Prothena Corporation plc (PRTA) Cash Flow Statement

NASDAQ: PRTAOperating cash, capex, free cash flow and buybacks.

Where PRTA’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$163.6M
Capital expenditures
$138,000
1.4% of revenue
Free cash flow
−$163.7M
−1,690.6% margin
Returned to shareholders
$139,000
Change in cash
−$163.9M
cash at year-end $308.4M
Drawn from cash: $163.9MDrawn from cash$163.9MCash used in operations: $163.6MCash used in operations$163.6M · 100%Capital expenditures: $138,000Capital expenditures$138,000 · 0%$163.9M
Cash from operations
−$163.6M
Change in cash
−$163.9M

Drawn to scale: where the cash came from and how it was used. Hover for values.

PRTA operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

PRTA cash flow trends, 2016–2025

Prothena Corporation plc cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$117.3M2016−$163.6M2025—
Capital expenditures$16.6M2016$138,0002025−41.3%/yr
Free cash flow−$133.9M2016−$163.7M2025—
Free cash flow margin−12,693.2%2016−1,690.6%2025+11,002.6 pts
Stock-based compensation$24.9M2016$37.6M2025+4.7%/yr
Dividends paid$02016$02017—
Share buybacks (net)$02016$139,0002025—
Capex / revenue1,577.6%20161.4%2025−1,576.2 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

PRTA cash flow by activity

OperatingInvestingFinancingChange in cash

PRTA net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

PRTA cash flow statement

Prothena Corporation plc annual cash flow statement
2025202420232022202120202019201820172016
Operating activities
Net income−$244.1M−$122.3M−$147.0M−$116.9M$67.0M−$111.1M−$77.7M−$155.6M−$153.2M−$160.1M
Depreciation & amortization$895,000$893,000$928,000$744,000$1.1M$1.5M$6.8M$3.2M$3.1M$2.4M
Stock-based compensation$37.6M$46.0M$40.9M$31.3M$24.7M$22.0M$23.6M$27.0M$26.8M$24.9M
Change in working capital−$4.2M−$67.9M−$20.5M−$18.8M−$10.4M$3.5M−$4.4M$94.5M−$7.2M$18.9M
Other non-cash items$46.1M−$6.7M−$8.2M−$5.1M$10.3M$3.8M−$1.2M$2.7M−$613,000−$3.4M
Cash from operating activities−$163.6M−$150.1M−$133.9M−$108.8M$92.6M−$80.4M−$53.0M−$28.3M−$131.2M−$117.3M
Investing activities
Capital expenditures−$138,000−$298,000−$2.8M−$464,000−$575,000−$196,000−$555,000−$1.8M−$3.6M−$16.6M
Investments (net)—−$298,000−$1.4M−$464,000−$575,000−$196,000−$547,000−$1.7M−$3.5M−$16.6M
Acquisitions & other investing$0$298,000$1.4M$464,000$575,000$196,000$555,000$1.8M$3.6M$16.6M
Cash from investing activities−$138,000−$298,000−$2.8M−$464,000−$575,000−$196,000−$547,000−$1.7M−$3.5M−$16.6M
Financing activities
Dividends paid————————$0$0
Share repurchases & issuance (net)−$139,000−$353,000——$93.6M$215,000$228,000$44.4M$168.2M$139.3M
Net borrowing (repayment)———————−$4.4M−$2.8M−$169,000
Shares issued$0$0$232.8M$223.6M$174.8M$78.4M$0$39.8M$0$0
Other financing$0$1.9M−$187.7M$17.8M−$78.0M−$78.4M$0−$39.8M$0$15.2M
Cash from financing activities−$139,000$1.6M$45.1M$241.5M$190.3M$215,000$228,000$40.0M$165.4M$154.3M
Summary
Net change in cash−$163.9M−$148.8M−$91.6M$132.2M$282.4M−$80.3M−$53.3M$10.0M$30.7M$20.4M
Cash at end of period$308.4M$472.2M$621.0M$712.6M$580.4M$298.1M$378.4M$431.7M$421.7M$391.0M
Free cash flow−$163.7M−$150.3M−$136.7M−$109.3M$92.0M−$80.6M−$53.5M−$30.0M−$134.8M−$133.9M
Free cash flow margin−1,690.6%−111.2%−149.6%−202.7%45.9%−9,444.1%−6,575.4%−3,146.0%−489.9%−12,693.2%
Capex / revenue1.4%0.2%3.1%0.9%0.3%23.0%68.2%185.1%13.2%1,577.6%
Operating cash flow / net income————1.38—————

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

PRTA cash generation

In fiscal 2025 (ended December 31, 2025), Prothena generated -$163.6 million of cash from operations and spent $0.1 million on capital expenditures, leaving free cash flow of -$163.7 million, −1,690.6% of revenue. It returned $0.1 million to shareholders through dividends ($0) and net share buybacks ($0.1 million). Cash and equivalents fell by $163.9 million over the year.

Related: PRTA income statement, PRTA balance sheet. See the PRTA stock overview for the latest quote and news.

PRTA cash flow FAQ

What is Prothena's free cash flow?

Prothena's free cash flow was -$163.7 million in fiscal 2025: -$163.6 million of operating cash flow minus $0.1 million of capital expenditures It was -$150.3 million a year earlier..

How much cash does Prothena generate from operations?

Prothena generated -$163.6 million of cash from operating activities in fiscal 2025.

How much does Prothena spend on capital expenditures?

Prothena spent $0.1 million on capital expenditures in fiscal 2025, 1.4% of revenue, compared with $0.3 million the year before.

How much stock does Prothena buy back?

Prothena spent $0.1 million on net share repurchases in fiscal 2025.

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