Bicycle Therapeutics plc (BCYC) Cash Flow Statement

NASDAQ: BCYCOperating cash, capex, free cash flow and buybacks.

Where BCYC’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$249.7M
Capital expenditures
$2.4M
3.2% of revenue
Free cash flow
−$252.6M
−348.0% margin
Returned to shareholders
—
Change in cash
−$251.4M
cash at year-end $628.7M
Drawn from cash: $251.4MDrawn from cash$251.4MCash used in operations: $249.7MCash used in operations$249.7M · 99%Capital expenditures: $2.4MCapital expenditures$2.4M · 1%$252.0M
Cash from operations
−$249.7M
Capital expenditures
−$2.4M
Change in cash
−$251.4M

Drawn to scale: where the cash came from and how it was used. Hover for values.

BCYC operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

BCYC cash flow trends, 2016–2025

Bicycle Therapeutics plc cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$11.3M2016−$249.7M2025—
Capital expenditures$243,3582016$2.4M2025+28.7%/yr
Free cash flow−$11.5M2016−$252.6M2025—
Free cash flow margin−122.7%2017−348.0%2025−225.3 pts
Stock-based compensation$123,0002016$39.5M2025+89.9%/yr
Dividends paid$02016$02018—
Share buybacks (net)$02016$02019—
Capex / revenue54.0%20173.2%2025−50.8 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

BCYC cash flow by activity

OperatingInvestingFinancingChange in cash

BCYC net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

BCYC cash flow statement

Bicycle Therapeutics plc annual cash flow statement
2025202420232022202120202019201820172016
Operating activities
Net income−$219.0M−$169.0M−$180.7M−$112.7M−$66.8M−$51.0M−$30.6M−$21.8M−$16.3M−$13.5M
Depreciation & amortization$6.4M$7.2M$6.5M$3.7M$1.4M$1.3M$960,000$712,000$332,000$269,289
Stock-based compensation$39.5M$38.1M$32.5M$26.8M$12.1M$6.5M$3.1M$1.0M$515,000$123,000
Change in working capital−$75.8M−$33.5M$76.7M$672,000$38.1M$25.4M−$7.4M−$6.6M$13.0M$1.9M
Other non-cash items−$850,000−$7.5M$4.3M−$4.5M$468,000$78,000$5.4M$665,000$975,000−$323
Cash from operating activities−$249.7M−$164.7M−$60.6M−$86.1M−$14.8M−$17.8M−$28.6M−$26.1M−$1.4M−$11.3M
Investing activities
Capital expenditures−$2.4M−$1.2M−$2.9M−$19.0M−$2.0M−$1.2M−$1.6M−$1.2M−$1.1M−$243,358
Investments (net)—−$1.2M−$4.3M−$19.0M−$2.0M−$1.2M−$1.6M−$1.2M−$1.1M$0
Acquisitions & other investing$5,492$1.2M$4.3M$19.0M$2.0M$1.2M$1.6M$1.2M$1.1M$0
Cash from investing activities−$2.4M−$1.2M−$2.9M−$19.0M−$2.0M−$1.2M−$1.6M−$1.2M−$1.1M−$243,358
Financing activities
Dividends paid———————$0$0$0
Share repurchases & issuance (net)——————$58.4M−$576,000$57.9M$16.8M
Net borrowing (repayment)−$168,000−$31.9M$0$0$15.0M$15.0M$15.0M$15.0M$15.0M$0
Shares issued$0$544.1M$255.0M$5.7M$298.5M$48.1M$58.3M$26.0M$0$0
Other financing$37,000$7.5M−$5.0M$989,000$7.2M−$301,000−$73.3M−$15.0M−$15.0M−$44,246
Cash from financing activities−$131,000$519.8M$250.0M$6.7M$320.7M$62.8M$58.4M$25.4M$57.9M$16.8M
Summary
Net change in cash−$251.4M$353.1M$187.8M−$99.5M$302.7M$43.9M$28.7M−$4.3M$58.3M$3.5M
Cash at end of period$628.7M$880.1M$527.0M$339.2M$438.7M$136.0M$92.1M$63.4M$67.7M$9.4M
Free cash flow−$252.6M−$166.0M−$63.6M−$105.1M−$16.8M−$19.0M−$30.2M−$27.3M−$2.5M−$11.5M
Free cash flow margin−348.0%−470.5%−235.6%−726.7%−143.8%−182.8%−218.6%−382.1%−122.7%—
Capex / revenue3.2%3.5%10.9%131.3%17.4%11.5%11.3%16.6%54.0%—

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

BCYC cash generation

In fiscal 2025 (ended December 31, 2025), Bicycle Therapeutics generated -$249.7 million of cash from operations and spent $2.4 million on capital expenditures, leaving free cash flow of -$252.6 million, −348.0% of revenue. Cash and equivalents fell by $251.4 million over the year.

Related: BCYC income statement, BCYC balance sheet. See the BCYC stock overview for the latest quote and news.

BCYC cash flow FAQ

What is Bicycle Therapeutics's free cash flow?

Bicycle Therapeutics's free cash flow was -$252.6 million in fiscal 2025: -$249.7 million of operating cash flow minus $2.4 million of capital expenditures It was -$166.0 million a year earlier..

How much cash does Bicycle Therapeutics generate from operations?

Bicycle Therapeutics generated -$249.7 million of cash from operating activities in fiscal 2025.

How much does Bicycle Therapeutics spend on capital expenditures?

Bicycle Therapeutics spent $2.4 million on capital expenditures in fiscal 2025, 3.2% of revenue, compared with $1.2 million the year before.

Biotechnology: cash flow