Prothena Corporation plc (PRTA) Ownership

NASDAQ: PRTATop holders, insider trades and short interest.

PRTA ownership summary

as of October 18, 2026
Institutions
93.2%
of shares outstanding
Insiders
22.56%
of shares outstanding
Shares outstanding
51.3M
Float
34.1M
shares available to trade
Short interest
18.79%
8.0M shares short
Days to cover
17.58
short interest down 6.2% vs prior month
  • Institutions 93.21%
  • Insiders 22.56%

PRTA top institutional holders

20 largest
Prothena Corporation plc top institutional holders
#Holder% of sharesSharesValueChangeReported
1FMR Inc14.02%7.2M$60.1M−352,000 (−4.7%)June 30, 2026
2Rubric Capital Management LP9.74%5.0M$41.8M—June 30, 2026
3BlackRock Inc9.48%4.9M$40.6M+223,795 (+4.8%)June 30, 2026
4State Street Corp4.66%2.4M$20.0M+454,926 (+23.5%)June 30, 2026
5Acadian Asset Management LLC3.92%2.0M$16.8M+463,052 (+29.9%)June 30, 2026
6Vanguard Portfolio Management, LLC3.22%1.7M$13.8M+205,314 (+14.2%)June 30, 2026
7D. E. Shaw & Co LP3.14%1.6M$13.5M−151,890 (−8.6%)June 30, 2026
8ADAR1 Capital Management LLC3.03%1.6M$13.0M−26,908 (−1.7%)June 30, 2026
9Two Sigma Investments LLC2.46%1.3M$10.6M+59,009 (+4.9%)June 30, 2026
10Palo Alto Investors, LLC2.23%1.1M$9.5M−65,413 (−5.4%)June 30, 2026
11Geode Capital Management, LLC2.19%1.1M$9.4M+27,711 (+2.5%)June 30, 2026
12Federated Hermes Inc2.11%1.1M$9.1M+24,552 (+2.3%)June 30, 2026
13Morgan Stanley - Brokerage Accounts1.94%995K$8.3M−235,100 (−19.1%)June 30, 2026
14The Goldman Sachs Group Inc1.91%980K$8.2M+160,845 (+19.6%)June 30, 2026
15Jacobs Levy Equity Management, Inc.1.88%966K$8.1M−6,029 (−0.6%)June 30, 2026
16Dimensional Fund Advisors, Inc.1.76%906K$7.6M+123,048 (+15.7%)June 30, 2026
17Qube Research & Technologies1.54%791K$6.6M+176,566 (+28.7%)June 30, 2026
18Renaissance Technologies Corp1.36%698K$5.8M+90,100 (+14.8%)June 30, 2026
19Man Group PLC1.32%678K$5.7M+296,542 (+77.7%)June 30, 2026
20Mariner Wealth Advisors LLC1.22%625K$5.2M+62,013 (+11.0%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 13 holders added 2.4M shares and 6 cut 837K.

PRTA top mutual fund and ETF holders

20 largest
Prothena Corporation plc top fund holders
#Holder% of sharesSharesValueChangeReported
1Fidelity Growth Company Fund4.26%2.2M$18.2M−43,300 (−1.9%)August 31, 2026
2iShares Russell 2000 ETF2.18%1.1M$9.4M−12,928 (−1.1%)September 30, 2026
3State Street® SPDR® S&P® Biotech ETF1.77%910K$7.6M−17,400 (−1.9%)September 30, 2026
4Vanguard Explorer Inv1.48%757K$6.3M+139,978 (+22.7%)June 30, 2026
5Fidelity Series Growth Company1.41%724K$6.0M−14,300 (−1.9%)August 31, 2026
6Fidelity Small Cap Index0.95%486K$4.1M+4,598 (+1.0%)July 31, 2026
7Fidelity Select Biotechnology0.92%473K$3.9M−9,300 (−1.9%)August 31, 2026
8Fidelity Growth Company K60.79%407K$3.4M−8,100 (−2.0%)August 31, 2026
9Federated Hermes MDT Small Cap Core IS0.77%394K$3.3M—June 30, 2026
10iShares Biotechnology ETF0.68%350K$2.9M−2,648 (−0.8%)September 30, 2026
11Vanguard Strategic Small-Cap Equity Inv0.65%333K$2.8M—June 30, 2026
12BlackRock Advantage Small Cap Core Instl0.58%300K$2.5M+5,779 (+2.0%)August 31, 2026
13Vanguard Russell 2000 ETF0.49%252K$2.1M−3,600 (−1.4%)September 30, 2026
14DFA US Small Cap I0.47%242K$2.0M—August 31, 2026
15iShares Russell 2000 Growth ETF0.46%237K$2.0M−300 (−0.1%)September 30, 2026
16Bridge Builder Small/Mid Cap Value0.43%218K$1.8M+199,549 (+1,057.5%)September 30, 2026
17Schwab US Small-Cap ETF™0.42%214K$1.8M+144 (+0.1%)September 30, 2026
18Federated Hermes MDT Small Cap Core ETF0.40%204K$1.7M−1,701 (−0.8%)September 30, 2026
19Fidelity Extended Market Index0.39%200K$1.7M+52,907 (+35.8%)August 31, 2026
20Canada Life US Small-Mid Cap Growth F0.34%175K$1.5M—July 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

