Annovis Bio, Inc. (ANVS) Ownership

NYSE: ANVSTop holders, insider trades and short interest.

ANVS ownership summary

as of October 18, 2026
Institutions
22.2%
of shares outstanding
Insiders
11.79%
of shares outstanding
Shares outstanding
42.7M
Float
37.9M
shares available to trade
Short interest
15.66%
5.9M shares short
Days to cover
4.29
short interest up 18.2% vs prior month
  • Institutions 22.21%
  • Insiders 11.79%
  • Other investors 66.00%

ANVS top institutional holders

20 largest
Annovis Bio, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1Empery Asset Management, LP5.63%2.4M$2.4M+2.4M (0.0%)June 30, 2026
2Marshall Wace Asset Management Ltd4.32%1.8M$1.8M+654,840 (+55.1%)June 30, 2026
3Vanguard Capital Management, LLC3.86%1.6M$1.6M+774,941 (+88.8%)June 30, 2026
4Tudor Investment Corp Et AL3.18%1.4M$1.3M+1.4M (0.0%)June 30, 2026
5Renaissance Technologies Corp2.35%1.0M$992,178+654,600 (+188.3%)June 30, 2026
6Two Sigma Investments LLC1.36%580K$573,775−48,088 (−7.7%)June 30, 2026
7Geode Capital Management, LLC0.67%284K$280,979+36,304 (+14.7%)June 30, 2026
8BlackRock Inc0.59%250K$247,357+110,323 (+79.1%)June 30, 2026
9Citadel Advisors Llc0.57%244K$241,245+243,682 (0.0%)June 30, 2026
10Vanguard Fiduciary Trust Co0.42%178K$175,755+45,488 (+34.4%)June 30, 2026
11Susquehanna International Group, LLP0.34%147K$145,336−71,532 (−32.8%)June 30, 2026
12Quadrature Capital Limited0.21%91K$89,975+90,884 (0.0%)June 30, 2026
13State Street Corp0.18%78K$76,958—June 30, 2026
14Northern Trust Corp0.16%68K$67,389−73,660 (−52.0%)June 30, 2026
15First National Trust Co0.14%60K$59,400+20,000 (+50.0%)June 30, 2026
16Sherry Group Inc0.13%57K$56,697—September 30, 2026
17GSA Capital Partners LLP0.12%50K$49,405+4,481 (+9.9%)June 30, 2026
18Greenwich Wealth Management LLC0.11%48K$47,916+1,400 (+3.0%)June 30, 2026
19Headlands Technologies LLC0.11%48K$47,590+48,071 (0.0%)June 30, 2026
20Wescott Financial Advisory Group, LLC0.10%42K$41,191—June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 14 holders added 6.4M shares and 3 cut 193K.

ANVS top mutual fund and ETF holders

10 largest
Annovis Bio, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.86%1.2M$1.2M—August 31, 2026
2Fidelity Extended Market Index0.36%152K$150,794−819 (−0.5%)August 31, 2026
3iShares Micro-Cap ETF0.23%99K$97,586−680 (−0.7%)September 30, 2026
4Fidelity Series Total Market Index0.11%46K$45,235—August 31, 2026
5Fidelity Total Market Index0.10%42K$41,601+7,562 (+21.9%)August 31, 2026
6EA Bridgeway Ultra-Small Company Mkt ETF0.08%33K$32,800—September 30, 2026
7Vanguard Balanced Index Inv0.05%21K$20,784—August 31, 2026
8Vanguard U.S. Eq Idx £ Acc0.03%11K$11,078—August 31, 2026
91290 VT Micro Cap K0.02%6,991$6,921—August 31, 2026
10JHVIT Total Stock Market Index I<0.01%959$949+402 (+72.2%)August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

ANVS insider transactions

latest 7
Annovis Bio, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-04-02Michael B HoffmanBuy$2.10713,800$1.5M
2025-12-08Michael B HoffmanBuy$4.3145,000$193,950
2025-11-24Michael B HoffmanBuy$4.0839,200$159,936
2025-11-21Michael B HoffmanBuy$3.5020,000$70,000
2025-11-14Michael B HoffmanBuy$2.1115,000$31,650
2025-10-28Maria-Luisa MaccecchiniBuy$2.0597,561$200,000
2025-10-28Michael B HoffmanBuy$2.05975,610$2.0M

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

ANVS shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns ANVS

Institutional investors own 22.2% of Annovis Bio's shares and insiders 11.79%. The largest holder is Empery Asset Management, LP with 5.63% of the shares (2.4M), as of June 30, 2026. Among the top 20 institutions, 14 added shares and 3 reduced their stake in the latest filings. Short interest is 15.66% of the float, or 4.29 days of average trading volume. The share count rose 263.9% since 2018.

Related: ANVS analyst forecast, ANVS key metrics. See the ANVS stock overview for the latest quote and news.

ANVS ownership FAQ

Who owns the most Annovis Bio stock?

The largest shareholders of Annovis Bio are Empery Asset Management, LP (5.63%), Marshall Wace Asset Management Ltd (4.32%), Vanguard Capital Management, LLC (3.86%), Tudor Investment Corp Et AL (3.18%), Renaissance Technologies Corp (2.35%).

What percentage of Annovis Bio is owned by institutions?

Institutions hold 22.2% of Annovis Bio's shares outstanding; insiders hold 11.79%.

Which funds own Annovis Bio?

The largest fund holders of Annovis Bio are Vanguard MStar Total Stk Mkt Idx Invest (2.86%), Fidelity Extended Market Index (0.36%), iShares Micro-Cap ETF (0.23%), Fidelity Series Total Market Index (0.11%), Fidelity Total Market Index (0.10%).

What is Annovis Bio's short interest?

5.9M shares of Annovis Bio were sold short, 15.66% of the float; at the average daily volume it would take 4.29 days to cover.

Are insiders buying or selling Annovis Bio?

Of the latest 7 reported insider transactions in Annovis Bio (since October 28, 2025), 7 were purchases and 0 were sales.

How many shares of Annovis Bio are outstanding?

Annovis Bio has 42.7M shares outstanding, of which 37.9M are in the public float.

Biotechnology: ownership