Omeros Corporation (OMER) Key Metrics

NASDAQ: OMERValuation, returns, debt and efficiency ratios over 10 years.

OMER valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$1.17B
Enterprise value
$1.53B
P/E (TTM)
13.3
Forward P/E
87.7
PEG ratio
0.81
Price / sales
30.5
10-yr median 10.4
Price / book
8.4
10-yr median 1.7
EV / EBITDA
163.7
Dividend yield
—
Beta
2.57

OMER key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

OMER valuation Price multiples at each fiscal year-end price.

Free cash flow yield+15.3 pts
−10.6%
2025 · hover or tap a bar for each year
2016: −12.9% (−1.8 pts)2017: −4.1% (+8.7 pts)2018: −19.3% (−15.1 pts)2019: −8.7% (+10.6 pts)2020: −12.3% (−3.6 pts)2021: −27.4% (−15.2 pts)2022: −61.1% (−33.6 pts)2023: 36.2% (+97.3 pts)2024: −25.9% (−62.1 pts)2025: −10.6% (+15.3 pts)
20162025

OMER valuation history

Fiscal year-endToday10-year median

OMER returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

OMER debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

OMER cash returned to shareholders

DividendsBuybacksFree cash flow

OMER price vs earnings per share

Share price at year-endEPS (right axis)

