Heron Therapeutics, Inc. (HRTX) Key Metrics

NASDAQ: HRTXValuation, returns, debt and efficiency ratios over 10 years.

HRTX valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$68.5M
Enterprise value
$162.0M
P/E (TTM)
—
Forward P/E
46.9
PEG ratio
—
Price / sales
0.5
10-yr median 10.4
Price / book
9.4
10-yr median 8.1
EV / EBITDA
49.7
Dividend yield
—
Beta
1.62

HRTX key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

HRTX valuation Price multiples at each fiscal year-end price.

Price / sales−13.5%
1.4
2025 · hover or tap a bar for each year
2017: 31.82018: 24.5 (−22.9%)2019: 13.2 (−46.3%)2020: 21.7 (+64.6%)2021: 10.4 (−52.0%)2022: 2.5 (−75.7%)2023: 1.8 (−27.0%)2024: 1.6 (−12.5%)2025: 1.4 (−13.5%)
20162025
Price / book
15.1
2025 · hover or tap a bar for each year
2017: 7.52018: 5.1 (−31.2%)2019: 4.8 (−7.2%)2020: 8.1 (+70.7%)2021: 11.6 (+42.7%)2022: 20.1 (+73.2%)2025: 15.1
20162025
Free cash flow yield−2.5 pts
−12.9%
2025 · hover or tap a bar for each year
2017: −17.7%2018: −10.6% (+7.1 pts)2019: −6.9% (+3.7 pts)2020: −10.0% (−3.1 pts)2021: −23.0% (−13.0 pts)2022: −54.6% (−31.6 pts)2023: −25.7% (+28.9 pts)2024: −10.4% (+15.3 pts)2025: −12.9% (−2.5 pts)
20162025

HRTX valuation history

Fiscal year-endToday10-year median

HRTX returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

HRTX debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

HRTX price vs earnings per share

Share price at year-endEPS (right axis)

