C4 Therapeutics, Inc. (CCCC) Ownership

NASDAQ: CCCCTop holders, insider trades and short interest.

CCCC ownership summary

as of October 17, 2026
Institutions
104.2%
of shares outstanding
Insiders
0.84%
of shares outstanding
Shares outstanding
123.0M
Float
94.5M
shares available to trade
Short interest
33.03%
40.4M shares short
Days to cover
19.61
short interest up 0.5% vs prior month
  • Institutions 104.18%
  • Insiders 0.84%

CCCC top institutional holders

20 largest
C4 Therapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1Morgan Stanley - Brokerage Accounts7.21%8.9M$24.5M−205,062 (−2.3%)June 30, 2026
2RA Capital Management, LLC6.50%8.0M$22.1M—June 30, 2026
3BlackRock Inc6.42%7.9M$21.8M+5.8M (+285.5%)June 30, 2026
4Lynx1 Capital Management, LP5.96%7.3M$20.3M+327,789 (+4.7%)June 30, 2026
5Squadron Capital Management LLC5.85%7.2M$19.9M+5.0M (+220.0%)June 30, 2026
6Bain Capital Life Sciences Investors, LLC5.83%7.2M$19.8M—June 30, 2026
7JPMorgan Chase & Co3.86%4.7M$13.1M+1.5M (+47.3%)June 30, 2026
8Vanguard Capital Management, LLC3.59%4.4M$12.2M+555,879 (+14.4%)June 30, 2026
9Citadel Advisors Llc3.40%4.2M$11.6M+1.7M (+66.8%)June 30, 2026
10The Goldman Sachs Group Inc2.87%3.5M$9.8M+1.1M (+47.9%)June 30, 2026
11Wasatch Advisors LP2.86%3.5M$9.7M+560,883 (+18.9%)June 30, 2026
12Two Sigma Investments LLC2.82%3.5M$9.6M+434,073 (+14.3%)June 30, 2026
13Soleus Capital Management, L.P.2.75%3.4M$9.3M−425,961 (−11.2%)June 30, 2026
14SILVERARC CAPITAL MANAGEMENT, LLC2.46%3.0M$8.4M+1.1M (+58.6%)June 30, 2026
15Bank of America Corp2.16%2.7M$7.3M+297,118 (+12.6%)June 30, 2026
16Geode Capital Management, LLC2.05%2.5M$7.0M+1.6M (+165.2%)June 30, 2026
17Ikarian Capital, LLC1.98%2.4M$6.7M+2.4M (0.0%)June 30, 2026
18State Street Corp1.72%2.1M$5.8M+1.7M (+452.4%)June 30, 2026
19Acadian Asset Management LLC1.47%1.8M$5.0M−84,715 (−4.5%)June 30, 2026
20Candriam Luxembourg S.C.A.1.46%1.8M$5.0M+1.8M (0.0%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 15 holders added 26.0M shares and 3 cut 716K.

CCCC top mutual fund and ETF holders

20 largest
C4 Therapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.65%3.3M$9.0M—August 31, 2026
2iShares Russell 2000 ETF2.18%2.7M$7.4M−30,848 (−1.1%)September 30, 2026
3Wasatch Ultra Growth2.04%2.5M$6.9M−145,545 (−5.5%)June 30, 2026
4Fidelity Small Cap Index0.90%1.1M$3.1M+10,023 (+0.9%)July 31, 2026
5Fidelity Enhanced Small Cap Core ETF0.85%1.0M$2.9M+2,199 (+0.2%)September 30, 2026
6iShares Russell 2000 Value ETF0.76%936K$2.6M+1,420 (+0.2%)September 30, 2026
7iShares Biotechnology ETF0.71%876K$2.4M−6,640 (−0.8%)September 30, 2026
8Wasatch Micro Cap0.62%762K$2.1M+761,872 (0.0%)June 30, 2026
9JNL Multi-Manager Small Cap Value I0.52%634K$1.8M+162,157 (+34.4%)June 30, 2026
10Vanguard Russell 2000 ETF0.47%584K$1.6M+14,118 (+2.5%)August 31, 2026
11Schwab US Small-Cap ETF™0.45%551K$1.5M+369 (+0.1%)September 30, 2026
12Fidelity Extended Market Index0.37%460K$1.3M+13,978 (+3.1%)August 31, 2026
13iShares Micro-Cap ETF0.26%320K$883,650−2,204 (−0.7%)September 30, 2026
14Northern Small Cap Value0.25%307K$849,060+307,074 (0.0%)June 30, 2026
15Dimensional US Small Cap ETF0.22%271K$750,214—September 30, 2026
16Schwab Small Cap Index0.20%246K$681,288—August 31, 2026
17GuideStone Funds Small Cap Equity Instl0.19%235K$650,881+235,400 (0.0%)September 30, 2026
18CREF Total Global Stock Account R30.19%229K$632,411—July 31, 2026
19Invesco RAFI US 1500 Small-Mid ETF0.18%222K$614,046—September 30, 2026
20DFA US Micro Cap I0.17%209K$577,020+5,696 (+2.8%)August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

CCCC insider transactions

latest 1
C4 Therapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-01-16Leonard ReynoSell$2.2210,000$22,200

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

CCCC shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns CCCC

Institutional investors own 104.2% of C4 Therapeutics's shares and insiders 0.84%. The largest holder is Morgan Stanley - Brokerage Accounts with 7.21% of the shares (8.9M), as of June 30, 2026. Among the top 20 institutions, 15 added shares and 3 reduced their stake in the latest filings. Short interest is 33.03% of the float, or 19.61 days of average trading volume. The share count rose 577.7% since 2019.

Related: CCCC analyst forecast, CCCC key metrics. See the CCCC stock overview for the latest quote and news.

CCCC ownership FAQ

Who owns the most C4 Therapeutics stock?

The largest shareholders of C4 Therapeutics are Morgan Stanley - Brokerage Accounts (7.21%), RA Capital Management, LLC (6.50%), BlackRock Inc (6.42%), Lynx1 Capital Management, LP (5.96%), Squadron Capital Management LLC (5.85%).

What percentage of C4 Therapeutics is owned by institutions?

Institutions hold 104.2% of C4 Therapeutics's shares outstanding; insiders hold 0.84%.

Which funds own C4 Therapeutics?

The largest fund holders of C4 Therapeutics are Vanguard MStar Total Stk Mkt Idx Invest (2.65%), iShares Russell 2000 ETF (2.18%), Wasatch Ultra Growth (2.04%), Fidelity Small Cap Index (0.90%), Fidelity Enhanced Small Cap Core ETF (0.85%).

What is C4 Therapeutics's short interest?

40.4M shares of C4 Therapeutics were sold short, 33.03% of the float; at the average daily volume it would take 19.61 days to cover.

Are insiders buying or selling C4 Therapeutics?

Of the latest 1 reported insider transactions in C4 Therapeutics (since January 16, 2026), 0 were purchases and 1 were sales.

How many shares of C4 Therapeutics are outstanding?

C4 Therapeutics has 123.0M shares outstanding, of which 94.5M are in the public float.

Biotechnology: ownership