Bicycle Therapeutics plc (BCYC) Ownership

NASDAQ: BCYCTop holders, insider trades and short interest.

BCYC ownership summary

as of October 18, 2026
Institutions
71.9%
of shares outstanding
Insiders
4.41%
of shares outstanding
Shares outstanding
50.4M
Float
7.8M
shares available to trade
Short interest
8.46%
3.3M shares short
Days to cover
7.64
short interest down 0.9% vs prior month
  • Institutions 71.86%
  • Insiders 4.41%
  • Other investors 23.74%

BCYC top institutional holders

20 largest
Bicycle Therapeutics plc top institutional holders
#Holder% of sharesSharesValueChangeReported
1Baker Bros Advisors LP15.55%10.9M$37.7M—June 30, 2026
2FCPM III SERVICES BV4.96%3.5M$12.0M—June 30, 2026
3Armistice Capital, LLC4.85%3.4M$11.8M—June 30, 2026
4Long Focus Capital Management, LLC4.73%3.3M$11.5M—June 30, 2026
5Acadian Asset Management LLC2.81%2.0M$6.8M—June 30, 2026
6Renaissance Technologies Corp2.19%1.5M$5.3M+554,100 (+56.6%)June 30, 2026
7GSK PLC2.19%1.5M$5.3M—June 30, 2026
8T. Rowe Price Associates, Inc.1.29%902K$3.1M−126,093 (−12.3%)June 30, 2026
9Marshall Wace Asset Management Ltd1.14%798K$2.8M+420,605 (+111.5%)June 30, 2026
10Qube Research & Technologies1.11%776K$2.7M+466,950 (+151.3%)June 30, 2026
11Morgan Stanley - Brokerage Accounts0.95%667K$2.3M+48,942 (+7.9%)June 30, 2026
12Schroder Investment Management Group0.88%616K$2.1M—June 30, 2026
13Citadel Advisors Llc0.79%554K$1.9M+177,140 (+47.0%)June 30, 2026
14Millennium Management LLC0.79%554K$1.9M+269,981 (+95.1%)June 30, 2026
15Peapod Lane Capital LLC0.77%538K$1.9M+416,872 (+344.2%)June 30, 2026
16Diadema Partners LP0.66%463K$1.6M−13,700 (−2.9%)June 30, 2026
17Two Sigma Investments LLC0.62%435K$1.5M+269,777 (+163.7%)June 30, 2026
18Jane Street Group LLC0.56%392K$1.4M+174,048 (+79.8%)June 30, 2026
19FLAX POND CAPITAL, LLC0.54%376K$1.3M+200,086 (+113.6%)June 30, 2026
20Birchview Capital, LP0.45%314K$1.1M−149,983 (−32.4%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 10 holders added 3.0M shares and 3 cut 290K.

BCYC top mutual fund and ETF holders

20 largest
Bicycle Therapeutics plc top fund holders
#Holder% of sharesSharesValueChangeReported
1International Biotechnology Ord0.88%616K$2.1M—June 30, 2026
2iShares Biotechnology ETF0.42%292K$1.0M−2,208 (−0.8%)September 30, 2026
3Old Westbury Small & Mid Cap Strategies0.38%266K$920,267—July 31, 2026
4Virtus LifeSci Biotech Clinical Trls ETF0.11%78K$271,105—September 30, 2026
5ALPS Medical Breakthroughs ETF0.10%67K$230,093—September 30, 2026
6PPF Helix Biotechnology I USD0.08%58K$201,718—June 30, 2026
7TD Health Sciences - I0.07%46K$159,146—June 30, 2026
8iShares Nasdaq US Biotech ETF USD Acc0.05%38K$131,518+328 (+0.9%)September 30, 2026
9State Street® SPDR® S&P® Intl Sm Cp ETF0.05%37K$128,798—September 30, 2026
10Voya Multi-Manager International Sm Cp A0.04%30K$103,980—June 30, 2026
11Invesco NASDAQ Future Gen 200 ETF0.04%29K$100,420—September 30, 2026
12Acadian Eurp Eq C2-i-0.7500-EUR0.04%26K$89,856—June 30, 2026
13JHVIT Health Sciences I0.04%26K$88,583—August 31, 2026
14Acadian European SmCp Eq C2-i-0.7500-EUR0.03%24K$83,383—June 30, 2026
15ActivePassive International Equity ETF0.03%20K$70,719—September 30, 2026
16Portland Life Sciences Alt F0.02%15K$51,900—September 30, 2026
17ERSTE STOCK BIOTEC EUR R01 A0.02%14K$48,440—August 31, 2026
18The AtonRâ Fund Founder USD Acc0.02%12K$40,122−3,111 (−21.2%)June 30, 2026
19Horizon Kinetics Medical ETF0.02%11K$39,354—September 30, 2026
20Steward Values Enhanced International I0.02%11K$38,783—August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

