Lexeo Therapeutics, Inc. (LXEO) Cash Flow Statement

NASDAQ: LXEOOperating cash, capex, free cash flow and buybacks.

Where LXEO’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$98.6M
Capital expenditures
$397,000
Free cash flow
−$99.0M
Returned to shareholders
—
Change in cash
$28.0M
cash at year-end $66.2M
Share issuance (net): $80.0MShare issuance (net)$80.0MShares issued: $234.0MShares issued$234.0MCash used in operations: $98.6MCash used in operations$98.6M · 31%Other financing: $96.7MOther financing$96.7M · 31%Investments (net): $89.9MInvestments (net)$89.9M · 29%Added to cash: $28.0MAdded to cash$28.0M · 9%Debt repayment, Capital expenditures: $930,000Other uses$930,000 · 0%$314.0M
Cash from operations
−$98.6M
Capital expenditures
−$397,000
Investments (net)
−$89.9M
Share buybacks (net)
+$80.0M
Net borrowing (repayment)
−$533,000
Shares issued
+$234.0M
Other financing
−$96.7M
Change in cash
$28.0M

Drawn to scale: where the cash came from and how it was used. Hover for values.

LXEO operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

LXEO cash flow trends, 2020–2025

Lexeo Therapeutics, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$3.1M2020−$98.6M2025—
Capital expenditures$02020$397,0002025—
Free cash flow−$3.1M2020−$99.0M2025—
Free cash flow margin−604.3%2020−8,480.3%2022−7,875.9 pts
Stock-based compensation$02020$12.1M2025—
Share buybacks (net)$02023$02025—
Capex / revenue0.0%2020137.8%2022+137.8 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

LXEO cash flow by activity

OperatingInvestingFinancingChange in cash

LXEO net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

LXEO cash flow statement

Lexeo Therapeutics, Inc. annual cash flow statement
202520242023202220212020
Operating activities
Net income−$100.0M−$98.3M−$66.4M−$59.3M−$50.6M−$5.2M
Depreciation & amortization$2.1M$2.0M$1.8M$1.1M$13,000$0
Stock-based compensation$12.1M$12.5M$3.0M$1.8M$386,000$0
Change in working capital−$9.5M$2.7M$1.5M$1.8M$6.0M$150,151
Other non-cash items−$3.3M−$23,000$530,000$0$0$1.9M
Cash from operating activities−$98.6M−$81.2M−$59.5M−$54.6M−$44.2M−$3.1M
Investing activities
Capital expenditures−$397,000−$481,000−$165,000−$901,000−$188,000$0
Investments (net)−$89.9M−$94.1M−$165,000−$901,000−$188,000$0
Acquisitions & other investing$0$481,000$165,000$901,000$188,000—
Cash from investing activities−$90.3M−$94.1M−$165,000−$901,000−$188,000—
Financing activities
Share repurchases & issuance (net)$80.0M−$17,000$0———
Net borrowing (repayment)−$533,000−$410,000$3.6M−$163,000$0—
Shares issued$234.0M$88.7M$100.3M$20,000$151.1M$30.0M
Other financing−$96.7M$491,000−$35,000$332,000−$203,000$2.4M
Cash from financing activities$216.8M$88.8M$103.8M$189,000$150.9M$32.4M
Summary
Net change in cash$28.0M−$86.5M$44.1M−$55.3M$106.5M$29.2M
Cash at end of period$66.2M$38.3M$124.7M$80.6M$135.9M$29.4M
Free cash flow−$99.0M−$81.6M−$59.7M−$55.5M−$44.4M−$3.1M
Free cash flow margin———−8,480.3%−2,677.7%−604.3%
Capex / revenue———137.8%11.3%0.0%

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

LXEO cash generation

In fiscal 2025 (ended December 31, 2025), Lexeo Therapeutics generated -$98.6 million of cash from operations and spent $0.4 million on capital expenditures, leaving free cash flow of -$99.0 million. Cash and equivalents rose by $28.0 million over the year.

Related: LXEO income statement, LXEO balance sheet. See the LXEO stock overview for the latest quote and news.

LXEO cash flow FAQ

What is Lexeo Therapeutics's free cash flow?

Lexeo Therapeutics's free cash flow was -$99.0 million in fiscal 2025: -$98.6 million of operating cash flow minus $0.4 million of capital expenditures It was -$81.6 million a year earlier..

How much cash does Lexeo Therapeutics generate from operations?

Lexeo Therapeutics generated -$98.6 million of cash from operating activities in fiscal 2025.

How much does Lexeo Therapeutics spend on capital expenditures?

Lexeo Therapeutics spent $0.4 million on capital expenditures in fiscal 2025, compared with $0.5 million the year before.

Biotechnology: cash flow