Lexeo Therapeutics, Inc. (LXEO) Ownership

NASDAQ: LXEOTop holders, insider trades and short interest.

LXEO ownership summary

as of October 18, 2026
Institutions
114.8%
of shares outstanding
Insiders
0.64%
of shares outstanding
Shares outstanding
82.1M
Float
51.2M
shares available to trade
Short interest
27.35%
19.2M shares short
Days to cover
13.91
short interest down 6.7% vs prior month
  • Institutions 114.80%
  • Insiders 0.64%

LXEO top institutional holders

20 largest
Lexeo Therapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1Suvretta Capital Management, LLC7.78%6.4M$16.9M+5.1M (+410.7%)June 30, 2026
2Affinity Asset Advisors, LLC7.07%5.8M$15.3M+757,400 (+15.0%)June 30, 2026
3BlackRock Inc6.99%5.7M$15.2M+628,584 (+12.3%)June 30, 2026
4RA Capital Management, LLC6.09%5.0M$13.2M—June 30, 2026
5HHG PLC6.06%5.0M$13.1M−533,206 (−9.7%)March 31, 2026
6Frazier Life Sciences Management, L.P.5.88%4.8M$12.7M+400,000 (+9.0%)June 30, 2026
7State Street Corp5.30%4.4M$11.5M+786,515 (+22.0%)June 30, 2026
8Vestal Point Capital LP5.26%4.3M$11.4M−155,000 (−3.5%)June 30, 2026
9Paradigm Biocapital Advisors LP5.09%4.2M$11.0M−2.0M (−32.5%)June 30, 2026
10Jupiter Topco LLC4.82%4.0M$10.4M+4.0M (0.0%)June 30, 2026
11Orbimed Advisors LLC4.81%3.9M$10.4M+345,400 (+9.6%)June 30, 2026
12Citadel Advisors Llc4.75%3.9M$10.3M+63,571 (+1.7%)June 30, 2026
13Vanguard Capital Management, LLC3.81%3.1M$8.3M+118,800 (+4.0%)June 30, 2026
14Millennium Management LLC3.45%2.8M$7.5M+1.2M (+75.7%)June 30, 2026
15Nantahala Capital Management, LLC3.17%2.6M$6.9M+1.4M (+116.7%)June 30, 2026
16Woodline Partners LP3.05%2.5M$6.6M−250,000 (−9.1%)June 30, 2026
17Balyasny Asset Management LLC2.94%2.4M$6.4M+823,157 (+51.8%)June 30, 2026
18The Goldman Sachs Group Inc2.62%2.1M$5.7M+199,727 (+10.2%)June 30, 2026
19Geode Capital Management, LLC2.13%1.7M$4.6M+234,182 (+15.5%)June 30, 2026
20ADAR1 Capital Management LLC1.91%1.6M$4.1M+98,600 (+6.7%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 15 holders added 16.2M shares and 4 cut 2.9M.

LXEO top mutual fund and ETF holders

20 largest
Lexeo Therapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.84%2.3M$6.2M—August 31, 2026
2JPMorgan Small Cap Growth A2.57%2.1M$5.6M+514,712 (+32.3%)August 31, 2026
3iShares Russell 2000 ETF2.26%1.9M$4.9M−21,376 (−1.1%)September 30, 2026
4State Street® SPDR® S&P® Biotech ETF1.94%1.6M$4.2M−30,450 (−1.9%)September 30, 2026
5abrdn Life Sciences Investors1.18%968K$2.6M+146,954 (+17.9%)August 31, 2026
6Fidelity Small Cap Index0.95%777K$2.1M+6,523 (+0.8%)July 31, 2026
7Biotech Growth Ord0.91%745K$2.0M+345,400 (+86.5%)June 30, 2026
8JPMorgan Small Cap Blend A0.82%676K$1.8M+169,006 (+33.3%)August 31, 2026
9iShares Russell 2000 Value ETF0.81%668K$1.8M+1,014 (+0.2%)September 30, 2026
10Janus Global Life Science AUSD0.70%576K$1.5M−4,551 (−0.8%)June 30, 2026
11Janus Henderson Glb Life Scn I2 USD0.70%576K$1.5M−2 (−0.0%)August 31, 2026
12Stt Strt®SPDR®S&PKenshoNwEcosComposETF0.69%564K$1.5M—September 30, 2026
13Janus Henderson Global Life Sciences D0.68%561K$1.5M—August 31, 2026
14iShares Biotechnology ETF0.66%539K$1.4M−4,088 (−0.8%)September 30, 2026
15Vanguard Russell 2000 ETF0.50%408K$1.1M+10,098 (+2.5%)August 31, 2026
16Fidelity Extended Market Index0.40%325K$857,047+92,650 (+39.9%)August 31, 2026
17Fidelity Enhanced Small Cap Core ETF0.36%294K$776,094+615 (+0.2%)September 30, 2026
18Multi-Manager Small Cap Eq Strat Inst0.35%284K$749,514+32,172 (+12.8%)August 31, 2026
19Northern Small Cap Value0.32%261K$689,328+261,109 (0.0%)June 30, 2026
20Dimensional US Small Cap ETF0.31%254K$670,695—September 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

