Annovis Bio, Inc. (ANVS) Key Metrics

NYSE: ANVSValuation, returns, debt and efficiency ratios over 10 years.

ANVS valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$42.4M
Enterprise value
$35.5M
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
—
Price / book
25.2
EV / EBITDA
—
Dividend yield
—
Beta
1.23

ANVS key metrics, 2012–2025

Fiscal year ended December 31, 2025 · U.S. dollars

ANVS valuation Price multiples at each fiscal year-end price.

Price / book−36.2%
4.2
2025 · hover or tap a bar for each year
2024: 6.62025: 4.2 (−36.2%)
20122025
Free cash flow yield−0.5 pts
−36.0%
2025 · hover or tap a bar for each year
2023: −23.7%2024: −35.6% (−11.9 pts)2025: −36.0% (−0.5 pts)
20122025

ANVS valuation history

Fiscal year-endToday10-year median

ANVS returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

ANVS debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

ANVS price vs earnings per share

Share price at year-endEPS (right axis)

ANVS key metrics

2012–2025
Annovis Bio, Inc. key metrics by fiscal year
2025202420232022202120202019201820172012
Valuation
Market capitalization$71.1M$61.5M$168.7M———————
Enterprise value$51.6M$51.0M$163.0M———————
Price / book4.26.6————————
Earnings yield−40.6%−40.0%−33.3%———————
Free cash flow yield−36.0%−35.6%−23.7%———————
Share price at fiscal year-end$3.46$5.03$18.70$13.43$17.58$7.54————
Per share
Revenue per share$0.00$0.00$0.00———————
Earnings per share−$1.40−$2.01−$6.23———————
Operating cash flow per share−$1.25−$1.79−$4.43———————
Free cash flow per share−$1.25−$1.79−$4.43———————
Cash per share$0.95$0.86$0.64———————
Book value per share$0.82$0.76−$0.86———————
Tangible book value per share$0.82$0.76−$0.86———————
Capex per share$0.00$0.00$0.00———————
Shares outstanding20.6M12.2M9.0M———————
Change in shares outstanding+68.0%+35.6%————————
Returns & profitability
Return on equity (ROE)−220.6%——−69.1%−55.7%————−100.4%
Return on invested capital (ROIC)—————————−18.5%
Return on assets (ROA)−164.8%−203.8%−243.1%−61.3%−53.5%−118.3%−169.7%−349.1%−42.7%−69.8%
Return on tangible assets−136.9%−176.6%−550.6%−69.8%−31.5%−67.3%−88.7%—−190.6%−502.1%
Free cash flow margin—————————−805.9%
Financial health
Total debt——————$499,807———
Cash & short-term investments$19.5M$10.6M$5.8M$28.4M$45.7M$8.1M$1,858$35,312$347,472$72,316
Net debt−$19.5M−$10.6M−$5.8M−$28.4M−$45.7M−$8.1M$497,949−$35,312−$347,472−$72,316
Debt / assets——————0.45———
Current ratio5.803.592.394.6830.5414.040.370.090.739.14
Quick ratio5.803.592.394.6830.5414.04371.200.090.739.01
Interest coverage—-14.4—-139.6—-0.1-0.0———
Working capital$17.4M$10.0M$5.9M$28.3M$44.5M$7.5M−$1.3M−$516,951−$132,257$1.4M
Invested capital−$2.7M−$1.2M−$13.5M−$54,163−$1.2M−$533,704−$8.1M−$7.6M−$7.3M$2.6M
Tangible asset value$16.9M$9.3M−$7.8M$28.3M$44.5M$7.5M−$8.6M−$7.6M−$7.0M$1.5M
Net current asset value$16.9M$9.3M−$7.8M$28.3M$44.5M$7.5M−$8.9M−$7.6M−$7.0M$1.4M
Graham net-net per share$0.74$0.48−$1.35———————
Capital allocation
Share buybacks (net)————$0$0—$0$0$0
Capex / revenue—————————43.0%
Capex / depreciation——4.000.000.000.000.000.000.005.39
SG&A / revenue—————————1,051.9%
Efficiency
Days sales outstanding—————————6,429.4
Days of inventory on hand—————————84,072.3
Days payables outstanding—————————114,124.0
Cash conversion cycle (days)—————————-23,622.4
Receivables turnover——————0.00——0.06
Payables turnover—————————0.00
Inventory turnover—————————0.00
Asset turnover0.000.000.000.000.000.000.000.000.000.02
Average receivables——————$735,075——$3.3M
Average payables$2.4M$1.8M$2.6M$2.3M$514,965$787,866$651,151$69,766$122,735$3.6M
Average inventory——————−$745.6M——$2.6M
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%41.5%

Computed from ANVS's annual financial statements (latest annual report filed March 13, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

ANVS valuation and financial ratios

Annovis Bio earned a return on equity of −220.6% in fiscal 2025.

See the ANVS income statement, the ANVS chart for price history, or the ANVS stock overview for the latest quote and news.

ANVS key metrics FAQ

What is Annovis Bio's return on equity?

Annovis Bio's return on equity (ROE) was −220.6% in fiscal 2025: net income of -$28.9 million on average shareholders' equity of $13.1 million.

What is Annovis Bio's free cash flow yield?

Annovis Bio generated -$25.6 million of free cash flow in fiscal 2025, a free cash flow yield of −36.0% on its market value at year-end ($71.1 million).

What is Annovis Bio's current ratio?

Annovis Bio's current ratio was 5.80 at the end of fiscal 2025: current assets were 5.80 times current liabilities.

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