Relay Therapeutics, Inc. (RLAY) Ownership

NASDAQ: RLAYTop holders, insider trades and short interest.

RLAY ownership summary

as of October 18, 2026
Institutions
110.9%
of shares outstanding
Insiders
1.58%
of shares outstanding
Shares outstanding
219.1M
Float
145.5M
shares available to trade
Short interest
24.84%
46.7M shares short
Days to cover
13.32
short interest up 5.1% vs prior month
  • Institutions 110.91%
  • Insiders 1.58%

RLAY top institutional holders

20 largest
Relay Therapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1SB INVESTMENT ADVISERS (UK) LTD12.73%27.9M$454.3M—June 30, 2026
2FMR Inc9.18%20.1M$327.4M+16.4M (+444.2%)June 30, 2026
3Casdin Capital, LLC7.32%16.0M$261.1M+1.6M (+11.2%)June 30, 2026
4BlackRock Inc6.98%15.3M$248.9M+2.3M (+17.8%)June 30, 2026
5Perceptive Advisors LLC6.44%14.1M$229.6M+4.4M (+44.7%)June 30, 2026
6COMMODORE CAPITAL LP5.48%12.0M$195.4M−5.0M (−29.4%)June 30, 2026
7State Street Corp4.62%10.1M$164.8M+3.9M (+62.4%)June 30, 2026
8Vanguard Capital Management, LLC4.09%9.0M$145.9M+1.6M (+21.3%)June 30, 2026
9T. Rowe Price Associates, Inc.3.52%7.7M$125.5M+5.8M (+300.5%)June 30, 2026
10Nextech Invest, Ltd.3.09%6.8M$110.3M+1.2M (+22.6%)June 30, 2026
11Bellevue Group AG2.82%6.2M$100.7M−1.6M (−20.6%)June 30, 2026
12Geode Capital Management, LLC2.16%4.7M$76.9M+1.2M (+34.6%)June 30, 2026
13TCG Crossover Management, LLC1.95%4.3M$69.6M—June 30, 2026
14AllianceBernstein L.P.1.87%4.1M$66.7M+4.0M (+2,719.7%)June 30, 2026
15Morgan Stanley - Brokerage Accounts1.76%3.9M$62.7M+2.4M (+168.9%)June 30, 2026
16Siren, L.L.C.1.67%3.6M$59.4M+3.6M (0.0%)June 30, 2026
17The Goldman Sachs Group Inc1.56%3.4M$55.5M+866,840 (+34.1%)June 30, 2026
18Westfield Capital Management Company, L.P.1.53%3.3M$54.4M+3.3M (0.0%)June 30, 2026
19Kynam Capital Management, LP1.51%3.3M$53.7M+1.9M (+131.7%)June 30, 2026
20Dimensional Fund Advisors, Inc.1.43%3.1M$50.9M+187,028 (+6.4%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 16 holders added 54.7M shares and 2 cut 6.6M.

RLAY top mutual fund and ETF holders

20 largest
Relay Therapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest3.11%6.8M$111.0M−9,256 (−0.1%)August 31, 2026
2State Street® SPDR® S&P® Biotech ETF2.23%4.9M$79.7M−93,150 (−1.9%)September 30, 2026
3iShares Russell 2000 ETF2.15%4.7M$76.8M−54,400 (−1.1%)September 30, 2026
4Fidelity Select Health Care0.95%2.1M$33.9M—August 31, 2026
5Strategic Advisers Fidelity US TtlStk0.89%1.9M$31.6M+16,300 (+0.8%)August 31, 2026
6Fidelity Small Cap Growth0.88%1.9M$31.2M+237,300 (+14.1%)July 31, 2026
7Fidelity Advisor Biotechnology I0.84%1.9M$30.1M—August 31, 2026
8Harbor Small Cap Growth Instl0.83%1.8M$29.5M+158,790 (+9.6%)September 30, 2026
9Fidelity Small Cap Index0.81%1.8M$28.8M+15,462 (+0.9%)July 31, 2026
10Polar Capital Biotech S Inc0.77%1.7M$27.6M—August 31, 2026
11Fidelity Stock Selector Small Cap0.77%1.7M$27.4M—July 31, 2026
12Fidelity Select Biotechnology0.75%1.6M$26.7M—August 31, 2026
13T. Rowe Price Small-Cap Stock0.71%1.5M$25.2M+37,909 (+2.5%)September 30, 2026
14T. Rowe Price Integrated US Sm Gr Eq0.62%1.4M$22.2M—September 30, 2026
15iShares Russell 2000 Growth ETF0.61%1.3M$21.8M−1,697 (−0.1%)September 30, 2026
16iShares Biotechnology ETF0.61%1.3M$21.8M−10,120 (−0.8%)September 30, 2026
17T. Rowe Price Health Sciences0.58%1.3M$20.8M—September 30, 2026
18T. Rowe Price New Horizons0.58%1.3M$20.8M−158,067 (−11.0%)September 30, 2026
19Pictet-Biotech P USD0.52%1.1M$18.4M−4,593 (−0.4%)June 30, 2026
20Vanguard Russell 2000 ETF0.48%1.1M$17.2M+129,414 (+13.9%)September 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