LXEO insider transactions

latest 18
Lexeo Therapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-04-06Richard Nolan TownsendSell$5.6955,000$312,950
2026-02-18Jose Manuel OteroSell$6.403,016$19,302
2026-02-18Richard Nolan TownsendSell$6.3810,173$64,904
2025-11-18Eric AdlerSell$9.27615$5,701
2025-11-18Richard Nolan TownsendSell$9.271,127$10,447
2025-11-18Tai Sandi SeeSell$9.27386$3,578
2025-10-17Tai Sandi SeeSell$8.943,888$34,759
2025-10-17Richard Nolan TownsendSell$8.9413,133$117,409
2025-10-17Jose Manuel OteroSell$8.942,115$18,908
2025-10-17Eric AdlerSell$8.943,382$30,235
2025-08-18Eric AdlerSell$4.67608$2,839
2025-08-18Jose Manuel OteroSell$4.672,848$13,300
2025-08-18Jose Manuel OteroSell$9.27721$6,684
2025-08-18Richard Nolan TownsendSell$4.672,735$12,772
2025-08-18Tai Sandi SeeSell$4.67382$1,784
2025-05-16Eric AdlerSell$2.77585$1,620
2025-05-16Richard Nolan TownsendSell$2.771,074$2,975
2025-05-16Tai Sandi SeeSell$2.77367$1,017

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

LXEO shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns LXEO

Institutional investors own 114.8% of Lexeo Therapeutics's shares and insiders 0.64%. The largest holder is Suvretta Capital Management, LLC with 7.78% of the shares (6.4M), as of June 30, 2026. Among the top 20 institutions, 15 added shares and 4 reduced their stake in the latest filings. Short interest is 27.35% of the float, or 13.91 days of average trading volume. The share count rose 203.4% since 2022.

Related: LXEO analyst forecast, LXEO key metrics. See the LXEO stock overview for the latest quote and news.

LXEO ownership FAQ

Who owns the most Lexeo Therapeutics stock?

The largest shareholders of Lexeo Therapeutics are Suvretta Capital Management, LLC (7.78%), Affinity Asset Advisors, LLC (7.07%), BlackRock Inc (6.99%), RA Capital Management, LLC (6.09%), HHG PLC (6.06%).

What percentage of Lexeo Therapeutics is owned by institutions?

Institutions hold 114.8% of Lexeo Therapeutics's shares outstanding; insiders hold 0.64%.

Which funds own Lexeo Therapeutics?

The largest fund holders of Lexeo Therapeutics are Vanguard MStar Total Stk Mkt Idx Invest (2.84%), JPMorgan Small Cap Growth A (2.57%), iShares Russell 2000 ETF (2.26%), State Street® SPDR® S&P® Biotech ETF (1.94%), abrdn Life Sciences Investors (1.18%).

What is Lexeo Therapeutics's short interest?

19.2M shares of Lexeo Therapeutics were sold short, 27.35% of the float; at the average daily volume it would take 13.91 days to cover.

Are insiders buying or selling Lexeo Therapeutics?

Of the latest 18 reported insider transactions in Lexeo Therapeutics (since May 16, 2025), 0 were purchases and 18 were sales.

How many shares of Lexeo Therapeutics are outstanding?

Lexeo Therapeutics has 82.1M shares outstanding, of which 51.2M are in the public float.

Biotechnology: ownership