HRTX key metrics

2016–2025
Heron Therapeutics, Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$216.7M$233.2M$234.8M$272.5M$899.0M$1.92B$1.92B$1.90B$978.1M—
Enterprise value$310.7M$351.7M$334.0M$345.1M$901.0M$1.74B$1.55B$1.57B$834.4M—
Price / sales1.41.61.82.510.421.713.224.531.8—
Price / book15.1——20.111.68.14.85.17.5—
EV / sales2.02.42.63.210.419.610.620.327.1—
Earnings yield−9.3%−5.8%−47.1%−49.4%−24.2%−11.7%−10.7%−9.4%−20.2%—
Free cash flow yield−12.9%−10.4%−25.7%−54.6%−23.0%−10.0%−6.9%−10.6%−17.7%—
Dividend yield————————0.0%—
Shareholder yield (dividends + buybacks)————0.0%0.0%0.0%0.0%0.0%—
Share price at fiscal year-end$1.30$1.53$1.70$2.50$9.13$21.16$23.50$25.94$18.10$13.10
Per share
Revenue per share$0.93$0.95$0.92$0.99$0.88$0.98$1.78$1.06$0.57—
Earnings per share−$0.12−$0.09−$0.80−$1.23−$2.21−$2.47−$2.50−$2.44−$3.65—
Operating cash flow per share−$0.17−$0.15−$0.43−$1.35−$2.07−$2.04−$1.52−$2.62−$3.15—
Free cash flow per share−$0.17−$0.16−$0.44−$1.36−$2.10−$2.11−$1.61−$2.75−$3.20—
Cash per share$0.28$0.39$0.58$0.78$1.60$2.30$4.78$4.54$3.19—
Book value per share$0.09−$0.22−$0.25$0.12$0.79$2.61$4.94$5.06$2.43—
Tangible book value per share$0.09−$0.22−$0.25$0.12$0.79$2.61$4.94$5.06$2.43—
Dividends per share————————$0.00—
Capex per share$0.00$0.01$0.01$0.02$0.03$0.08$0.09$0.13$0.05—
Debt per share$0.84$1.17$1.30$1.44$1.62$0.27$0.24$0.06$0.53—
Shares outstanding166.7M152.4M138.1M109.0M98.5M90.8M81.8M73.2M54.0M—
Change in shares outstanding+9.4%+10.4%+26.7%+10.7%+8.5%+11.0%+11.7%+35.4%——
Returns & profitability
Return on equity (ROE)———−295.2%−138.6%−70.1%−52.9%−71.4%−359.4%—
Return on invested capital (ROIC)−2.1%−12.1%−115.4%−166.6%−260.5%−422.8%−443.8%−975.1%——
Return on assets (ROA)−8.3%−6.0%−46.7%−48.3%−66.0%−51.8%−42.0%−51.4%−130.9%−168.7%
Return on tangible assets−7.9%−5.8%−49.7%−53.6%−71.2%−63.5%−39.9%−38.7%−84.3%−256.6%
Free cash flow margin−18.0%−16.8%−47.5%−138.1%−239.0%−216.2%−90.2%−259.4%−561.8%—
Financial health
Total debt$140.6M$177.8M$179.6M$157.5M$159.5M$24.6M$19.8M$4.6M$28.7M$52.9M
Cash & short-term investments$46.6M$59.3M$80.4M$84.9M$157.6M$208.5M$391.0M$332.4M$172.4M$51.1M
Net debt$94.0M$118.5M$99.2M$72.6M$1.9M−$183.9M−$371.2M−$327.8M−$143.7M$1.8M
Debt / equity9.81——11.602.060.100.050.010.22—
Debt / assets0.550.760.810.630.520.070.040.010.120.78
Current ratio2.482.292.372.493.583.074.954.862.211.60
Quick ratio1.511.701.841.832.902.664.704.442.111.47
Interest coverage-0.3-1.9-28.6-70.6-90.4-120.0-143.1-68.8-49.4-64.2
Working capital$142.0M$117.6M$109.1M$123.1M$183.4M$211.7M$382.4M$355.2M$124.9M$23.4M
Invested capital$108.3M$84.8M$65.2M$86.2M$79.5M$52.6M$32.7M$42.4M−$12.6M−$19.5M
Tangible asset value$14.3M−$33.7M−$34.0M$13.6M$77.6M$236.5M$403.8M$370.2M$131.1M−$21.3M
Net current asset value−$3.5M−$57.8M−$67.7M−$31.9M$26.3M$197.1M$370.1M$355.2M$124.9M−$26.6M
Graham net-net per share−$0.49−$0.80−$0.80−$0.79−$0.20$1.58$3.97$4.21$1.96—
Capital allocation
Dividends paid————————$0$0
Share buybacks (net)————$0$0$0$0$0$0
Capex / revenue0.2%1.2%1.2%1.7%3.5%7.7%4.9%11.8%8.3%245.1%
Capex / depreciation0.140.680.530.631.002.393.506.061.672.85
Stock-based compensation / revenue6.7%9.0%25.9%39.9%54.3%56.7%35.2%43.1%99.3%2,029.4%
R&D / revenue8.0%11.6%30.8%99.8%151.5%196.9%114.7%180.7%450.4%8,062.9%
SG&A / revenue66.9%69.6%94.3%111.4%147.5%119.7%87.5%121.2%267.0%5,397.5%
Efficiency
Days sales outstanding198.5175.8161.2148.4163.5168.3130.7250.9260.0286.1
Days of inventory on hand644.0449.9271.0342.4358.0337.2189.6326.0614.527,844.3
Days payables outstanding91.473.220.724.817.918.659.0236.41,017.652,737.3
Cash conversion cycle (days)751.1552.5411.5466.0503.7486.9261.2340.5-143.1-24,606.9
Receivables turnover1.842.082.262.462.232.172.791.451.401.28
Payables turnover3.994.9817.6314.7120.4419.586.181.540.360.01
Inventory turnover0.570.811.351.071.021.081.931.120.590.01
Asset turnover0.630.630.540.390.260.200.300.220.200.01
Average receivables$84.2M$69.5M$56.1M$43.8M$38.7M$40.9M$52.3M$53.3M$21.9M$1.0M
Average payables$10.4M$7.8M$3.7M$3.7M$2.3M$1.8M$10.0M$17.8M$12.8M$5.1M
Average inventory$73.0M$47.6M$48.3M$51.5M$45.1M$33.4M$32.0M$24.6M$7.7M$2.7M
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%

Computed from HRTX's annual financial statements (latest annual report filed February 26, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

HRTX valuation and financial ratios

Heron Therapeutics earned a return on invested capital of −2.1% in fiscal 2025. It ended the year with $140.6 million of debt and $46.6 million in cash and short-term investments, net debt of $94.0 million.

See the HRTX income statement, the HRTX chart for price history, or the HRTX stock overview for the latest quote and news.

HRTX key metrics FAQ

What is Heron Therapeutics's ROIC?

Heron Therapeutics's return on invested capital was −2.1% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Heron Therapeutics have?

Heron Therapeutics had total debt of $140.6 million at the end of fiscal 2025, a debt-to-equity ratio of 9.81.

What is Heron Therapeutics's free cash flow yield?

Heron Therapeutics generated -$27.9 million of free cash flow in fiscal 2025, a free cash flow yield of −12.9% on its market value at year-end ($216.7 million).

What is Heron Therapeutics's current ratio?

Heron Therapeutics's current ratio was 2.48 at the end of fiscal 2025: current assets were 2.48 times current liabilities.

Biotechnology key metrics