Heron Therapeutics, Inc. (HRTX) Ownership

NASDAQ: HRTXTop holders, insider trades and short interest.

HRTX ownership summary

as of October 18, 2026
Institutions
70.3%
of shares outstanding
Insiders
0.98%
of shares outstanding
Shares outstanding
189.9M
Float
146.5M
shares available to trade
Short interest
30.88%
46.0M shares short
Days to cover
21.32
short interest up 6.1% vs prior month
  • Institutions 70.26%
  • Insiders 0.98%
  • Other investors 28.76%

HRTX top institutional holders

20 largest
Heron Therapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1Rubric Capital Management LP15.83%30.0M$10.8M—June 30, 2026
2Clearline Capital LP6.00%11.4M$4.1M−851,278 (−7.0%)June 30, 2026
3BlackRock Inc5.56%10.6M$3.8M+444,328 (+4.4%)June 30, 2026
4Velan Capital Investment Management LP4.61%8.8M$3.2M—June 30, 2026
5Vanguard Capital Management, LLC4.10%7.8M$2.8M−27,588 (−0.4%)June 30, 2026
6Tejara Capital Ltd3.43%6.5M$2.4M+174,040 (+2.7%)June 30, 2026
7TANG CAPITAL MANAGEMENT LLC3.29%6.2M$2.3M—June 30, 2026
8Geode Capital Management, LLC2.25%4.3M$1.5M+260,893 (+6.5%)June 30, 2026
9Millennium Management LLC2.14%4.1M$1.5M−3.6M (−46.7%)June 30, 2026
10JW Asset Management, LLC1.98%3.8M$1.4M—June 30, 2026
11State Street Corp1.70%3.2M$1.2M−615,115 (−16.0%)June 30, 2026
12UBS Group AG1.58%3.0M$1.1M+711,190 (+31.1%)June 30, 2026
13Pale Fire Capital SE1.32%2.5M$906,644−204,850 (−7.5%)June 30, 2026
14Marshall Wace Asset Management Ltd1.24%2.4M$849,864+2.4M (0.0%)June 30, 2026
15Richmond Brothers Inc0.94%1.8M$647,027+355,614 (+24.8%)June 30, 2026
16Vanguard Portfolio Management, LLC0.83%1.6M$570,564+271,198 (+20.7%)June 30, 2026
17AQR Capital Management LLC0.82%1.6M$560,942+912,270 (+142.2%)June 30, 2026
18Renaissance Technologies Corp0.79%1.5M$543,991−211,400 (−12.3%)June 30, 2026
19Vanguard Fiduciary Trust Co0.72%1.4M$492,808+212,405 (+18.4%)June 30, 2026
20The Goldman Sachs Group Inc0.70%1.3M$480,041+272,810 (+25.8%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 10 holders added 6.0M shares and 6 cut 5.5M.

HRTX top mutual fund and ETF holders

20 largest
Heron Therapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.88%5.5M$2.0M—August 31, 2026
2iShares Russell 2000 ETF1.95%3.7M$1.3M−42,688 (−1.1%)September 30, 2026
3Fidelity Small Cap Index0.86%1.6M$587,047−2,004 (−0.1%)July 31, 2026
4iShares Russell 2000 Growth ETF0.49%926K$334,418−1,173 (−0.1%)September 30, 2026
5Vanguard Russell 2000 ETF0.45%858K$309,846−56,916 (−6.2%)September 30, 2026
6Fidelity Extended Market Index0.33%632K$228,265−3,398 (−0.5%)August 31, 2026
7iShares Russell 2000 Value ETF0.27%513K$185,107+778 (+0.2%)September 30, 2026
8iShares Micro-Cap ETF0.25%470K$169,627−3,241 (−0.7%)September 30, 2026
9Schwab Small Cap Index0.22%414K$149,308—August 31, 2026
10Invesco NASDAQ Future Gen 200 ETF0.20%377K$136,072—September 30, 2026
11Jacob Small Cap Growth Investor0.19%357K$128,912—June 30, 2026
12Vanguard Health Care ETF0.17%328K$118,308+419 (+0.1%)September 30, 2026
13Fidelity Total Market Index0.17%318K$114,939—August 31, 2026
14Fidelity Series Total Market Index0.14%273K$98,621—August 31, 2026
15iShares Russell 2000 Small-Cap Idx Instl0.14%265K$95,677—August 31, 2026
16Advice Capital Globale0.13%250K$90,250—June 30, 2026
17Highland Global Allocation A0.12%233K$84,041—September 30, 2026
18Stt Strt SPDR® Russell2000 US SmCapETF0.12%227K$82,000−15,798 (−6.5%)September 30, 2026
19Jacob Discovery Fd Instl0.11%217K$78,323—June 30, 2026
20Invesco RAFI US 1500 Small-Mid ETF0.10%199K$71,908—September 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

HRTX insider transactions

latest 2
Heron Therapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2025-08-08Adam MorganBuy$1.501,766,546$2.6M
2025-08-08Rubric Capital Management LpBuy$1.502,387,225$3.6M

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

HRTX shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns HRTX

Institutional investors own 70.3% of Heron Therapeutics's shares and insiders 0.98%. The largest holder is Rubric Capital Management LP with 15.83% of the shares (30.0M), as of June 30, 2026. Among the top 20 institutions, 10 added shares and 6 reduced their stake in the latest filings. Short interest is 30.88% of the float, or 21.32 days of average trading volume. The share count rose 470.7% since 2014.

Related: HRTX analyst forecast, HRTX key metrics. See the HRTX stock overview for the latest quote and news.

HRTX ownership FAQ

Who owns the most Heron Therapeutics stock?

The largest shareholders of Heron Therapeutics are Rubric Capital Management LP (15.83%), Clearline Capital LP (6.00%), BlackRock Inc (5.56%), Velan Capital Investment Management LP (4.61%), Vanguard Capital Management, LLC (4.10%).

What percentage of Heron Therapeutics is owned by institutions?

Institutions hold 70.3% of Heron Therapeutics's shares outstanding; insiders hold 0.98%.

Which funds own Heron Therapeutics?

The largest fund holders of Heron Therapeutics are Vanguard MStar Total Stk Mkt Idx Invest (2.88%), iShares Russell 2000 ETF (1.95%), Fidelity Small Cap Index (0.86%), iShares Russell 2000 Growth ETF (0.49%), Vanguard Russell 2000 ETF (0.45%).

What is Heron Therapeutics's short interest?

46.0M shares of Heron Therapeutics were sold short, 30.88% of the float; at the average daily volume it would take 21.32 days to cover.

Are insiders buying or selling Heron Therapeutics?

Of the latest 2 reported insider transactions in Heron Therapeutics (since August 8, 2025), 2 were purchases and 0 were sales.

How many shares of Heron Therapeutics are outstanding?

Heron Therapeutics has 189.9M shares outstanding, of which 146.5M are in the public float.

Biotechnology: ownership