Annexon, Inc. (ANNX) Ownership

NASDAQ: ANNXTop holders, insider trades and short interest.

ANNX ownership summary

as of October 18, 2026
Institutions
103.4%
of shares outstanding
Insiders
0.44%
of shares outstanding
Shares outstanding
189.6M
Float
163.8M
shares available to trade
Short interest
17.87%
32.0M shares short
Days to cover
9.94
short interest down 2.6% vs prior month
  • Institutions 103.41%
  • Insiders 0.44%

ANNX top institutional holders

20 largest
Annexon, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1FMR Inc10.30%19.5M$66.6M+8.9M (+83.5%)June 30, 2026
2BlackRock Inc7.14%13.5M$46.2M+2.6M (+23.8%)June 30, 2026
3Redmile Group, LLC6.26%11.9M$40.5M−2.7M (−18.4%)June 30, 2026
4State Street Corp5.18%9.8M$33.5M+2.9M (+42.0%)June 30, 2026
5Bvf Inc4.59%8.7M$29.7M—June 30, 2026
6Woodline Partners LP3.65%6.9M$23.6M+4.6M (+196.3%)June 30, 2026
7Vanguard Capital Management, LLC3.62%6.9M$23.4M+914,426 (+15.4%)June 30, 2026
8Mak Capital One LLC3.09%5.9M$20.0M+1.1M (+24.1%)June 30, 2026
9The Goldman Sachs Group Inc3.07%5.8M$19.9M+3.7M (+170.6%)June 30, 2026
10Siren, L.L.C.2.35%4.5M$15.2M+500,000 (+12.6%)June 30, 2026
11Bain Capital Life Sciences Investors, LLC2.34%4.4M$15.1M−774,943 (−14.9%)June 30, 2026
12Bellevue Group AG2.16%4.1M$14.0M−1.1M (−20.5%)June 30, 2026
13Geode Capital Management, LLC2.13%4.0M$13.8M+659,370 (+19.5%)June 30, 2026
14MPM Oncology Impact Management LP1.87%3.5M$12.1M+3.5M (0.0%)June 30, 2026
15Ameriprise Financial Inc1.85%3.5M$12.0M+60,502 (+1.8%)June 30, 2026
16Great Point Partners LLC1.85%3.5M$11.9M+1.0M (+40.0%)June 30, 2026
17Adage Capital Partners Gp LLC1.85%3.5M$11.9M−800,000 (−18.6%)June 30, 2026
18Morgan Stanley - Brokerage Accounts1.66%3.1M$10.7M+408,483 (+14.9%)June 30, 2026
19Palo Alto Investors, LLC1.56%2.9M$10.1M—June 30, 2026
20Balyasny Asset Management LLC1.49%2.8M$9.7M−1.1M (−27.2%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 13 holders added 30.9M shares and 5 cut 6.4M.

ANNX top mutual fund and ETF holders

20 largest
Annexon, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Fidelity Select Biotechnology3.26%6.2M$21.1M—August 31, 2026
2State Street® SPDR® S&P® Biotech ETF3.10%5.9M$20.1M−112,500 (−1.9%)September 30, 2026
3Vanguard MStar Total Stk Mkt Idx Invest2.62%5.0M$16.9M—August 31, 2026
4iShares Russell 2000 ETF2.15%4.1M$13.9M−47,040 (−1.1%)September 30, 2026
5Fidelity Stock Selector Small Cap1.09%2.1M$7.1M+446,900 (+27.6%)July 31, 2026
6Columbia Acorn Inst0.96%1.8M$6.2M—August 31, 2026
7Fidelity Small Cap Growth0.94%1.8M$6.1M+547,394 (+44.1%)July 31, 2026
8Fidelity Small Cap Index0.89%1.7M$5.8M+11,859 (+0.7%)July 31, 2026
9Fidelity Advisor Biotechnology I0.88%1.7M$5.7M—August 31, 2026
10iShares Russell 2000 Growth ETF0.78%1.5M$5.0M−1,865 (−0.1%)September 30, 2026
11Columbia Small Cap Value Discv A0.74%1.4M$4.8M+8,800 (+0.6%)August 31, 2026
12Strategic Advisers Fidelity US TtlStk0.69%1.3M$4.5M+203,676 (+18.5%)August 31, 2026
13iShares Biotechnology ETF0.68%1.3M$4.4M−9,720 (−0.8%)September 30, 2026
14Columbia Small Cap Growth Inst0.64%1.2M$4.2M—August 31, 2026
15Fidelity Select Health Care0.63%1.2M$4.1M—August 31, 2026
16Fidelity Series Small Cap Opps0.63%1.2M$4.0M+78,500 (+7.1%)July 31, 2026
17Fidelity Enhanced Small Cap Core ETF0.57%1.1M$3.7M+2,256 (+0.2%)September 30, 2026
18CREF Total Global Stock Account R30.54%1.0M$3.5M+181,220 (+21.6%)July 31, 2026
19Fidelity Select Pharmaceuticals Port0.53%1.0M$3.4M—August 31, 2026
20Foord International B0.53%1.0M$3.4M+1.0M (0.0%)June 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

