PTC Therapeutics, Inc. (PTCT) Cash Flow Statement

NASDAQ: PTCTOperating cash, capex, free cash flow and buybacks.

Where PTCT’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
$711.2M
Capital expenditures
$300.0M
17.3% of revenue
Free cash flow
$411.2M
23.8% margin
Returned to shareholders
—
Change in cash
$203.0M
cash at year-end $998.3M
Cash from operations: $711.2MCash from operations$711.2MOther financing: $332.7MOther financing$332.7MCurrency & other: $21.2MCurrency & other$21.2MInvestments (net): $562.0MInvestments (net)$562.0M · 53%Capital expenditures: $300.0MCapital expenditures$300.0M · 28%Added to cash: $203.0MAdded to cash$203.0M · 19%$1.07B
Cash from operations
$711.2M
Capital expenditures
−$300.0M
Investments (net)
−$562.0M
Other financing
+$332.7M
Currency & other
+$21.2M
Change in cash
$203.0M

Drawn to scale: where the cash came from and how it was used. Hover for values.

PTCT operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

PTCT cash flow trends, 2016–2025

PTC Therapeutics, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$103.6M2016$711.2M2025—
Capital expenditures$1.8M2016$300.0M2025+76.8%/yr
Free cash flow−$105.3M2016$411.2M2025—
Free cash flow margin−127.4%201623.8%2025+151.1 pts
Stock-based compensation$35.0M2016$74.5M2025+8.8%/yr
Dividends paid$02016$02017—
Share buybacks (net)$02016$02022—
Capex / revenue2.1%201617.3%2025+15.2 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

PTCT cash flow by activity

OperatingInvestingFinancingChange in cash

PTCT net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

PTCT cash flow statement

PTC Therapeutics, Inc. annual cash flow statement
2025202420232022202120202019201820172016
Operating activities
Net income$682.6M−$363.3M−$626.6M−$559.0M−$523.9M−$438.2M−$251.6M−$128.1M−$79.0M−$142.1M
Depreciation & amortization$38.8M$75.7M$236.6M$128.8M$64.1M$43.5M$32.2M$26.1M$17.7M$3.3M
Stock-based compensation$74.5M$74.6M$131.2M$110.3M$103.5M$70.3M$42.1M$33.3M$30.6M$35.0M
Change in working capital−$47.9M$102.5M−$4.0M−$85.3M−$23.8M$36.9M$20.4M$14.2M$13.2M−$9.0M
Other non-cash items−$36.9M$2.8M$104.4M$48.5M$128.7M$93.4M$58.2M$26.9M$7.5M$9.2M
Cash from operating activities$711.2M−$107.7M−$158.4M−$356.7M−$251.3M−$194.1M−$98.6M−$27.6M−$10.1M−$103.6M
Investing activities
Capital expenditures−$300.0M−$74.2M−$120.6M−$152.5M−$85.3M−$56.0M−$45.4M−$15.5M−$3.1M−$1.8M
Investments (net)−$562.0M$44.2M−$49.9M$442.6M$304.5M−$505.6M−$341.8M$21.8M$93.4M$106.3M
Acquisitions & other investing$70,000$74.2M−$6.2M$0$0$0$0−$48.9M−$77.2M$0
Cash from investing activities−$862.0M$44.2M−$176.7M$290.2M$219.2M−$561.5M−$387.2M−$42.6M$13.1M$104.5M
Financing activities
Dividends paid————————$0$0
Share repurchases & issuance (net)———$71.1M$23.1M$103.6M$345.6M$131.6M$2.2M$968,000
Net borrowing (repayment)−$1.6M−$1.5M−$301.4M$138.5M−$2.2M−$28.9M$267.6M$267.6M−$432,000$40.0M
Shares issued$0$0$0$50.0M$0$28.1M$323.8M$117.9M$0$0
Other financing$332.7M$257.4M$947.8M−$91.7M$0$566.0M−$323.8M−$385.5M$42.5M−$40.0M
Cash from financing activities$331.1M$255.9M$646.4M$168.0M$20.9M$668.7M$613.2M$131.6M$44.2M$968,000
Summary
Net change in cash$203.0M$185.0M$314.4M$98.7M−$19.1M−$79.2M$126.0M$57.7M$53.5M$299,000
Cash at end of period$998.3M$795.3M$610.3M$295.9M$197.2M$216.3M$295.5M$169.5M$111.8M$58.3M
Free cash flow$411.2M−$181.9M−$279.0M−$509.1M−$336.7M−$250.0M−$144.1M−$43.2M−$13.2M−$105.3M
Free cash flow margin23.8%−22.6%−29.8%−72.9%−62.5%−65.7%−46.9%−16.3%−6.8%−127.4%
Capex / revenue17.3%9.2%12.9%21.8%15.8%14.7%14.8%5.9%1.6%2.1%
Operating cash flow / net income1.04—————————

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

PTCT cash generation

In fiscal 2025 (ended December 31, 2025), PTC Therapeutics generated $711.2 million of cash from operations and spent $300.0 million on capital expenditures, leaving free cash flow of $411.2 million, 23.8% of revenue. Cash and equivalents rose by $203.0 million over the year.

Related: PTCT income statement, PTCT balance sheet. See the PTCT stock overview for the latest quote and news.

PTCT cash flow FAQ

What is PTC Therapeutics's free cash flow?

PTC Therapeutics's free cash flow was $411.2 million in fiscal 2025: $711.2 million of operating cash flow minus $300.0 million of capital expenditures It was -$181.9 million a year earlier..

How much cash does PTC Therapeutics generate from operations?

PTC Therapeutics generated $711.2 million of cash from operating activities in fiscal 2025, 1.04 times its net income of $682.6 million.

How much does PTC Therapeutics spend on capital expenditures?

PTC Therapeutics spent $300.0 million on capital expenditures in fiscal 2025, 17.3% of revenue, compared with $74.2 million the year before.

Biotechnology: cash flow