Iovance Biotherapeutics, Inc. (IOVA) Ownership

NASDAQ: IOVATop holders, insider trades and short interest.

IOVA ownership summary

as of October 18, 2026
Institutions
70.8%
of shares outstanding
Insiders
0.35%
of shares outstanding
Shares outstanding
453.0M
Float
394.3M
shares available to trade
Short interest
15.31%
64.8M shares short
Days to cover
3.69
short interest down 25.6% vs prior month
  • Institutions 70.82%
  • Insiders 0.35%
  • Other investors 28.83%

IOVA top institutional holders

20 largest
Iovance Biotherapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1BlackRock Inc8.16%37.0M$503.4M+5.9M (+18.9%)June 30, 2026
2Mhr Fund Management Llc6.39%29.0M$394.5M—June 30, 2026
3State Street Corp5.40%24.5M$333.4M+7.0M (+40.3%)June 30, 2026
4Two Sigma Investments LLC4.20%19.0M$258.9M+5.3M (+38.9%)June 30, 2026
5Vanguard Capital Management, LLC4.02%18.2M$247.9M+1.6M (+9.5%)June 30, 2026
6Vanguard Portfolio Management, LLC3.18%14.4M$196.0M+2.7M (+23.0%)June 30, 2026
7Geode Capital Management, LLC2.28%10.3M$140.6M+1.8M (+20.4%)June 30, 2026
8Millennium Management LLC1.88%8.5M$116.1M−888,373 (−9.4%)June 30, 2026
9Dimensional Fund Advisors, Inc.1.43%6.5M$88.0M+3.8M (+144.2%)June 30, 2026
10Palo Alto Investors, LLC1.17%5.3M$72.1M−1.1M (−16.6%)June 30, 2026
11The Goldman Sachs Group Inc1.13%5.1M$69.4M−3.7M (−41.8%)June 30, 2026
12Nuveen, LLC1.10%5.0M$68.1M+1.3M (+36.4%)June 30, 2026
13Bank of America Corp1.10%5.0M$68.0M−3.5M (−41.2%)June 30, 2026
14Morgan Stanley - Brokerage Accounts1.10%5.0M$67.9M−1.2M (−19.6%)June 30, 2026
15Jupiter Asset Management Limited1.00%4.5M$61.8M+4.5M (0.0%)June 30, 2026
16Jane Street Group LLC0.97%4.4M$59.8M+219,967 (+5.3%)June 30, 2026
17Northern Trust Corp0.92%4.2M$56.6M+1.3M (+44.5%)June 30, 2026
18AQR Capital Management LLC0.85%3.9M$52.7M+3.2M (+520.0%)June 30, 2026
19Wells Fargo & Co0.72%3.2M$44.2M+1.2M (+56.7%)June 30, 2026
20Charles Schwab Investment Management Inc0.71%3.2M$43.9M+435,926 (+15.7%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 14 holders added 40.3M shares and 5 cut 10.3M.

IOVA top mutual fund and ETF holders

20 largest
Iovance Biotherapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.98%13.5M$184.0M−24,258 (−0.2%)August 31, 2026
2State Street® SPDR® S&P® Biotech ETF2.50%11.3M$154.2M−215,550 (−1.9%)September 30, 2026
3iShares Russell 2000 ETF2.27%10.3M$140.2M−118,592 (−1.1%)September 30, 2026
4Vanguard Small Cap Index1.07%4.8M$66.0M−32,164 (−0.7%)September 30, 2026
5Jupiter Merian Glb Eq Abs Rt I USD Acc0.96%4.4M$59.5M+4.4M (0.0%)June 30, 2026
6Fidelity Small Cap Index0.96%4.4M$59.3M+36,563 (+0.8%)July 31, 2026
7iShares Russell 2000 Value ETF0.82%3.7M$50.8M+5,656 (+0.2%)September 30, 2026
8iShares Biotechnology ETF0.68%3.1M$41.8M−23,248 (−0.8%)September 30, 2026
9Nuveen Quant Small Cap Equity R60.60%2.7M$36.9M—August 31, 2026
10Rhenman Healthcare Equity L/S RC2 SEK0.56%2.5M$34.7M+950,000 (+59.5%)January 31, 2026
11Vanguard Russell 2000 ETF0.51%2.3M$31.5M+25,867 (+1.1%)September 30, 2026
12Schwab US Small-Cap ETF™0.46%2.1M$28.2M+1,395 (+0.1%)September 30, 2026
13Vanguard Strategic Equity Inv0.45%2.0M$27.5M+926,623 (+84.9%)June 30, 2026
14Fidelity Extended Market Index0.41%1.8M$25.1M−20,994 (−1.1%)August 31, 2026
15Vanguard MStar Small Cap Value Index0.35%1.6M$21.5M−1.5M (−49.2%)September 30, 2026
16Fidelity Enhanced Small Cap Core ETF0.33%1.5M$20.3M+3,126 (+0.2%)September 30, 2026
17T. Rowe Price Health Sciences0.32%1.4M$19.6M—September 30, 2026
18Vanguard MStar Small Cap Growth Indx Inv0.30%1.3M$18.4M+1.3M (0.0%)September 30, 2026
19DFA US Small Cap I0.30%1.3M$18.3M—August 31, 2026
20C WorldWide Healthcare Select 1A0.28%1.3M$17.2M—June 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

IOVA insider transactions

latest 1
Iovance Biotherapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2025-05-23Raj K PuriBuy$1.745,600$9,744

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

IOVA shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns IOVA

Institutional investors own 70.8% of Iovance Biotherapeutics's shares and insiders 0.35%. The largest holder is BlackRock Inc with 8.16% of the shares (37.0M), as of June 30, 2026. Among the top 20 institutions, 14 added shares and 5 reduced their stake in the latest filings. Short interest is 15.31% of the float, or 3.69 days of average trading volume. The share count rose 980.1% since 2014.

Related: IOVA analyst forecast, IOVA key metrics. See the IOVA stock overview for the latest quote and news.

IOVA ownership FAQ

Who owns the most Iovance Biotherapeutics stock?

The largest shareholders of Iovance Biotherapeutics are BlackRock Inc (8.16%), Mhr Fund Management Llc (6.39%), State Street Corp (5.40%), Two Sigma Investments LLC (4.20%), Vanguard Capital Management, LLC (4.02%).

What percentage of Iovance Biotherapeutics is owned by institutions?

Institutions hold 70.8% of Iovance Biotherapeutics's shares outstanding; insiders hold 0.35%.

Which funds own Iovance Biotherapeutics?

The largest fund holders of Iovance Biotherapeutics are Vanguard MStar Total Stk Mkt Idx Invest (2.98%), State Street® SPDR® S&P® Biotech ETF (2.50%), iShares Russell 2000 ETF (2.27%), Vanguard Small Cap Index (1.07%), Jupiter Merian Glb Eq Abs Rt I USD Acc (0.96%).

What is Iovance Biotherapeutics's short interest?

64.8M shares of Iovance Biotherapeutics were sold short, 15.31% of the float; at the average daily volume it would take 3.69 days to cover.

Are insiders buying or selling Iovance Biotherapeutics?

Of the latest 1 reported insider transactions in Iovance Biotherapeutics (since May 23, 2025), 1 were purchases and 0 were sales.

How many shares of Iovance Biotherapeutics are outstanding?

Iovance Biotherapeutics has 453.0M shares outstanding, of which 394.3M are in the public float.

Biotechnology: ownership