OptimizeRx Corporation (OPRX) Ownership

NASDAQ: OPRXTop holders, insider trades and short interest.

OPRX ownership summary

as of October 18, 2026
Institutions
68.6%
of shares outstanding
Insiders
13.82%
of shares outstanding
Shares outstanding
18.8M
Float
14.5M
shares available to trade
Short interest
6.21%
1.1M shares short
Days to cover
7.18
short interest up 10.6% vs prior month
  • Institutions 68.61%
  • Insiders 13.82%
  • Other investors 17.57%

OPRX top institutional holders

20 largest
OptimizeRx Corporation top institutional holders
#Holder% of sharesSharesValueChangeReported
1Whetstone Capital Advisors, LLC8.01%1.5M$12.8M—June 30, 2026
2Royce & Associates, LP5.78%1.1M$9.3M+201,368 (+22.7%)June 30, 2026
3Vanguard Capital Management, LLC3.71%700K$5.9M+14,155 (+2.1%)June 30, 2026
4Kennedy Capital Management Inc3.42%644K$5.5M−12,108 (−1.8%)June 30, 2026
5Rice Hall James & Associates, LLC3.37%634K$5.4M+31,921 (+5.3%)June 30, 2026
6Blair William & Co3.23%608K$5.2M−7,067 (−1.1%)June 30, 2026
7AQR Capital Management LLC3.10%584K$5.0M+369,002 (+171.7%)June 30, 2026
8Dimensional Fund Advisors, Inc.2.54%478K$4.1M−85,883 (−15.2%)June 30, 2026
9BlackRock Inc2.36%445K$3.8M−718,119 (−61.7%)June 30, 2026
10Parkman Healthcare Partners LLC1.86%350K$3.0M−379,022 (−52.0%)June 30, 2026
11Awm Investment Company Inc1.28%240K$2.0M+10,000 (+4.3%)June 30, 2026
12Bullseye Asset Management LLC1.20%227K$1.9M+20,000 (+9.7%)March 31, 2026
13Geode Capital Management, LLC1.10%207K$1.8M−184,784 (−47.1%)June 30, 2026
14Vanguard Portfolio Management, LLC0.90%170K$1.4M−161,499 (−48.8%)June 30, 2026
15Renaissance Technologies Corp0.89%168K$1.4M−49,156 (−22.7%)June 30, 2026
16Marshall Wace Asset Management Ltd0.86%162K$1.4M+130,900 (+418.4%)June 30, 2026
17P.a.w. Capital Corp0.85%160K$1.4M+70,000 (+77.8%)June 30, 2026
18Citadel Advisors Llc0.84%158K$1.3M+157,992 (0.0%)June 30, 2026
19Morgan Stanley - Brokerage Accounts0.83%156K$1.3M+79,946 (+104.7%)June 30, 2026
20Mink Brook Asset Management LLC0.75%141K$1.2M+141,235 (0.0%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 11 holders added 1.2M shares and 8 cut 1.6M.

OPRX top mutual fund and ETF holders

20 largest
OptimizeRx Corporation top fund holders
#Holder% of sharesSharesValueChangeReported
1Royce Small-Cap Opportunity Invmt3.57%672K$5.7M+162,253 (+31.8%)September 30, 2026
2FTGF RY US SmCp Opp A USD Dis(A)3.35%631K$5.4M+45,383 (+7.8%)August 31, 2026
3Vanguard MStar Total Stk Mkt Idx Invest2.62%494K$4.2M—August 31, 2026
4Jacob Internet Inv1.83%344K$2.9M+61,000 (+21.5%)June 30, 2026
5DFA US Small Cap Value I1.22%229K$2.0M—August 31, 2026
6Fidelity Extended Market Index0.51%97K$820,326−3,509 (−3.5%)August 31, 2026
7PV BUYBACK USA Classe B USD0.47%89K$758,200—June 30, 2026
8Jacob Discovery Fd Instl0.47%89K$757,809+12,000 (+15.6%)June 30, 2026
9Dimensional US Small Cap Value ETF0.43%81K$686,562—September 24, 2026
10Vanguard Explorer Inv0.42%79K$670,854—June 30, 2026
11Jacob Small Cap Growth Investor0.36%67K$568,948+13,000 (+24.1%)June 30, 2026
12Exemplar Growth and Income Ser FD0.35%66K$561,000—September 30, 2026
13Vanguard US Multifactor ETF0.30%57K$486,566—June 30, 2026
14iShares Micro-Cap ETF0.28%52K$445,230−361 (−0.7%)September 30, 2026
15iShares Core S&P Total US Stock Mkt ETF0.24%46K$391,960+40 (+0.1%)September 30, 2026
16AQR Small Cap Multi-Style I0.24%45K$378,607+38,546 (+642.9%)June 30, 2026
17Vanguard VIF Small Co Gr0.18%33K$283,654—June 30, 2026
18Fidelity Total Market Index0.15%29K$246,908—August 31, 2026
19Fidelity Series Total Market Index0.13%25K$212,653—August 31, 2026
20DFA US Micro Cap I0.12%23K$192,380—August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

OPRX insider transactions

latest 3
OptimizeRx Corporation insider transactions
DateNameTransactionPriceSharesValue
2025-12-19Edward StelmakhSell$13.511,388$18,752
2025-10-03Stephen L SilvestroSell$18.751,620$30,375
2025-08-28Patrick D SpanglerSell$17.4911,120$194,489

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

OPRX shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns OPRX

Institutional investors own 68.6% of OptimizeRx's shares and insiders 13.82%. The largest holder is Whetstone Capital Advisors, LLC with 8.01% of the shares (1.5M), as of June 30, 2026. Among the top 20 institutions, 11 added shares and 8 reduced their stake in the latest filings. Short interest is 6.21% of the float, or 7.18 days of average trading volume. The share count rose 153.9% since 2014.

Related: OPRX analyst forecast, OPRX key metrics. See the OPRX stock overview for the latest quote and news.

OPRX ownership FAQ

Who owns the most OptimizeRx stock?

The largest shareholders of OptimizeRx are Whetstone Capital Advisors, LLC (8.01%), Royce & Associates, LP (5.78%), Vanguard Capital Management, LLC (3.71%), Kennedy Capital Management Inc (3.42%), Rice Hall James & Associates, LLC (3.37%).

What percentage of OptimizeRx is owned by institutions?

Institutions hold 68.6% of OptimizeRx's shares outstanding; insiders hold 13.82%.

Which funds own OptimizeRx?

The largest fund holders of OptimizeRx are Royce Small-Cap Opportunity Invmt (3.57%), FTGF RY US SmCp Opp A USD Dis(A) (3.35%), Vanguard MStar Total Stk Mkt Idx Invest (2.62%), Jacob Internet Inv (1.83%), DFA US Small Cap Value I (1.22%).

What is OptimizeRx's short interest?

1.1M shares of OptimizeRx were sold short, 6.21% of the float; at the average daily volume it would take 7.18 days to cover.

Are insiders buying or selling OptimizeRx?

Of the latest 3 reported insider transactions in OptimizeRx (since August 28, 2025), 0 were purchases and 3 were sales.

How many shares of OptimizeRx are outstanding?

OptimizeRx has 18.8M shares outstanding, of which 14.5M are in the public float.

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