Omeros Corporation (OMER) Ownership

NASDAQ: OMERTop holders, insider trades and short interest.

OMER ownership summary

as of October 18, 2026
Institutions
51.4%
of shares outstanding
Insiders
4.08%
of shares outstanding
Shares outstanding
72.4M
Float
69.3M
shares available to trade
Short interest
16.30%
11.4M shares short
Days to cover
7.54
short interest down 8.9% vs prior month
  • Institutions 51.36%
  • Insiders 4.08%
  • Other investors 44.55%

OMER top institutional holders

20 largest
Omeros Corporation top institutional holders
#Holder% of sharesSharesValueChangeReported
1BlackRock Inc8.35%6.0M$97.9M+735,007 (+13.8%)June 30, 2026
2Ingalls & Snyder LLC5.06%3.7M$59.3M+100,100 (+2.8%)June 30, 2026
3UBS Group AG4.35%3.1M$51.0M+807,653 (+34.5%)June 30, 2026
4Vanguard Capital Management, LLC4.24%3.1M$49.8M+88,791 (+3.0%)June 30, 2026
5State Street Corp3.20%2.3M$37.6M+400,331 (+20.9%)June 30, 2026
6Geode Capital Management, LLC2.64%1.9M$31.0M+162,137 (+9.3%)June 30, 2026
7Stifel Financial Corp2.54%1.8M$29.8M+5,340 (+0.3%)June 30, 2026
8Vanguard Portfolio Management, LLC1.33%963K$15.6M+244,153 (+34.0%)June 30, 2026
9Amvescap Plc.1.04%752K$12.2M+571,142 (+316.2%)June 30, 2026
10Northern Trust Corp1.00%727K$11.8M+163,481 (+29.0%)June 30, 2026
11Rock Springs Capital Management LP0.99%718K$11.6M+718,499 (0.0%)June 30, 2026
12CI Private Wealth LLC0.91%660K$10.7M−141,681 (−17.7%)June 30, 2026
13Rubric Capital Management LP0.91%657K$10.6M+656,874 (0.0%)June 30, 2026
14Charles Schwab Investment Management Inc0.84%605K$9.8M+22,121 (+3.8%)June 30, 2026
15Bank of Montreal0.79%568K$9.2M−2 (−0.0%)June 30, 2026
16BMO Capital Markets Corp.0.79%568K$9.2M−2 (−0.0%)June 30, 2026
17Vanguard Fiduciary Trust Co0.68%491K$8.0M−1,172 (−0.2%)June 30, 2026
18Federated Hermes Inc0.66%478K$7.7M+478,290 (0.0%)June 30, 2026
19Clutterbuck Capital Management LLC0.62%450K$7.3M+150,000 (+50.0%)June 30, 2026
20Two Sigma Investments LLC0.56%403K$6.5M+116,188 (+40.6%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 16 holders added 5.4M shares and 4 cut 143K.

OMER top mutual fund and ETF holders

20 largest
Omeros Corporation top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest3.00%2.2M$35.2M—August 31, 2026
2iShares Russell 2000 ETF2.58%1.9M$30.2M−21,504 (−1.1%)September 30, 2026
3Fidelity Small Cap Index1.09%789K$12.8M+7,440 (+1.0%)July 31, 2026
4State Street® SPDR® S&P® PhrmctlsETF0.74%537K$8.7M−6,674 (−1.2%)September 30, 2026
5iShares Russell 2000 Value ETF0.58%420K$6.8M+636 (+0.2%)September 30, 2026
6Vanguard Russell 2000 ETF0.58%419K$6.8M+4,958 (+1.2%)September 30, 2026
7Schwab US Small-Cap ETF™0.53%383K$6.2M+252 (+0.1%)September 30, 2026
8Fidelity Extended Market Index0.49%352K$5.7M−5,520 (−1.5%)August 31, 2026
9Vanguard US Momentum Factor ETF0.37%268K$4.3M+166,334 (+164.2%)June 30, 2026
10iShares US Pharmaceuticals ETF0.36%264K$4.3M+811 (+0.3%)September 30, 2026
11iShares Russell 2000 Growth ETF0.35%255K$4.1M−323 (−0.1%)September 30, 2026
12iShares Micro-Cap ETF0.31%228K$3.7M−1,570 (−0.7%)September 30, 2026
13Vanguard Health Care ETF0.29%211K$3.4M+228 (+0.1%)September 30, 2026
14Heptagon Driehaus US Micro Cap Eq C$ Acc0.29%207K$3.4M+207,321 (0.0%)August 31, 2026
15Federated Hermes MDT Small Cap Growth IS0.27%193K$3.1M+193,492 (0.0%)June 30, 2026
16Virtus LifeSci Biotech Products ETF0.27%193K$3.1M—September 30, 2026
17Schwab Small Cap Index0.24%175K$2.8M—August 31, 2026
18Fidelity Total Market Index0.19%140K$2.3M+5,997 (+4.5%)August 31, 2026
19iShares Russell 2000 Small-Cap Idx Instl0.19%135K$2.2M—August 31, 2026
20Stt Strt SPDR® Russell2000 US SmCapETF0.18%132K$2.1M−9,184 (−6.5%)September 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

OMER insider transactions

latest 1
Omeros Corporation insider transactions
DateNameTransactionPriceSharesValue
2026-01-13David J BorgesSell$12.3130,000$369,300

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

OMER shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns OMER

Institutional investors own 51.4% of Omeros's shares and insiders 4.08%. The largest holder is BlackRock Inc with 8.35% of the shares (6.0M), as of June 30, 2026. Among the top 20 institutions, 16 added shares and 4 reduced their stake in the latest filings. Short interest is 16.30% of the float, or 7.54 days of average trading volume. The share count rose 86.2% since 2014.

Related: OMER analyst forecast, OMER key metrics. See the OMER stock overview for the latest quote and news.

OMER ownership FAQ

Who owns the most Omeros stock?

The largest shareholders of Omeros are BlackRock Inc (8.35%), Ingalls & Snyder LLC (5.06%), UBS Group AG (4.35%), Vanguard Capital Management, LLC (4.24%), State Street Corp (3.20%).

What percentage of Omeros is owned by institutions?

Institutions hold 51.4% of Omeros's shares outstanding; insiders hold 4.08%.

Which funds own Omeros?

The largest fund holders of Omeros are Vanguard MStar Total Stk Mkt Idx Invest (3.00%), iShares Russell 2000 ETF (2.58%), Fidelity Small Cap Index (1.09%), State Street® SPDR® S&P® PhrmctlsETF (0.74%), iShares Russell 2000 Value ETF (0.58%).

What is Omeros's short interest?

11.4M shares of Omeros were sold short, 16.30% of the float; at the average daily volume it would take 7.54 days to cover.

Are insiders buying or selling Omeros?

Of the latest 1 reported insider transactions in Omeros (since January 13, 2026), 0 were purchases and 1 were sales.

How many shares of Omeros are outstanding?

Omeros has 72.4M shares outstanding, of which 69.3M are in the public float.

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