OMER key metrics

2016–2025
Omeros Corporation key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$1.09B$574.7M$205.2M$141.8M$400.9M$816.8M$697.8M$541.2M$884.8M$401.2M
Enterprise value$1.16B$691.6M$394.9M$288.9M$591.4M$921.9M$798.7M$632.2M$885.7M$435.9M
P/E ratio———3.0——————
Price / sales————4.411.16.218.113.69.6
Price / book———1.716.9——0.8——
Price / free cash flow——2.8———————
Price / operating cash flow——2.7———————
EV / sales————6.512.57.121.213.710.5
EV / free cash flow——5.3———————
Earnings yield−0.3%−27.3%−57.4%33.4%−27.8%−16.9%−12.1%−23.4%−6.0%−16.6%
Free cash flow yield−10.6%−25.9%36.2%−61.1%−27.4%−12.3%−8.7%−19.3%−4.1%−12.9%
Dividend yield————————0.0%0.0%
Shareholder yield (dividends + buybacks)0.0%2.1%2.3%0.0%0.0%0.0%0.0%0.0%0.0%0.0%
Share price at fiscal year-end$17.18$9.88$3.27$2.26$6.43$14.29$14.09$11.14$19.43$9.92
Per share
Revenue per share$0.00$0.00$0.00$0.00$1.45$1.29$2.26$0.61$1.42$1.03
Earnings per share−$0.05−$2.70−$1.88$0.76−$1.79−$2.41−$1.71−$2.61−$1.17−$1.65
Operating cash flow per share−$1.83−$2.56$1.19−$1.38−$1.76−$1.75−$1.21−$2.14−$0.80−$1.27
Free cash flow per share−$1.83−$2.56$1.18−$1.38−$1.76−$1.76−$1.22−$2.15−$0.80−$1.28
Cash per share$2.71$1.55$2.74$3.11$2.52$2.36$1.23$1.25$1.84$1.12
Book value per share−$1.91−$3.14−$0.40$1.37$0.38−$2.11−$2.20$13.38−$0.06−$0.93
Tangible book value per share−$1.91−$3.14−$0.40$1.37$0.38−$2.11−$2.20$13.38−$0.06−$0.93
Dividends per share————————$0.00$0.00
Capex per share$0.00$0.00$0.01$0.00$0.00$0.00$0.01$0.01$0.01$0.00
Debt per share$3.77$3.56$5.76$5.45$5.58$4.20$3.27$3.12$1.86$1.98
Shares outstanding63.5M58.2M62.7M62.7M62.3M57.2M49.5M48.6M45.5M40.4M
Change in shares outstanding+9.2%−7.3%+0.0%+0.6%+9.0%+15.5%+1.9%+6.7%+12.6%+7.7%
Returns & profitability
Return on equity (ROE)———86.6%———−39.2%——
Return on invested capital (ROIC)——−65.4%−57.7%−138.0%——−24.0%——
Return on assets (ROA)−1.1%−47.9%−24.3%9.4%−37.1%−86.8%−72.5%−119.4%−58.3%−114.8%
Return on tangible assets−1.0%−56.6%−31.1%8.0%−26.6%−76.3%−61.7%−132.1%−46.0%−99.2%
Free cash flow margin————−121.5%−136.0%−54.0%−349.2%−56.4%−124.1%
Income quality (OCF / net income)———−1.82——————
Financial health
Total debt$239.1M$207.0M$361.6M$342.0M$347.8M$240.1M$161.7M$151.4M$84.6M$80.0M
Cash & short-term investments$171.8M$90.1M$171.8M$194.9M$157.3M$135.0M$60.8M$60.5M$83.7M$45.3M
Net debt$67.3M$116.9M$189.7M$147.1M$190.6M$105.1M$100.9M$91.0M$858,000$34.7M
Debt / equity———3.9914.63——0.23——
Debt / assets0.730.750.960.580.831.331.181.580.731.19
Current ratio2.761.694.093.254.794.121.872.414.123.75
Quick ratio2.761.693.933.254.791.001.001.004.103.68
Interest coverage-127.9-6.9-5.3-7.2-8.8-5.9-2.8-6.9-4.0-6.9
Working capital$137.6M$54.6M$164.6M$306.9M$196.2M$114.5M$48.3M$52.5M$82.1M$44.2M
Invested capital−$53.9M−$65.7M$164.8M$232.8M$214.4M−$15.6M−$8.1M$741.1M−$2.0M−$2.7M
Tangible asset value−$121.2M−$182.6M−$25.0M$85.7M$23.8M−$120.8M−$109.0M$100.2M−$2.8M−$37.4M
Net current asset value−$231.2M−$325.6M−$185.4M−$62.0M−$147.5M−$150.5M−$142.2M$94.1M−$10.8M−$44.5M
Graham number———$4.82——————
Graham net-net per share−$3.90−$5.88−$3.54−$2.05−$2.83−$1.87−$2.72$2.22−$0.49−$1.23
Capital allocation
Dividends paid————————$0$0
Share buybacks (net)$0$11.9M$4.7M$0$0$0$0$0$0$0
Dividends + buybacks / free cash flow——6.3%———————
Capex / revenue————0.3%0.4%0.3%1.9%0.5%0.3%
Capex / operating cash flow——0.6%———————
Capex / depreciation0.070.170.460.120.200.180.190.590.640.42
Stock-based compensation / revenue————19.5%20.2%12.3%39.2%19.6%32.6%
R&D / revenue————131.2%145.8%98.1%300.9%85.8%121.8%
SG&A / revenue————60.6%98.5%57.8%173.2%80.7%105.2%
Efficiency
Days sales outstanding————174.096.594.7244.282.281.4
Days of inventory on hand——44.9——18,389.56,928.618,875.2266.0206.8
Days payables outstanding—2,615.935.83,716.92,317.31,075.9798.04,623.81,559.21,156.4
Cash conversion cycle (days)————12,939.817,410.06,225.314,495.6-1,211.1-868.2
Receivables turnover0.000.000.000.002.103.783.861.494.444.49
Payables turnover—0.1410.190.100.160.340.460.080.230.32
Inventory turnover——8.13——0.020.050.021.371.76
Asset turnover0.000.000.000.000.300.460.960.280.710.72
Average receivables$36.5M$21.8M$124.4M$162.2M$43.2M$19.5M$29.0M$20.0M$14.6M$9.3M
Average payables$5.3M$6.8M$6.9M$9.7M$8.8M$4.8M$5.8M$6.5M$4.6M$4.5M
Average inventory——$8.6M—$57.3M$81.4M$50.4M$26.5M$785,500$800,000
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%

Computed from OMER's annual financial statements (latest annual report filed March 31, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

OMER valuation and financial ratios

Based on the latest twelve months, the trailing P/E is 13.3 and the forward P/E is 87.7. It ended the year with $239.1 million of debt and $171.8 million in cash and short-term investments, net debt of $67.3 million. The share count rose 57.0% from 40.4M to 63.5M over 9 years.

See the OMER income statement, the OMER chart for price history, or the OMER stock overview for the latest quote and news.

OMER key metrics FAQ

What is Omeros's P/E ratio?

Omeros's trailing P/E ratio is 13.3 based on the last twelve months of earnings (as of October 18, 2026), and its forward P/E is 87.7. At the end of fiscal 2025 it was —.

How much debt does Omeros have?

Omeros had total debt of $239.1 million at the end of fiscal 2025.

What is Omeros's free cash flow yield?

Omeros generated -$116.2 million of free cash flow in fiscal 2025, a free cash flow yield of −10.6% on its market value at year-end ($1.1 billion).

What is Omeros's current ratio?

Omeros's current ratio was 2.76 at the end of fiscal 2025: current assets were 2.76 times current liabilities.

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