Puma Biotechnology, Inc. (PBYI) Ownership

NASDAQ: PBYITop holders, insider trades and short interest.

PBYI ownership summary

as of October 18, 2026
Institutions
75.6%
of shares outstanding
Insiders
15.37%
of shares outstanding
Shares outstanding
51.6M
Float
40.3M
shares available to trade
Short interest
9.68%
4.3M shares short
Days to cover
13.84
short interest down 1.3% vs prior month
  • Institutions 75.57%
  • Insiders 15.37%
  • Other investors 9.07%

PBYI top institutional holders

20 largest
Puma Biotechnology, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1BlackRock Inc7.37%3.8M$37.4M+205,784 (+5.7%)June 30, 2026
2American Century Companies Inc4.49%2.3M$22.8M+403,650 (+21.1%)June 30, 2026
3Acadian Asset Management LLC3.98%2.1M$20.2M+11,764 (+0.6%)June 30, 2026
4Renaissance Technologies Corp3.56%1.8M$18.0M−106,200 (−5.5%)June 30, 2026
5Vanguard Capital Management, LLC3.56%1.8M$18.0M+17,962 (+1.0%)June 30, 2026
6Vanguard Portfolio Management, LLC3.54%1.8M$17.9M+90,950 (+5.2%)June 30, 2026
7LSV Asset Management3.13%1.6M$15.9M+435,113 (+36.8%)June 30, 2026
8Dimensional Fund Advisors, Inc.2.94%1.5M$14.9M+81,908 (+5.7%)June 30, 2026
9Geode Capital Management, LLC2.59%1.3M$13.2M+322,063 (+31.7%)June 30, 2026
10O'Shaughnessy Asset Management LLC2.18%1.1M$11.0M−14,386 (−1.3%)June 30, 2026
11State Street Corp1.84%952K$9.4M+34,575 (+3.8%)June 30, 2026
12Kennedy Capital Management Inc1.69%873K$8.6M−16,348 (−1.8%)June 30, 2026
13Bridgeway Capital Management, LLC1.53%792K$7.8M+16,275 (+2.1%)June 30, 2026
14Comprehensive Portfolio Management, LLC1.45%750K$7.4M−24,510 (−3.2%)June 30, 2026
15AQR Capital Management LLC1.40%725K$7.1M−75,002 (−9.4%)June 30, 2026
16The Goldman Sachs Group Inc1.30%669K$6.6M−563 (−0.1%)June 30, 2026
17Northern Trust Corp1.26%652K$6.4M+10,633 (+1.7%)June 30, 2026
18Connor Clark & Lunn Inv Mgmt Ltd1.25%643K$6.3M−139,852 (−17.9%)June 30, 2026
19UBS Group AG1.23%637K$6.3M+102,534 (+19.2%)June 30, 2026
20Millennium Management LLC1.17%602K$5.9M−875,279 (−59.2%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 12 holders added 1.7M shares and 8 cut 1.3M.

PBYI top mutual fund and ETF holders

20 largest
Puma Biotechnology, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Avantis US Small Cap Value ETF4.63%2.4M$23.5M+4,200 (+0.2%)September 30, 2026
2Vanguard MStar Total Stk Mkt Idx Invest2.60%1.3M$13.2M—August 31, 2026
3iShares Russell 2000 ETF2.29%1.2M$11.6M−13,632 (−1.1%)September 30, 2026
4Vanguard Explorer Inv1.51%777K$7.6M—June 30, 2026
5Vanguard Strategic Equity Inv1.05%540K$5.3M—June 30, 2026
6Fidelity Small Cap Index0.94%484K$4.8M+6,056 (+1.3%)July 31, 2026
7iShares Russell 2000 Value ETF0.70%362K$3.6M+548 (+0.2%)September 30, 2026
8Northern Small Cap Value0.52%268K$2.6M—June 30, 2026
9Vanguard Russell 2000 ETF0.50%257K$2.5M+2,818 (+1.1%)September 30, 2026
10Russell Inv Tax-Managed US Mid&Sm Cap S0.48%248K$2.4M—August 31, 2026
11EA Bridgeway Omni Small-Cap Value ETF0.47%243K$2.4M—September 30, 2026
12DFA US Targeted Value I0.46%236K$2.3M+14,652 (+6.6%)August 31, 2026
13EA Bridgeway Select Small-Cap Value ETF0.45%231K$2.3M—September 30, 2026
14Invesco Dorsey Wright SmallCap Momt ETF0.45%231K$2.3M−615 (−0.3%)September 30, 2026
15DFA US Small Cap I0.43%221K$2.2M—August 31, 2026
16Fidelity Enhanced Small Cap Core ETF0.41%212K$2.1M+441 (+0.2%)September 30, 2026
17BlackRock Advantage Small Cap Core Instl0.40%206K$2.0M—August 31, 2026
18LSV Small Cap Value Institutional0.39%202K$2.0M+43,264 (+27.3%)September 30, 2026
19Bridgeway Ultra-Small Company0.34%173K$1.7M—June 30, 2026
20First Trust Dow Jones Sel MicroCap ETF0.33%172K$1.7M—September 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

