C4 Therapeutics, Inc. (CCCC) Cash Flow Statement

NASDAQ: CCCCOperating cash, capex, free cash flow and buybacks.

Where CCCC’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$98.7M
Capital expenditures
$607,000
1.7% of revenue
Free cash flow
−$99.3M
−276.2% margin
Returned to shareholders
$193,000
Change in cash
$19.1M
cash at year-end $78.0M
Shares issued: $126.2MShares issued$126.2MCash used in operations: $98.7MCash used in operations$98.7M · 78%Investments (net): $8.0MInvestments (net)$8.0M · 6%Added to cash: $19.1MAdded to cash$19.1M · 15%Capital expenditures: $607,000Capital expenditures$607,000 · 0%$126.4M
Cash from operations
−$98.7M
Capital expenditures
−$607,000
Investments (net)
−$8.0M
Shares issued
+$126.2M
Change in cash
$19.1M

Drawn to scale: where the cash came from and how it was used. Hover for values.

CCCC operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

CCCC cash flow trends, 2018–2025

C4 Therapeutics, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$17.0M2018−$98.7M2025—
Capital expenditures$2.7M2018$607,0002025−19.2%/yr
Free cash flow−$19.7M2018−$99.3M2025—
Free cash flow margin−101.6%2018−276.2%2025−174.7 pts
Stock-based compensation$582,0002018$19.1M2025+64.7%/yr
Share buybacks (net)$63,0002018$193,0002025+17.3%/yr
Capex / revenue13.9%20181.7%2025−12.2 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

CCCC cash flow by activity

OperatingInvestingFinancingChange in cash

CCCC net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

CCCC cash flow statement

C4 Therapeutics, Inc. annual cash flow statement
20252024202320222021202020192018
Operating activities
Net income−$105.0M−$105.3M−$132.5M−$128.2M−$83.9M−$66.3M−$34.1M−$15.7M
Depreciation & amortization$2.0M$1.8M$1.9M$1.7M$1.5M$1.6M$1.6M$1.3M
Stock-based compensation$19.1M$29.7M$27.2M$30.0M$21.5M$3.4M$1.6M$582,000
Change in working capital−$29.3M$7.6M−$6.9M−$16.8M−$30.1M−$13.2M$85.0M−$5.6M
Other non-cash items$14.5M$1.0M$3.5M$7.3M$4.0M$7.2M$1.5M$2.4M
Cash from operating activities−$98.7M−$65.2M−$106.8M−$105.9M−$87.0M−$67.2M$55.6M−$17.0M
Investing activities
Capital expenditures−$607,000−$180,000−$1.7M−$5.5M−$1.3M−$650,000−$1.3M−$2.7M
Investments (net)−$8.0M−$51.3M$135.7M$58.4M−$188.1M−$190.5M−$1.6M$36.9M
Acquisitions & other investing$0$180,000$24.4M$5.5M$0$650,000$1.3M$2.7M
Cash from investing activities−$8.6M−$51.3M$158.3M$58.4M−$189.3M−$190.5M−$1.6M$36.9M
Financing activities
Dividends paid—————−$12.0M——
Share repurchases & issuance (net)−$193,000−$194,000−$110,000$777,000$2.0M−$194,000−$30,000−$63,000
Net borrowing (repayment)—$0−$12.5M$0$0$12.5M$12.5M$12.5M
Shares issued$126.2M$44.4M$57.7M$0$169.5M$340.6M$274,000$2.0M
Other financing$381,000$1.2M$426,000$370,000−$109,000$8.0M−$12.5M−$12.5M
Cash from financing activities$126.4M$45.3M$45.5M$1.1M$171.4M$348.9M$244,000$2.0M
Summary
Net change in cash$19.1M−$71.1M$97.0M−$46.4M−$104.9M$91.2M$54.2M$21.9M
Cash at end of period$78.0M$58.9M$130.0M$33.0M$79.4M$184.3M$93.1M$38.9M
Free cash flow−$99.3M−$65.3M−$108.5M−$111.4M−$88.2M−$67.9M$54.3M−$19.7M
Free cash flow margin−276.2%−183.6%−523.0%−358.4%−192.7%−204.5%253.8%−101.6%
Capex / revenue1.7%0.5%8.2%17.7%2.8%2.0%6.3%13.9%

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

CCCC cash generation

In fiscal 2025 (ended December 31, 2025), C4 Therapeutics generated -$98.7 million of cash from operations and spent $0.6 million on capital expenditures, leaving free cash flow of -$99.3 million, −276.2% of revenue. It returned $0.2 million to shareholders through dividends ($0) and net share buybacks ($0.2 million). Cash and equivalents rose by $19.1 million over the year.

Related: CCCC income statement, CCCC balance sheet. See the CCCC stock overview for the latest quote and news.

CCCC cash flow FAQ

What is C4 Therapeutics's free cash flow?

C4 Therapeutics's free cash flow was -$99.3 million in fiscal 2025: -$98.7 million of operating cash flow minus $0.6 million of capital expenditures It was -$65.3 million a year earlier..

How much cash does C4 Therapeutics generate from operations?

C4 Therapeutics generated -$98.7 million of cash from operating activities in fiscal 2025.

How much does C4 Therapeutics spend on capital expenditures?

C4 Therapeutics spent $0.6 million on capital expenditures in fiscal 2025, 1.7% of revenue, compared with $0.2 million the year before.

How much stock does C4 Therapeutics buy back?

C4 Therapeutics spent $0.2 million on net share repurchases in fiscal 2025.

Biotechnology: cash flow