Eton Pharmaceuticals, Inc. (ETON) Ownership

NASDAQ: ETONTop holders, insider trades and short interest.

ETON ownership summary

as of October 17, 2026
Institutions
71.3%
of shares outstanding
Insiders
4.89%
of shares outstanding
Shares outstanding
28.6M
Float
22.3M
shares available to trade
Short interest
8.87%
1.8M shares short
Days to cover
3.32
short interest up 18.9% vs prior month
  • Institutions 71.32%
  • Insiders 4.89%
  • Other investors 23.79%

ETON top institutional holders

20 largest
Eton Pharmaceuticals, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1Opaleye Management Inc10.01%2.9M$143.9M—June 30, 2026
2Nantahala Capital Management, LLC8.23%2.4M$118.3M+1.2M (+100.0%)June 30, 2026
3EcoR1 Capital, LLC7.60%2.2M$109.3M—June 30, 2026
4BlackRock Inc6.63%1.9M$95.4M+178,547 (+10.4%)June 30, 2026
5Vanguard Capital Management, LLC3.42%977K$49.1M−17,519 (−1.8%)June 30, 2026
6Morgan Stanley - Brokerage Accounts2.69%768K$38.6M+290,015 (+60.7%)June 30, 2026
7State Street Corp2.46%702K$35.3M+171,571 (+32.4%)June 30, 2026
8Geode Capital Management, LLC2.28%652K$32.8M+74,637 (+12.9%)June 30, 2026
9Oberweis Asset Management Inc1.75%502K$25.2M+62,300 (+14.2%)June 30, 2026
10National Philanthropic Trust1.72%492K$24.8M—June 30, 2026
11Westside Investment Management, Inc.1.51%431K$21.7M−36,755 (−7.9%)June 30, 2026
12Pillsbury Lake Capital LLC1.35%387K$19.5M+22,203 (+6.1%)June 30, 2026
13Nuveen, LLC1.31%376K$18.9M+317,757 (+548.3%)June 30, 2026
14BNP Paribas Arbitrage, SA1.13%322K$16.2M+20,358 (+6.7%)June 30, 2026
15Woodline Partners LP1.09%311K$15.6M+140,180 (+82.1%)June 30, 2026
16Thompson, Siegel & Walmsley LLC1.04%297K$15.0M−108,857 (−26.8%)June 30, 2026
17Northern Trust Corp0.90%256K$12.9M+18,017 (+7.6%)June 30, 2026
18Marshall Wace Asset Management Ltd0.87%249K$12.5M+166,461 (+201.2%)June 30, 2026
19Panoramic Capital, LLC0.73%208K$10.5M+23,192 (+12.5%)June 30, 2026
20Vanguard Portfolio Management, LLC0.68%195K$9.8M+42,843 (+28.2%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 14 holders added 2.7M shares and 3 cut 163K.

ETON top mutual fund and ETF holders

20 largest
Eton Pharmaceuticals, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.44%697K$35.1M—August 31, 2026
2iShares Russell 2000 ETF2.42%691K$34.8M−7,936 (−1.1%)September 30, 2026
3Oberweis Micro-Cap1.69%484K$24.3M+63,000 (+15.0%)June 30, 2026
4Fidelity Small Cap Index1.02%292K$14.7M+2,883 (+1.0%)July 31, 2026
5Fidelity Small Cap Growth0.89%253K$12.7M+252,960 (0.0%)July 31, 2026
6iShares Russell 2000 Growth ETF0.87%250K$12.6M−316 (−0.1%)September 30, 2026
7Nuveen Quant Small Cap Equity R60.79%226K$11.4M−27,400 (−10.8%)August 31, 2026
8State Street® SPDR® S&P® PhrmctlsETF0.62%177K$8.9M−2,200 (−1.2%)September 30, 2026
9Vanguard Russell 2000 ETF0.54%153K$7.7M+3,713 (+2.5%)August 31, 2026
10Schwab US Small-Cap ETF™0.50%143K$7.2M+90 (+0.1%)September 30, 2026
11Fidelity Small Cap Growth K60.46%132K$6.6M+131,980 (0.0%)July 31, 2026
12Fidelity Extended Market Index0.40%114K$5.7M−2,181 (−1.9%)August 31, 2026
13Rockefeller US Sm Cp Eq Impr F USDAccUnh0.39%113K$5.7M+15,956 (+16.5%)September 30, 2026
14Wasatch Micro Cap0.32%92K$4.6M+91,924 (0.0%)June 30, 2026
15iShares Micro-Cap ETF0.29%84K$4.2M−581 (−0.7%)September 30, 2026
16Fidelity® SAI Small-Mid Cap Momt Idx0.25%73K$3.7M+2,101 (+3.0%)August 31, 2026
17Schwab Small Cap Index0.23%65K$3.3M+620 (+1.0%)August 31, 2026
18Principal US Small Cap ETF0.21%61K$3.1M+30 (+0.0%)September 30, 2026
19Stt Strt SPDR® Russell2000 US SmCapETF0.19%54K$2.7M+2,560 (+5.0%)August 31, 2026
20iShares Russell 2000 Small-Cap Idx Instl0.17%50K$2.5M—August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

ETON insider transactions

latest 5
Eton Pharmaceuticals, Inc. insider transactions
DateNameTransactionPriceSharesValue
2025-08-20James R GruberSell$16.022,631$42,149
2025-08-19James R GruberSell$16.1639,082$631,565
2025-06-16David KrempaSell$14.7310,223$150,585
2025-06-13David KrempaSell$14.776,800$100,436
2025-06-12David KrempaSell$14.9216,977$253,297

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

ETON shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns ETON

Institutional investors own 71.3% of Eton Pharmaceuticals's shares and insiders 4.89%. The largest holder is Opaleye Management Inc with 10.01% of the shares (2.9M), as of June 30, 2026. Among the top 20 institutions, 14 added shares and 3 reduced their stake in the latest filings. Short interest is 8.87% of the float, or 3.32 days of average trading volume. The share count rose 651.6% since 2017.

Related: ETON analyst forecast, ETON key metrics. See the ETON stock overview for the latest quote and news.

ETON ownership FAQ

Who owns the most Eton Pharmaceuticals stock?

The largest shareholders of Eton Pharmaceuticals are Opaleye Management Inc (10.01%), Nantahala Capital Management, LLC (8.23%), EcoR1 Capital, LLC (7.60%), BlackRock Inc (6.63%), Vanguard Capital Management, LLC (3.42%).

What percentage of Eton Pharmaceuticals is owned by institutions?

Institutions hold 71.3% of Eton Pharmaceuticals's shares outstanding; insiders hold 4.89%.

Which funds own Eton Pharmaceuticals?

The largest fund holders of Eton Pharmaceuticals are Vanguard MStar Total Stk Mkt Idx Invest (2.44%), iShares Russell 2000 ETF (2.42%), Oberweis Micro-Cap (1.69%), Fidelity Small Cap Index (1.02%), Fidelity Small Cap Growth (0.89%).

What is Eton Pharmaceuticals's short interest?

1.8M shares of Eton Pharmaceuticals were sold short, 8.87% of the float; at the average daily volume it would take 3.32 days to cover.

Are insiders buying or selling Eton Pharmaceuticals?

Of the latest 5 reported insider transactions in Eton Pharmaceuticals (since June 12, 2025), 0 were purchases and 5 were sales.

How many shares of Eton Pharmaceuticals are outstanding?

Eton Pharmaceuticals has 28.6M shares outstanding, of which 22.3M are in the public float.

Drug Manufacturers - Specialty & Generic: ownership