RLAY insider transactions

latest 20
Relay Therapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-04-09Thomas CatinazzoSell$15.001,800$27,000
2026-04-07Thomas CatinazzoSell$13.0117,717$230,498
2026-01-28Donald A BergstromSell$8.452,686$22,697
2026-01-28Peter RahmerSell$8.451,354$11,441
2026-01-28Thomas CatinazzoSell$8.451,695$14,323
2026-01-27Donald A BergstromSell$7.6218,895$143,980
2026-01-27Peter RahmerSell$7.6211,684$89,032
2026-01-27Thomas CatinazzoSell$7.6213,820$105,308
2026-01-06Sanjiv PatelSell$7.8243,168$337,574
2025-11-03Sanjiv PatelSell$7.0062,073$434,511
2025-10-29Peter RahmerSell$7.5021,394$160,455
2025-10-28Thomas CatinazzoSell$7.2921,664$157,931
2025-10-28Peter RahmerSell$7.2919,135$139,494
2025-10-28Donald A BergstromSell$7.2930,897$225,239
2025-07-29Brian AdamsSell$3.6818,276$67,256
2025-07-29Donald A BergstromSell$3.6826,701$98,260
2025-07-29Peter RahmerSell$3.6815,724$57,864
2025-07-29Thomas CatinazzoSell$3.6818,380$67,638
2025-07-28Brian AdamsSell$3.741,637$6,122
2025-07-28Donald A BergstromSell$3.744,069$15,218

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

RLAY shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns RLAY

Institutional investors own 110.9% of Relay Therapeutics's shares and insiders 1.58%. The largest holder is SB INVESTMENT ADVISERS (UK) LTD with 12.73% of the shares (27.9M), as of June 30, 2026. Among the top 20 institutions, 16 added shares and 2 reduced their stake in the latest filings. Short interest is 24.84% of the float, or 13.32 days of average trading volume. The share count rose 4,378.2% since 2019.

Related: RLAY analyst forecast, RLAY key metrics. See the RLAY stock overview for the latest quote and news.

RLAY ownership FAQ

Who owns the most Relay Therapeutics stock?

The largest shareholders of Relay Therapeutics are SB INVESTMENT ADVISERS (UK) LTD (12.73%), FMR Inc (9.18%), Casdin Capital, LLC (7.32%), BlackRock Inc (6.98%), Perceptive Advisors LLC (6.44%).

What percentage of Relay Therapeutics is owned by institutions?

Institutions hold 110.9% of Relay Therapeutics's shares outstanding; insiders hold 1.58%.

Which funds own Relay Therapeutics?

The largest fund holders of Relay Therapeutics are Vanguard MStar Total Stk Mkt Idx Invest (3.11%), State Street® SPDR® S&P® Biotech ETF (2.23%), iShares Russell 2000 ETF (2.15%), Fidelity Select Health Care (0.95%), Strategic Advisers Fidelity US TtlStk (0.89%).

What is Relay Therapeutics's short interest?

46.7M shares of Relay Therapeutics were sold short, 24.84% of the float; at the average daily volume it would take 13.32 days to cover.

Are insiders buying or selling Relay Therapeutics?

Of the latest 20 reported insider transactions in Relay Therapeutics (since July 28, 2025), 0 were purchases and 20 were sales.

How many shares of Relay Therapeutics are outstanding?

Relay Therapeutics has 219.1M shares outstanding, of which 145.5M are in the public float.

Biotechnology: ownership