PTC Therapeutics, Inc. (PTCT) Ownership

NASDAQ: PTCTTop holders, insider trades and short interest.

PTCT ownership summary

as of October 18, 2026
Institutions
122.8%
of shares outstanding
Insiders
7.31%
of shares outstanding
Shares outstanding
83.5M
Float
73.7M
shares available to trade
Short interest
14.89%
9.2M shares short
Days to cover
7.61
short interest down 5.9% vs prior month
  • Institutions 122.77%
  • Insiders 7.31%

PTCT top institutional holders

20 largest
PTC Therapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1BlackRock Inc16.73%14.0M$827.3M+1.0M (+7.8%)June 30, 2026
2RTW INVESTMENTS, LLC9.28%7.7M$458.9M—June 30, 2026
3Jupiter Topco LLC8.67%7.2M$428.7M+7.2M (0.0%)June 30, 2026
4HHG PLC8.62%7.2M$426.1M+2.3M (+48.3%)March 31, 2026
5Vanguard Portfolio Management, LLC5.90%4.9M$291.9M+123,517 (+2.6%)June 30, 2026
6State Street Corp5.51%4.6M$272.4M+252,433 (+5.8%)June 30, 2026
7Wellington Management Company LLP4.95%4.1M$244.6M+185,663 (+4.7%)June 30, 2026
8Vanguard Capital Management, LLC4.48%3.7M$221.5M+62,871 (+1.7%)June 30, 2026
9Geode Capital Management, LLC2.64%2.2M$130.8M−2,578 (−0.1%)June 30, 2026
10The Toronto-Dominion Bank2.60%2.2M$128.3M−860,117 (−28.4%)June 30, 2026
11Westfield Capital Management Company, L.P.2.34%2.0M$115.9M+2.0M (0.0%)June 30, 2026
12Hood River Capital Management LLC2.08%1.7M$103.0M+74,054 (+4.4%)June 30, 2026
13William Blair Investment Management, LLC2.06%1.7M$102.1M+1.7M (0.0%)June 30, 2026
14D. E. Shaw & Co LP1.86%1.5M$91.8M−91,462 (−5.6%)June 30, 2026
15TANG CAPITAL MANAGEMENT LLC1.80%1.5M$88.9M—June 30, 2026
16Bank of America Corp1.74%1.5M$86.0M−434,564 (−23.0%)June 30, 2026
17Driehaus Capital Management LLC1.73%1.4M$85.3M+424,335 (+41.8%)June 30, 2026
18FMR Inc1.68%1.4M$82.8M−130,101 (−8.5%)June 30, 2026
19Jefferies Financial Group Inc1.63%1.4M$80.4M+2,583 (+0.2%)June 30, 2026
20Fuller & Thaler Asset Management Inc1.39%1.2M$68.5M+1.2M (0.0%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 13 holders added 16.6M shares and 5 cut 1.5M.

PTCT top mutual fund and ETF holders

20 largest
PTC Therapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1iShares Core S&P Small-Cap ETF5.96%5.0M$294.5M+1,074 (+0.0%)September 30, 2026
2Vanguard MStar Total Stk Mkt Idx Invest3.17%2.6M$156.5M−3,195 (−0.1%)August 31, 2026
3State Street® SPDR® S&P® Biotech ETF2.64%2.2M$130.4M−41,900 (−1.9%)September 30, 2026
4iShares Russell 2000 ETF2.57%2.1M$126.9M−24,704 (−1.1%)September 30, 2026
5Vanguard Health Care Inv2.45%2.0M$121.3M+9,634 (+0.5%)June 30, 2026
6Vanguard Small Cap Index2.14%1.8M$105.8M−124,116 (−6.5%)September 30, 2026
7Vanguard MStar Small Cap Growth Indx Inv1.19%994K$58.9M−101,687 (−9.3%)September 30, 2026
8Janus Henderson Global Life Sciences D1.18%982K$58.2M−13,413 (−1.3%)August 31, 2026
9Janus Global Life Science AUSD1.13%944K$55.9M+7,924 (+0.8%)June 30, 2026
10Janus Henderson Glb Life Scn I2 USD1.13%943K$55.9M−708 (−0.1%)August 31, 2026
11Fidelity Small Cap Index1.08%905K$53.6M+7,575 (+0.8%)July 31, 2026
12Hood River Small-Cap Growth Instl1.00%832K$49.3M−57,126 (−6.4%)June 30, 2026
13Janus Henderson Hrzn Biotec E2 USD0.98%816K$48.3M+12,993 (+1.6%)June 30, 2026
14iShares S&P Small-Cap 600 Growth ETF0.93%773K$45.8M—September 30, 2026
15State Street SPDR Port S&P 600 Sm CpETF0.91%761K$45.1M—September 30, 2026
16iShares Russell 2000 Growth ETF0.79%662K$39.2M−838 (−0.1%)September 30, 2026
17iShares Biotechnology ETF0.75%622K$36.8M−4,712 (−0.8%)September 30, 2026
18Harbor Small Cap Growth Instl0.73%613K$36.3M+54,800 (+9.8%)September 30, 2026
19Pictet-Biotech P USD0.71%589K$34.9M−2,388 (−0.4%)June 30, 2026
20Janus Henderson Triton D0.65%541K$32.0M—August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

