Relay Therapeutics, Inc. (RLAY) Key Metrics

NASDAQ: RLAYValuation, returns, debt and efficiency ratios over 8 years.

RLAY valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$3.57B
Enterprise value
$3.07B
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
344.7
10-yr median 58.8
Price / book
4.4
10-yr median 2.2
EV / EBITDA
—
Dividend yield
—
Beta
1.73

RLAY key metrics, 2018–2025

Fiscal year ended December 31, 2025 · U.S. dollars

RLAY valuation Price multiples at each fiscal year-end price.

Price / sales+60.7%
94.5
2025 · hover or tap a bar for each year
2020: 45.32021: 964.6 (+2,027.0%)2023: 52.82024: 58.8 (+11.3%)2025: 94.5 (+60.7%)
20182025
Price / book+238.3%
2.6
2025 · hover or tap a bar for each year
2020: 4.92021: 3.3 (−33.7%)2022: 1.8 (−45.8%)2023: 1.8 (+1.7%)2024: 0.8 (−57.8%)2025: 2.6 (+238.3%)
20182025
Free cash flow yield+26.4 pts
−16.2%
2025 · hover or tap a bar for each year
2020: −2.8%2021: −2.7% (+0.1 pts)2022: −14.2% (−11.6 pts)2023: −22.6% (−8.3 pts)2024: −42.7% (−20.1 pts)2025: −16.2% (+26.4 pts)
20182025

RLAY valuation history

Fiscal year-endToday8-year median

RLAY returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

RLAY debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

RLAY cash returned to shareholders

DividendsBuybacksFree cash flow

RLAY price vs earnings per share

Share price at year-endEPS (right axis)

