Aytu BioPharma, Inc. (AYTU) Ownership

NASDAQ: AYTUTop holders, insider trades and short interest.

AYTU ownership summary

as of October 17, 2026
Institutions
35.5%
of shares outstanding
Insiders
8.16%
of shares outstanding
Shares outstanding
10.9M
Float
7.7M
shares available to trade
Short interest
3.69%
345K shares short
Days to cover
7.10
short interest up 10.8% vs prior month
  • Institutions 35.51%
  • Insiders 8.16%
  • Other investors 56.32%

AYTU top institutional holders

20 largest
Aytu BioPharma, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1Nantahala Capital Management, LLC20.00%2.2M$4.4M+1.1M (+100.0%)June 30, 2026
2Stonepine Capital Management Llc8.40%913K$1.9M+120,632 (+15.2%)June 30, 2026
3Awm Investment Company Inc5.70%620K$1.3M—June 30, 2026
4Vanguard Capital Management, LLC2.40%261K$532,738—June 30, 2026
5CROWN ADVISORS MANAGEMENT, INC.1.84%200K$408,000+55,000 (+37.9%)June 30, 2026
6Diadema Partners LP1.37%149K$303,034−204,531 (−57.9%)June 30, 2026
7Two Sigma Investments LLC0.97%105K$214,865−16,647 (−13.6%)June 30, 2026
8Renaissance Technologies Corp0.96%105K$213,839+11,100 (+11.8%)June 30, 2026
9Geode Capital Management, LLC0.86%94K$191,040+1,011 (+1.1%)June 30, 2026
10Arete Wealth Advisors, LLC0.46%50K$101,080+49,549 (0.0%)March 31, 2026
11Citadel Advisors Llc0.45%49K$100,805+12,573 (+34.1%)June 30, 2026
12Vanguard Fiduciary Trust Co0.43%47K$95,978—June 30, 2026
13Dimensional Fund Advisors, Inc.0.42%45K$92,465+1,741 (+4.0%)June 30, 2026
14Persistent Asset Partners Limited0.35%38K$77,487−54,913 (−59.1%)June 30, 2026
15Northern Trust Corp0.26%28K$56,967+8,756 (+45.7%)June 30, 2026
16Bellevue Asset Management, LLC0.23%25K$51,027—June 30, 2026
17BlackRock Inc0.21%23K$46,498—June 30, 2026
18XTX Topco Ltd0.20%21K$43,689−166 (−0.8%)June 30, 2026
19Acadian Asset Management LLC0.09%10K$20,883—June 30, 2026
20Daytona Street Capital LLC0.09%10K$20,400—June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 9 holders added 1.3M shares and 4 cut 276K.

AYTU top mutual fund and ETF holders

18 largest
Aytu BioPharma, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest1.56%169K$344,760—August 31, 2026
2Fidelity Extended Market Index0.45%49K$99,244−261 (−0.5%)August 31, 2026
3Perritt MicroCap Opportunities Investor0.18%20K$40,800+20,000 (0.0%)December 31, 2025
4Fidelity Series Total Market Index0.13%14K$28,756—August 31, 2026
5Fidelity Total Market Index0.09%9,757$19,904—August 31, 2026
6DFA US Core Equity Class F0.05%5,523$11,267—July 31, 2026
7DFA US Vector Equity I0.05%5,481$11,181—August 31, 2026
8DFA US Vector Equity Class F0.05%5,319$10,851—July 31, 2026
9Dimensional US Sustainability Core 1 ETF0.04%4,805$9,802—September 30, 2026
10DFA US Sustainability Core 10.04%4,640$9,466—August 31, 2026
11Dimensional US Small Cap ETF0.04%4,402$8,980—September 30, 2026
12Dimensional US Core Equity 2 ETF0.04%4,122$8,409—September 30, 2026
13DFA US Core Equity 1 I0.04%4,100$8,364—August 31, 2026
14Dimensional US Core Equity 1 ETF0.02%2,147$4,380—September 24, 2026
15DFA US Social Core Equity 2 Portfolio0.02%1,741$3,552—August 31, 2026
16DFA US Core Equity 2 I0.02%1,710$3,488—August 31, 2026
17Bridgeway Omni Small-Cap Value N0.01%1,500$3,060—June 30, 2026
18Dimensional US Core Equity USD Acc0.01%1,336$2,725—August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

AYTU insider transactions

latest 3
Aytu BioPharma, Inc. insider transactions
DateNameTransactionPriceSharesValue
2025-02-28Joshua R DisbrowBuy$1.3015,000$19,500
2023-06-16Greg PyszczymukaBuy$1.8712,000$22,440
2023-06-14Joshua R DisbrowBuy$1.8614,000$26,040

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

AYTU shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns AYTU

Institutional investors own 35.5% of Aytu BioPharma's shares and insiders 8.16%. The largest holder is Nantahala Capital Management, LLC with 20.00% of the shares (2.2M), as of June 30, 2026. Among the top 20 institutions, 9 added shares and 4 reduced their stake in the latest filings. Short interest is 3.69% of the float, or 7.10 days of average trading volume. The share count rose 10,036,300.0% since 2016.

Related: AYTU analyst forecast, AYTU key metrics. See the AYTU stock overview for the latest quote and news.

AYTU ownership FAQ

Who owns the most Aytu BioPharma stock?

The largest shareholders of Aytu BioPharma are Nantahala Capital Management, LLC (20.00%), Stonepine Capital Management Llc (8.40%), Awm Investment Company Inc (5.70%), Vanguard Capital Management, LLC (2.40%), CROWN ADVISORS MANAGEMENT, INC. (1.84%).

What percentage of Aytu BioPharma is owned by institutions?

Institutions hold 35.5% of Aytu BioPharma's shares outstanding; insiders hold 8.16%.

Which funds own Aytu BioPharma?

The largest fund holders of Aytu BioPharma are Vanguard MStar Total Stk Mkt Idx Invest (1.56%), Fidelity Extended Market Index (0.45%), Perritt MicroCap Opportunities Investor (0.18%), Fidelity Series Total Market Index (0.13%), Fidelity Total Market Index (0.09%).

What is Aytu BioPharma's short interest?

345K shares of Aytu BioPharma were sold short, 3.69% of the float; at the average daily volume it would take 7.10 days to cover.

Are insiders buying or selling Aytu BioPharma?

Of the latest 3 reported insider transactions in Aytu BioPharma (since June 14, 2023), 3 were purchases and 0 were sales.

How many shares of Aytu BioPharma are outstanding?

Aytu BioPharma has 10.9M shares outstanding, of which 7.7M are in the public float.

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