PBYI insider transactions

latest 16
Puma Biotechnology, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-01-07Alan H AuerbachSell$5.8818,012$105,911
2026-01-07Douglas M HuntSell$5.885,014$29,482
2026-01-06Alan H AuerbachSell$5.8416,938$98,918
2026-01-06Douglas M HuntSell$5.843,973$23,202
2025-11-11Michael Patrick MillerSell$4.8620,000$97,200
2025-07-18Alessandra CesanoSell$3.3727,000$90,990
2025-07-09Alan H AuerbachSell$3.5421,580$76,393
2025-07-09Douglas M HuntSell$3.543,443$12,188
2025-07-08Alan H AuerbachSell$3.5325,592$90,340
2025-07-08Douglas M HuntSell$3.534,374$15,440
2025-06-13Adrian SenderowiczSell$3.4027,000$91,800
2025-06-13Alessandra CesanoSell$3.4012,150$41,310
2025-06-13Allison DorvalSell$3.4011,610$39,474
2025-06-13Brian M StuglikSell$3.398,100$27,459
2025-06-13Jay M MoyesSell$3.4022,000$74,800
2025-06-13Troy Edward WilsonSell$3.4010,800$36,720

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

PBYI shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns PBYI

Institutional investors own 75.6% of Puma Biotechnology's shares and insiders 15.37%. The largest holder is BlackRock Inc with 7.37% of the shares (3.8M), as of June 30, 2026. Among the top 20 institutions, 12 added shares and 8 reduced their stake in the latest filings. Short interest is 9.68% of the float, or 13.84 days of average trading volume. The share count rose 70.4% since 2014.

Related: PBYI analyst forecast, PBYI key metrics. See the PBYI stock overview for the latest quote and news.

PBYI ownership FAQ

Who owns the most Puma Biotechnology stock?

The largest shareholders of Puma Biotechnology are BlackRock Inc (7.37%), American Century Companies Inc (4.49%), Acadian Asset Management LLC (3.98%), Renaissance Technologies Corp (3.56%), Vanguard Capital Management, LLC (3.56%).

What percentage of Puma Biotechnology is owned by institutions?

Institutions hold 75.6% of Puma Biotechnology's shares outstanding; insiders hold 15.37%.

Which funds own Puma Biotechnology?

The largest fund holders of Puma Biotechnology are Avantis US Small Cap Value ETF (4.63%), Vanguard MStar Total Stk Mkt Idx Invest (2.60%), iShares Russell 2000 ETF (2.29%), Vanguard Explorer Inv (1.51%), Vanguard Strategic Equity Inv (1.05%).

What is Puma Biotechnology's short interest?

4.3M shares of Puma Biotechnology were sold short, 9.68% of the float; at the average daily volume it would take 13.84 days to cover.

Are insiders buying or selling Puma Biotechnology?

Of the latest 16 reported insider transactions in Puma Biotechnology (since June 13, 2025), 0 were purchases and 16 were sales.

How many shares of Puma Biotechnology are outstanding?

Puma Biotechnology has 51.6M shares outstanding, of which 40.3M are in the public float.

Biotechnology: ownership