RLAY key metrics

2018–2025
Relay Therapeutics, Inc. key metrics by fiscal year
20252024202320222021202020192018
Valuation
Market capitalization$1.45B$588.6M$1.35B$1.68B$2.92B$3.75B——
Enterprise value$929.6M−$144.2M$652.9M$735.6M$1.99B$3.09B——
Price / sales94.558.852.8—964.645.3——
Price / book2.60.81.81.83.34.9——
EV / sales60.5-14.425.6532.7655.837.4——
Earnings yield−19.0%−57.4%−25.3%−17.3%−12.5%−1.4%——
Free cash flow yield−16.2%−42.7%−22.6%−14.2%−2.7%−2.8%——
Shareholder yield (dividends + buybacks)0.0%0.0%—0.0%0.0%0.0%——
Share price at fiscal year-end$8.46$4.12$11.01$14.94$30.71$41.56——
Per share
Revenue per share$0.09$0.07$0.21$0.01$0.03$0.92——
Earnings per share−$1.61−$2.36−$2.79−$2.59−$3.82−$0.58——
Operating cash flow per share−$1.37−$1.74−$2.45−$2.04−$0.78−$1.14——
Free cash flow per share−$1.37−$1.76−$2.48−$2.13−$0.82−$1.16——
Cash per share$3.23$5.47$6.12$8.90$10.07$7.52——
Book value per share$3.30$5.44$6.13$8.47$9.44$8.46——
Tangible book value per share$3.30$5.43$6.12$8.45$9.41$8.46——
Capex per share$0.00$0.01$0.03$0.08$0.04$0.02——
Debt per share$0.19$0.34$0.44$0.51$0.24$0.27——
Shares outstanding171.6M142.9M122.6M112.2M95.1M90.2M——
Change in shares outstanding+20.1%+16.6%+9.2%+18.0%+5.5%———
Returns & profitability
Return on equity (ROE)−41.1%−44.2%−40.2%−31.4%−43.8%−18.0%——
Return on invested capital (ROIC)−531.6%−586.4%−914.8%—————
Return on assets (ROA)−37.0%−39.4%−35.2%−27.6%−40.2%−8.8%−16.2%−11.4%
Return on tangible assets−44.5%−38.9%−40.6%−26.5%−36.2%−6.6%−16.9%−11.4%
Free cash flow margin—————−126.3%——
Financial health
Total debt$32.5M$48.5M$53.5M$57.7M$22.9M$24.4M$24.8M$178,000
Cash & short-term investments$554.5M$781.3M$750.1M$998.9M$958.1M$678.1M$355.8M$421.5M
Net debt−$522.1M−$732.8M−$696.6M−$941.2M−$935.2M−$653.6M−$331.0M−$421.3M
Debt / equity0.060.060.070.060.030.03——
Debt / assets0.050.060.060.050.020.030.060.00
Current ratio22.6115.9525.4416.0040.1456.4930.0861.78
Quick ratio22.6115.9525.4415.8168.2073.9630.0861.78
Interest coverage———-34.1-441.5———
Working capital$552.7M$758.5M$739.8M$955.8M$951.9M$756.5M$348.6M$417.2M
Invested capital$45.0M$45.0M$55.4M$9.0M−$37.4M$109.7M−$511.4M−$532.3M
Tangible asset value$567.1M$775.5M$749.7M$947.9M$895.5M$763.3M−$180.4M−$110.9M
Net current asset value$524.0M$715.7M$678.1M$870.0M$865.6M$733.6M−$213.0M−$115.4M
Graham net-net per share$2.92$4.81$5.37$7.66$5.36$6.48——
Capital allocation
Share buybacks (net)$0$0—$0$0$0$0$82,000
Capex / revenue2.7%20.2%16.2%656.2%114.6%2.3%——
Capex / depreciation0.120.370.782.190.880.542.810.78
Stock-based compensation / revenue406.5%940.7%336.8%4,065.0%1,599.7%38.7%——
R&D / revenue1,702.3%3,188.7%1,291.9%17,838.9%9,760.6%120.8%——
SG&A / revenue369.3%759.4%291.0%4,712.9%1,831.8%46.7%——
Efficiency
Days sales outstanding——37.31,342.55,277.6365.0——
Days of inventory on hand———-503.5-991.8-24,484.4——
Days payables outstanding1,118.613.511.114.215.8686.1750.3797.3
Cash conversion cycle (days)——26.2824.94,270.0-24,805.5——
Receivables turnover——9.790.270.071.00——
Payables turnover0.3327.0732.9925.7823.160.530.490.46
Asset turnover0.020.010.030.000.000.140.000.00
Average receivables——$2.6M$5.1M$43.8M$82.7M——
Average payables$10.9M$11.7M$9.9M$9.4M$7.3M$6.7M$5.8M$4.7M
Average inventory———−$335.2M−$460.3M−$238.1M——
Intangibles / total assets0.0%0.3%0.3%0.2%0.2%0.0%0.0%0.0%

Computed from RLAY's annual financial statements (latest annual report filed February 26, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

RLAY valuation and financial ratios

Relay Therapeutics earned a return on equity of −41.1% and a return on invested capital of −531.6% in fiscal 2025. It ended the year with $32.5 million of debt and $554.5 million in cash and short-term investments, a net cash position of $522.1 million.

See the RLAY income statement, the RLAY chart for price history, or the RLAY stock overview for the latest quote and news.

RLAY key metrics FAQ

What is Relay Therapeutics's return on equity?

Relay Therapeutics's return on equity (ROE) was −41.1% in fiscal 2025: net income of -$276.5 million on average shareholders' equity of $672.4 million.

What is Relay Therapeutics's ROIC?

Relay Therapeutics's return on invested capital was −531.6% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Relay Therapeutics have?

Relay Therapeutics had total debt of $32.5 million at the end of fiscal 2025, a debt-to-equity ratio of 0.06 and more cash than debt.

What is Relay Therapeutics's free cash flow yield?

Relay Therapeutics generated -$235.9 million of free cash flow in fiscal 2025, a free cash flow yield of −16.2% on its market value at year-end ($1.5 billion).

What is Relay Therapeutics's current ratio?

Relay Therapeutics's current ratio was 22.61 at the end of fiscal 2025: current assets were 22.61 times current liabilities.

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