$274,883
2025-12-04Barry TichoSell$30.871,696$52,356
2025-12-04Jonathan AllanSell$30.871,018$31,426
2025-12-04Edward M Md KayeSell$30.876,453$199,204

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

STOK shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns STOK

Institutional investors own 125.4% of Stoke Therapeutics's shares and insiders 3.68%. The largest holder is BlackRock Inc with 9.11% of the shares (5.9M), as of June 30, 2026. Among the top 20 institutions, 11 added shares and 3 reduced their stake in the latest filings. Short interest is 18.52% of the float, or 12.49 days of average trading volume. The share count rose 148.3% since 2018.

Related: STOK analyst forecast, STOK key metrics. See the STOK stock overview for the latest quote and news.

STOK ownership FAQ

Who owns the most Stoke Therapeutics stock?

The largest shareholders of Stoke Therapeutics are BlackRock Inc (9.11%), RTW INVESTMENTS, LLC (8.72%), FMR Inc (8.23%), Lynx1 Capital Management, LP (6.26%), Redmile Group, LLC (6.12%).

What percentage of Stoke Therapeutics is owned by institutions?

Institutions hold 125.4% of Stoke Therapeutics's shares outstanding; insiders hold 3.68%.

Which funds own Stoke Therapeutics?

The largest fund holders of Stoke Therapeutics are Vanguard MStar Total Stk Mkt Idx Invest (2.93%), Vanguard Health Care Inv (2.84%), Fidelity Select Biotechnology (2.30%), iShares Russell 2000 ETF (2.21%), RTW Biotech Opportunities Ord (2.19%).

What is Stoke Therapeutics's short interest?

11.5M shares of Stoke Therapeutics were sold short, 18.52% of the float; at the average daily volume it would take 12.49 days to cover.

Are insiders buying or selling Stoke Therapeutics?

Of the latest 20 reported insider transactions in Stoke Therapeutics (since December 4, 2025), 0 were purchases and 20 were sales.

How many shares of Stoke Therapeutics are outstanding?

Stoke Therapeutics has 64.5M shares outstanding, of which 45.6M are in the public float.

Biotechnology: ownership