Annexon, Inc. (ANNX) Cash Flow Statement
Where ANNX’s cash came from and went, 2025
December 31, 2025 · U.S. dollars- Cash from operations
- −$186.4M
- Capital expenditures
- $137,000
- Free cash flow
- −$186.5M
- Returned to shareholders
- $1.9M
- Change in cash
- $112.6M cash at year-end $163.1M
Drawn to scale: where the cash came from and how it was used. Hover for values.
ANNX operating cash flow, capex and free cash flow
ANNX cash flow trends, 2017–2025
| Metric | Trend | Then | Latest | Change |
|---|---|---|---|---|
| Operating cash flow | −$19.3M2017 | −$186.4M2025 | — | |
| Capital expenditures | $567,0002017 | $137,0002025 | −16.3%/yr | |
| Free cash flow | −$19.8M2017 | −$186.5M2025 | — | |
| Stock-based compensation | $401,0002017 | $16.4M2025 | +59.1%/yr | |
| Dividends paid | $102.5M2020 | $1.9M2025 | −55.2%/yr | |
| Share buybacks (net) | $02017 | $02022 | — |
Change is the average annual growth (CAGR) or the difference between the first and latest year.
ANNX cash flow by activity
ANNX net income vs operating cash flow
Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).
ANNX cash flow statement
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|
| Operating activities | |||||||||
| Net income | −$206.7M | −$138.2M | −$134.2M | −$141.9M | −$130.3M | −$63.4M | −$37.2M | −$18.3M | −$18.7M |
| Depreciation & amortization | $2.2M | $2.1M | $2.1M | $2.1M | $2.1M | $667,000 | $493,000 | $488,000 | $271,000 |
| Stock-based compensation | $16.4M | $19.4M | $18.2M | $18.5M | $16.3M | $4.9M | $2.0M | $408,000 | $401,000 |
| Change in working capital | $4.2M | $6.4M | −$5.8M | $3.7M | $3.3M | $4.7M | $625,000 | $478,000 | −$1.2M |
| Other non-cash items | −$2.5M | −$7.8M | −$1.4M | $1.3M | $2.5M | $53,000 | $5.7M | −$260,000 | $0 |
| Cash from operating activities | −$186.4M | −$118.0M | −$121.1M | −$116.3M | −$106.1M | −$53.1M | −$28.4M | −$17.2M | −$19.3M |
| Investing activities | |||||||||
| Capital expenditures | −$137,000 | −$15,000 | −$193,000 | −$6.5M | −$1.7M | −$464,000 | −$267,000 | −$17,000 | −$567,000 |
| Investments (net) | $190.2M | −$218.8M | $29.3M | $65.0M | −$86.6M | −$83.2M | −$267,000 | −$17,000 | −$82.7M |
| Acquisitions & other investing | $0 | $15,000 | $41.6M | $0 | $0 | $464,000 | $267,000 | $17,000 | $82.7M |
| Cash from investing activities | $190.1M | −$218.8M | $70.7M | $58.4M | −$88.2M | −$83.2M | −$267,000 | −$17,000 | −$567,000 |
| Financing activities | |||||||||
| Dividends paid | −$1.9M | — | — | — | — | −$102.5M | — | — | — |
| Share repurchases & issuance (net) | — | — | — | $121.4M | $1.8M | −$5.2M | $30.0M | $58.5M | $42,000 |
| Net borrowing (repayment) | — | — | — | — | $0 | — | — | — | — |
| Shares issued | $109.6M | $161.9M | $17.5M | $130.5M | $0 | $369.0M | $30.0M | $58.3M | $0 |
| Other financing | $1.2M | −$665,000 | $118.0M | −$129.0M | $0 | $99.6M | −$31.6M | −$58.3M | $0 |
| Cash from financing activities | $108.9M | $161.2M | $135.5M | $122.9M | $1.8M | $360.9M | $28.4M | $58.5M | $42,000 |
| Summary | |||||||||
| Net change in cash | $112.6M | −$175.6M | $85.1M | $65.0M | −$193.7M | $224.6M | −$244,000 | $41.2M | −$19.8M |
| Cash at end of period | $163.1M | $50.5M | $226.1M | $141.1M | $74.8M | $268.6M | $43.9M | $44.2M | $3.0M |
| Free cash flow | −$186.5M | −$118.0M | −$121.3M | −$122.8M | −$107.8M | −$53.6M | −$28.6M | −$17.2M | −$19.8M |
| Jun '26 | Mar '26 | Dec '25 | Sep '25 | Jun '25 | Mar '25 | Dec '24 | Sep '24 | Jun '24 | Mar '24 | Dec '23 | Sep '23 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating activities | ||||||||||||
| Net income | −$55.3M | −$44.1M | −$48.3M | −$54.9M | −$49.2M | −$54.4M | −$48.6M | −$34.8M | −$29.6M | −$25.2M | −$27.9M | −$32.5M |