BCYC insider transactions

latest 20
Bicycle Therapeutics plc insider transactions
DateNameTransactionPriceSharesValue
2026-04-06Kevin LeeSell$5.051,716$8,666
2026-04-06Travis Alvin ThompsonSell$5.05102$515
2026-04-06Jennifer Scott PerrySell$5.04370$1,865
2026-04-02Jennifer Scott PerrySell$4.911,038$5,097
2026-04-02Kevin LeeSell$4.915,967$29,298
2026-04-02Travis Alvin ThompsonSell$4.91799$3,923
2026-01-05Alethia YoungSell$6.494,334$28,128
2026-01-05Alistair MilnesSell$6.463,416$22,067
2026-01-05Kevin LeeSell$6.4610,989$70,989
2026-01-05Travis Alvin ThompsonSell$6.451,115$7,192
2026-01-02Alethia YoungSell$6.803,289$22,365
2026-01-02Alistair MilnesSell$6.803,244$22,059
2026-01-02Kevin LeeSell$6.8010,325$70,210
2026-01-02Travis Alvin ThompsonSell$6.801,317$8,956
2025-10-03Alistair MilnesSell$8.41978$8,225
2025-10-03Travis Alvin ThompsonSell$8.41103$866
2025-10-03Kevin LeeSell$8.413,231$27,173
2025-10-02Alethia YoungSell$8.51482$4,102
2025-10-02Alistair MilnesSell$8.401,147$9,635
2025-10-02Kevin LeeSell$8.402,263$19,009

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

BCYC shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns BCYC

Institutional investors own 71.9% of Bicycle Therapeutics's shares and insiders 4.41%. The largest holder is Baker Bros Advisors LP with 15.55% of the shares (10.9M), as of June 30, 2026. Among the top 20 institutions, 10 added shares and 3 reduced their stake in the latest filings. Short interest is 8.46% of the float, or 7.64 days of average trading volume. The share count rose 347.7% since 2017.

Related: BCYC analyst forecast, BCYC key metrics. See the BCYC stock overview for the latest quote and news.

BCYC ownership FAQ

Who owns the most Bicycle Therapeutics stock?

The largest shareholders of Bicycle Therapeutics are Baker Bros Advisors LP (15.55%), FCPM III SERVICES BV (4.96%), Armistice Capital, LLC (4.85%), Long Focus Capital Management, LLC (4.73%), Acadian Asset Management LLC (2.81%).

What percentage of Bicycle Therapeutics is owned by institutions?

Institutions hold 71.9% of Bicycle Therapeutics's shares outstanding; insiders hold 4.41%.

Which funds own Bicycle Therapeutics?

The largest fund holders of Bicycle Therapeutics are International Biotechnology Ord (0.88%), iShares Biotechnology ETF (0.42%), Old Westbury Small & Mid Cap Strategies (0.38%), Virtus LifeSci Biotech Clinical Trls ETF (0.11%), ALPS Medical Breakthroughs ETF (0.10%).

What is Bicycle Therapeutics's short interest?

3.3M shares of Bicycle Therapeutics were sold short, 8.46% of the float; at the average daily volume it would take 7.64 days to cover.

Are insiders buying or selling Bicycle Therapeutics?

Of the latest 20 reported insider transactions in Bicycle Therapeutics (since October 2, 2025), 0 were purchases and 20 were sales.

How many shares of Bicycle Therapeutics are outstanding?

Bicycle Therapeutics has 50.4M shares outstanding, of which 7.8M are in the public float.

Biotechnology: ownership