PTCT insider transactions

latest 20
PTC Therapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-04-21Matthew B KleinSell$70.912,850$202,094
2026-04-06Mark Elliott BouldingSell$69.452,265$157,304
2026-04-02Lee Scott GoldenSell$67.99829$56,364
2026-04-01Neil Gregory AlmsteadSell$69.0452,003$3.6M
2026-03-12Matthew B KleinSell$64.082,662$170,581
2026-03-10Stephanie OkeySell$70.0015,167$1.1M
2026-03-05Lee Scott GoldenSell$63.3810,000$633,800
2026-03-05Neil Gregory AlmsteadSell$63.383,989$252,823
2026-03-05Stephanie OkeySell$63.386,333$401,386
2026-02-19Mark Elliott BouldingSell$69.483,019$209,760
2026-02-18Christine Marie UtterSell$69.362,494$172,984
2026-02-18Pierre GravierSell$69.362,992$207,525
2026-02-18Neil Gregory AlmsteadSell$69.3665$4,508
2026-02-18Neil Gregory AlmsteadSell$69.363,056$211,964
2026-02-18Matthew B KleinSell$69.367,371$511,253
2026-02-18Mark Elliott BouldingSell$69.363,081$213,698
2026-02-18Lee Scott GoldenSell$69.362,484$172,290
2026-02-18Eric PauwelsSell$69.363,019$209,398
2026-02-17Mark Elliott BouldingSell$69.292,813$194,913
2026-01-12Eric PauwelsSell$78.701,024$80,589

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

PTCT shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns PTCT

Institutional investors own 122.8% of PTC Therapeutics's shares and insiders 7.31%. The largest holder is BlackRock Inc with 16.73% of the shares (14.0M), as of June 30, 2026. Among the top 20 institutions, 13 added shares and 5 reduced their stake in the latest filings. Short interest is 14.89% of the float, or 7.61 days of average trading volume. The share count rose 150.0% since 2014.

Related: PTCT analyst forecast, PTCT key metrics. See the PTCT stock overview for the latest quote and news.

PTCT ownership FAQ

Who owns the most PTC Therapeutics stock?

The largest shareholders of PTC Therapeutics are BlackRock Inc (16.73%), RTW INVESTMENTS, LLC (9.28%), Jupiter Topco LLC (8.67%), HHG PLC (8.62%), Vanguard Portfolio Management, LLC (5.90%).

What percentage of PTC Therapeutics is owned by institutions?

Institutions hold 122.8% of PTC Therapeutics's shares outstanding; insiders hold 7.31%.

Which funds own PTC Therapeutics?

The largest fund holders of PTC Therapeutics are iShares Core S&P Small-Cap ETF (5.96%), Vanguard MStar Total Stk Mkt Idx Invest (3.17%), State Street® SPDR® S&P® Biotech ETF (2.64%), iShares Russell 2000 ETF (2.57%), Vanguard Health Care Inv (2.45%).

What is PTC Therapeutics's short interest?

9.2M shares of PTC Therapeutics were sold short, 14.89% of the float; at the average daily volume it would take 7.61 days to cover.

Are insiders buying or selling PTC Therapeutics?

Of the latest 20 reported insider transactions in PTC Therapeutics (since January 12, 2026), 0 were purchases and 20 were sales.

How many shares of PTC Therapeutics are outstanding?

PTC Therapeutics has 83.5M shares outstanding, of which 73.7M are in the public float.

Biotechnology: ownership