| Depreciation & amortization | $540,000 | $539,000 | $543,000 | $546,000 | $540,000 | $537,000 | $537,000 | $538,000 | $537,000 | $538,000 | $538,000 | $538,000 |
| Stock-based compensation | $4.8M | $4.2M | $3.3M | $3.8M | $4.2M | $5.1M | $5.2M | $4.6M | $4.9M | $4.7M | $4.4M | $4.5M |
| Change in working capital | $12.6M | −$7.1M | −$1.5M | −$1.7M | $7.2M | $177,000 | $9.5M | $430,000 | $3.9M | −$7.5M | −$527,000 | −$586,000 |
| Other non-cash items | −$10.6M | −$214,000 | −$22,000 | −$88,000 | −$884,000 | −$1.5M | −$2.7M | −$2.8M | −$1.5M | −$829,000 | $36,000 | −$310,000 |
| Cash from operating activities | −$48.0M | −$46.8M | −$45.9M | −$52.3M | −$38.1M | −$50.1M | −$36.0M | −$32.0M | −$21.7M | −$28.3M | −$23.5M | −$28.3M |
| Investing activities | ||||||||||||
| Capital expenditures | −$137,000 | $0 | $0 | −$48,000 | −$15,000 | −$74,000 | −$6,000 | −$9,000 | $0 | $0 | −$7,000 | −$19,000 |
| Investments (net) | $40.1M | $27.1M | −$26.5M | $45.9M | $73.1M | $97.6M | $1.0M | −$45.9M | −$96.6M | −$77.3M | −$2.2M | $47.8M |
| Acquisitions & other investing | $0 | $0 | $0 | $48,000 | $15,000 | $74,000 | $6,000 | $9,000 | $0 | $0 | $7,000 | $19,000 |
| Cash from investing activities | $40.0M | $27.1M | −$26.5M | $45.9M | $73.1M | $97.6M | $1.0M | −$45.9M | −$96.6M | −$77.3M | −$2.2M | $47.8M |
| Financing activities | ||||||||||||
| Dividends paid | — | — | −$1.9M | — | — | — | — | — | — | — | — | — |
| Share repurchases & issuance (net) | — | — | — | — | — | — | — | — | — | — | −$9.34B | $9.34B |
| Shares issued | $32.2M | $33.6M | $95.4M | $14.2M | $0 | $0 | $4.6M | $0 | $124.1M | $33.1M | $118.0M | $0 |
| Other financing | −$59,000 | −$707,000 | $1.6M | −$625,000 | $153,000 | $59,000 | $333,000 | $175,000 | −$454,000 | −$719,000 | $9.33B | $0 |
| Cash from financing activities | $32.1M | $32.9M | $95.1M | $13.6M | $153,000 | $59,000 | $5.0M | $175,000 | $123.7M | $32.4M | $117.6M | $9.34B |
| Summary | ||||||||||||
| Net change in cash | $24.1M | $13.2M | $22.6M | $7.1M | $35.2M | $47.6M | −$30.0M | −$77.8M | $5.4M | −$73.2M | $92.0M | $19.5M |
| Cash at end of period | $200.3M | $176.2M | $163.1M | $140.5M | $133.3M | $98.2M | $50.5M | $80.6M | $157.3M | $153.0M | $225.1M | $134.2M |
| Free cash flow | −$48.1M | −$46.8M | −$45.9M | −$52.4M | −$38.1M | −$50.1M | −$36.0M | −$32.0M | −$21.7M | −$28.3M | −$23.5M | −$28.3M |
| Free cash flow margin | — | — | — | — | — | — | −1,058.2% | — | — | — | −482.6% | — |
| Capex / revenue | — | — | — | — | — | — | 0.2% | — | — | — | 0.1% | — |
Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.
ANNX cash generation
In fiscal 2025 (ended December 31, 2025), Annexon generated -$186.4 million of cash from operations and spent $0.1 million on capital expenditures, leaving free cash flow of -$186.5 million. It returned $1.9 million to shareholders through dividends ($1.9 million) and net share buybacks ($0). Cash and equivalents rose by $112.6 million over the year.
Related: ANNX income statement, ANNX balance sheet. See the ANNX stock overview for the latest quote and news.
ANNX cash flow FAQ
What is Annexon's free cash flow?
Annexon's free cash flow was -$186.5 million in fiscal 2025: -$186.4 million of operating cash flow minus $0.1 million of capital expenditures It was -$118.0 million a year earlier..
How much cash does Annexon generate from operations?
Annexon generated -$186.4 million of cash from operating activities in fiscal 2025.
How much does Annexon spend on capital expenditures?
Annexon spent $0.1 million on capital expenditures in fiscal 2025, compared with $0.0 million the year before.
How much does Annexon pay in dividends?
Annexon paid $1.9 million in dividends in fiscal 2025.