ANNX insider transactions

latest 20
Annexon, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-04-10William H CarsonBuy$6.208,000$49,600
2026-03-10William H CarsonBuy$5.678,000$45,360
2026-02-18Dean Richard ArtisSell$5.105,290$26,979
2026-02-18Jamie DananbergSell$5.105,290$26,979
2026-02-18Jennifer LewSell$5.117,851$40,119
2026-02-18Michael OverdorfSell$5.106,225$31,747
2026-02-18Ted YednockSell$5.117,857$40,149
2025-12-30William H CarsonBuy$5.024,115$20,657
2025-12-01Jung ChoiBuy$4.1933,000$138,270
2025-12-01William H CarsonBuy$4.474,115$18,394
2025-11-21Muneer A SatterBuy$4.28422,613$1.8M
2025-11-20Muneer A SatterBuy$4.48400,000$1.8M
2025-11-19Muneer A SatterBuy$3.94500,000$2.0M
2025-11-17Muneer A SatterBuy$2.99500,000$1.5M
2025-10-30William H CarsonBuy$3.174,115$13,045
2025-09-30William H CarsonBuy$3.054,115$12,551
2025-07-30William H CarsonBuy$2.434,115$9,999
2025-07-14Jennifer LewSell$2.581,117$2,882
2025-07-14Jennifer LewSell$2.581,117$2,882
2025-07-14Michael OverdorfSell$2.61853$2,226

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

ANNX shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns ANNX

Institutional investors own 103.4% of Annexon's shares and insiders 0.44%. The largest holder is FMR Inc with 10.30% of the shares (19.5M), as of June 30, 2026. Among the top 20 institutions, 13 added shares and 5 reduced their stake in the latest filings. Short interest is 17.87% of the float, or 9.94 days of average trading volume. The share count rose 35,754.3% since 2018.

Related: ANNX analyst forecast, ANNX key metrics. See the ANNX stock overview for the latest quote and news.

ANNX ownership FAQ

Who owns the most Annexon stock?

The largest shareholders of Annexon are FMR Inc (10.30%), BlackRock Inc (7.14%), Redmile Group, LLC (6.26%), State Street Corp (5.18%), Bvf Inc (4.59%).

What percentage of Annexon is owned by institutions?

Institutions hold 103.4% of Annexon's shares outstanding; insiders hold 0.44%.

Which funds own Annexon?

The largest fund holders of Annexon are Fidelity Select Biotechnology (3.26%), State Street® SPDR® S&P® Biotech ETF (3.10%), Vanguard MStar Total Stk Mkt Idx Invest (2.62%), iShares Russell 2000 ETF (2.15%), Fidelity Stock Selector Small Cap (1.09%).

What is Annexon's short interest?

32.0M shares of Annexon were sold short, 17.87% of the float; at the average daily volume it would take 9.94 days to cover.

Are insiders buying or selling Annexon?

Of the latest 20 reported insider transactions in Annexon (since July 14, 2025), 12 were purchases and 8 were sales.

How many shares of Annexon are outstanding?

Annexon has 189.6M shares outstanding, of which 163.8M are in the public float.

Biotechnology: ownership