PRTA insider transactions

latest 20
Prothena Corporation plc insider transactions
DateNameTransactionPriceSharesValue
2025-01-14William P ScullyBuy$12.79100,000$1.3M
2024-12-31William P ScullyBuy$13.0132,000$416,320
2024-12-20William P ScullyBuy$15.912,000$31,820
2024-12-18William P ScullyBuy$13.9373,436$1.0M
2024-01-24Karin L. WalkerSell$34.005,000$170,000
2023-12-20Karin L. WalkerSell$37.195,000$185,950
2023-11-30Karin L. WalkerSell$34.005,000$170,000
2023-10-25Karin L. WalkerSell$41.045,000$205,200
2023-10-11Brandon S. SmithSell$46.754,000$187,000
2023-10-04Carol D. KarpSell$46.625,000$233,100
2023-09-27Michael J. MalecekSell$47.385,000$236,900
2023-09-19Karin L. WalkerSell$52.365,000$261,800
2023-09-13Brandon S. SmithSell$55.494,000$221,960
2023-09-13Hideki GarrenSell$55.482,000$110,960
2023-09-06Carol D. KarpSell$54.765,000$273,800
2023-08-30Michael J. MalecekSell$55.015,000$275,050
2023-08-18Karin L. WalkerSell$57.185,000$285,900
2023-08-16Hideki GarrenSell$58.742,000$117,480
2023-08-16Brandon S. SmithSell$58.714,000$234,840
2023-08-02Wagner M. ZagoSell$67.054,000$268,200

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

PRTA shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns PRTA

Institutional investors own 93.2% of Prothena's shares and insiders 22.56%. The largest holder is FMR Inc with 14.02% of the shares (7.2M), as of June 30, 2026. Among the top 20 institutions, 13 added shares and 6 reduced their stake in the latest filings. Short interest is 18.79% of the float, or 17.58 days of average trading volume. The share count rose 96.6% since 2014.

Related: PRTA analyst forecast, PRTA key metrics. See the PRTA stock overview for the latest quote and news.

PRTA ownership FAQ

Who owns the most Prothena stock?

The largest shareholders of Prothena are FMR Inc (14.02%), Rubric Capital Management LP (9.74%), BlackRock Inc (9.48%), State Street Corp (4.66%), Acadian Asset Management LLC (3.92%).

What percentage of Prothena is owned by institutions?

Institutions hold 93.2% of Prothena's shares outstanding; insiders hold 22.56%.

Which funds own Prothena?

The largest fund holders of Prothena are Fidelity Growth Company Fund (4.26%), iShares Russell 2000 ETF (2.18%), State Street® SPDR® S&P® Biotech ETF (1.77%), Vanguard Explorer Inv (1.48%), Fidelity Series Growth Company (1.41%).

What is Prothena's short interest?

8.0M shares of Prothena were sold short, 18.79% of the float; at the average daily volume it would take 17.58 days to cover.

Are insiders buying or selling Prothena?

Of the latest 20 reported insider transactions in Prothena (since August 2, 2023), 4 were purchases and 16 were sales.

How many shares of Prothena are outstanding?

Prothena has 51.3M shares outstanding, of which 34.1M are in the public float.

Biotechnology: ownership