Crescent Biopharma, Inc. (CBIO) Ownership

NASDAQ: CBIOTop holders, insider trades and short interest.

CBIO ownership summary

as of October 18, 2026
Institutions
82.8%
of shares outstanding
Insiders
0.27%
of shares outstanding
Shares outstanding
37.1M
Float
27.0M
shares available to trade
Short interest
22.07%
4.8M shares short
Days to cover
8.78
short interest up 40.2% vs prior month
  • Institutions 82.82%
  • Insiders 0.27%
  • Other investors 16.92%

CBIO top institutional holders

20 largest
Crescent Biopharma, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1FMR Inc11.13%4.1M$48.9M—June 30, 2026
2Bvf Inc7.40%2.7M$32.5M—June 30, 2026
3Fairmount Funds Management LLC7.40%2.7M$32.5M—June 30, 2026
4VR Adviser, LLC5.74%2.1M$25.3M—June 30, 2026
5Logos Global Management LP5.11%1.9M$22.5M+1.4M (+293.8%)June 30, 2026
6FCPM III SERVICES BV4.52%1.7M$19.9M—June 30, 2026
7Balyasny Asset Management LLC4.48%1.7M$19.7M+152,884 (+10.1%)June 30, 2026
8Vestal Point Capital LP4.39%1.6M$19.3M+130,000 (+8.7%)June 30, 2026
9Opaleye Management Inc3.55%1.3M$15.6M+6,736 (+0.5%)June 30, 2026
10BlackRock Inc3.42%1.3M$15.1M+1.2M (+999.0%)June 30, 2026
11TANG CAPITAL MANAGEMENT LLC3.12%1.2M$13.7M—June 30, 2026
12Vanguard Capital Management, LLC2.07%768K$9.1M−33,640 (−4.2%)June 30, 2026
13Boxer Capital Management, LLC1.22%454K$5.4M—June 30, 2026
14Millennium Management LLC1.09%404K$4.8M+80,306 (+24.8%)June 30, 2026
15Geode Capital Management, LLC1.04%385K$4.6M+280,355 (+269.0%)June 30, 2026
16Jennison Associates LLC1.02%379K$4.5M+225,533 (+147.4%)June 30, 2026
17NEXTBio Capital Management LP1.00%373K$4.4M—June 30, 2026
18RTW INVESTMENTS, LLC1.00%373K$4.4M—June 30, 2026
19Remedium Capital Partners, LLC0.97%361K$4.3M+361,250 (0.0%)June 30, 2026
20State Street Corp0.85%316K$3.7M+276,520 (+707.8%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 10 holders added 4.1M shares and 1 cut 34K.

CBIO top mutual fund and ETF holders

20 largest
Crescent Biopharma, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Fidelity Small Cap Growth2.56%951K$11.3M+432,286 (+83.4%)July 31, 2026
2Fidelity Growth Company Fund2.53%939K$11.1M+646,839 (+221.3%)August 31, 2026
3Vanguard MStar Total Stk Mkt Idx Invest2.44%907K$10.7M—August 31, 2026
4iShares Russell 2000 ETF1.99%738K$8.7M−8,512 (−1.1%)September 30, 2026
5Fidelity Small Cap Growth K61.24%461K$5.5M+221,488 (+92.4%)July 31, 2026
6Fidelity Advisor Biotechnology I1.23%457K$5.4M+100,500 (+28.2%)August 31, 2026
7Fidelity Select Biotechnology0.91%340K$4.0M+149,142 (+78.3%)August 31, 2026
8State Street® SPDR® S&P® Biotech ETF0.90%335K$4.0M−6,400 (−1.9%)September 30, 2026
9PGIM Jennison Health Sciences Z0.84%311K$3.7M—August 31, 2026
10Fidelity Select Health Care0.83%308K$3.6M+6,400 (+2.1%)August 31, 2026
11Fidelity Growth Company K60.78%290K$3.4M+186,117 (+179.8%)August 31, 2026
12iShares Russell 2000 Growth ETF0.73%271K$3.2M−343 (−0.1%)September 30, 2026
13Fidelity Small Cap Index0.64%236K$2.8M+2,268 (+1.0%)July 31, 2026
14Fidelity Series Growth Company0.63%234K$2.8M+165,200 (+238.7%)August 31, 2026
15Fidelity Advisor Health Care I0.41%153K$1.8M+3,117 (+2.1%)August 31, 2026
16Vanguard Russell 2000 ETF0.33%124K$1.5M+2,520 (+2.1%)August 31, 2026
17iShares Micro-Cap ETF0.25%92K$1.1M−632 (−0.7%)September 30, 2026
18Fidelity Small Cap Stock0.18%66K$777,888+65,700 (0.0%)July 31, 2026
19Vanguard Health Care ETF0.17%63K$740,142+276 (+0.4%)August 31, 2026
20Fidelity VIP Health Care Initial0.15%58K$681,120+1,200 (+2.1%)August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

CBIO insider transactions

latest 1
Crescent Biopharma, Inc. insider transactions
DateNameTransactionPriceSharesValue
2025-12-04Fairmount Funds Management LlcBuy$13.411,360,000$18.2M

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

CBIO shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns CBIO

Institutional investors own 82.8% of Crescent Biopharma's shares and insiders 0.27%. The largest holder is FMR Inc with 11.13% of the shares (4.1M), as of June 30, 2026. Among the top 20 institutions, 10 added shares and 1 reduced their stake in the latest filings. Short interest is 22.07% of the float, or 8.78 days of average trading volume. The share count rose 10,572.3% since 2014.

Related: CBIO analyst forecast, CBIO key metrics. See the CBIO stock overview for the latest quote and news.

CBIO ownership FAQ

Who owns the most Crescent Biopharma stock?

The largest shareholders of Crescent Biopharma are FMR Inc (11.13%), Bvf Inc (7.40%), Fairmount Funds Management LLC (7.40%), VR Adviser, LLC (5.74%), Logos Global Management LP (5.11%).

What percentage of Crescent Biopharma is owned by institutions?

Institutions hold 82.8% of Crescent Biopharma's shares outstanding; insiders hold 0.27%.

Which funds own Crescent Biopharma?

The largest fund holders of Crescent Biopharma are Fidelity Small Cap Growth (2.56%), Fidelity Growth Company Fund (2.53%), Vanguard MStar Total Stk Mkt Idx Invest (2.44%), iShares Russell 2000 ETF (1.99%), Fidelity Small Cap Growth K6 (1.24%).

What is Crescent Biopharma's short interest?

4.8M shares of Crescent Biopharma were sold short, 22.07% of the float; at the average daily volume it would take 8.78 days to cover.

Are insiders buying or selling Crescent Biopharma?

Of the latest 1 reported insider transactions in Crescent Biopharma (since December 4, 2025), 1 were purchases and 0 were sales.

How many shares of Crescent Biopharma are outstanding?

Crescent Biopharma has 37.1M shares outstanding, of which 27.0M are in the public float.

Biotechnology: ownership