AC Immune SA (ACIU) Ownership

NASDAQ: ACIUTop holders, insider trades and short interest.

ACIU ownership summary

as of October 18, 2026
Institutions
24.3%
of shares outstanding
Insiders
38.09%
of shares outstanding
Shares outstanding
99.4M
Float
39.2M
shares available to trade
Short interest
7.59%
3.5M shares short
Days to cover
21.42
short interest up 1.4% vs prior month
  • Institutions 24.34%
  • Insiders 38.09%
  • Other investors 37.57%

ACIU top institutional holders

20 largest
AC Immune SA top institutional holders
#Holder% of sharesSharesValueChangeReported
1Bvf Inc19.94%19.8M$47.4M—June 30, 2026
2Wells Fargo & Co1.01%1.0M$2.4M−243 (−0.0%)June 30, 2026
3Renaissance Technologies Corp0.84%840K$2.0M+215,760 (+34.6%)June 30, 2026
4Millennium Management LLC0.78%774K$1.8M−19,063 (−2.4%)June 30, 2026
5BlackRock Inc0.52%519K$1.2M−5,004 (−1.0%)June 30, 2026
6Dimensional Fund Advisors, Inc.0.34%340K$812,796−50,083 (−12.8%)June 30, 2026
7Arrowstreet Capital Limited Partnership0.23%233K$556,758−172,705 (−42.6%)June 30, 2026
8Citadel Advisors Llc0.21%208K$496,178−59,627 (−22.3%)June 30, 2026
9Morgan Stanley - Brokerage Accounts0.13%132K$315,038+42,562 (+47.7%)June 30, 2026
10Two Sigma Investments LLC0.10%103K$245,752+63,734 (+163.0%)June 30, 2026
11Deeter Investments LLP0.10%100K$239,000—March 31, 2026
12Qube Research & Technologies0.09%92K$220,719+92,351 (0.0%)June 30, 2026
13UBS Group AG0.09%86K$204,617−16,015 (−15.8%)June 30, 2026
14Geode Capital Management, LLC0.06%62K$147,831−1,747 (−2.7%)June 30, 2026
15Susquehanna International Group, LLP0.05%53K$127,552−35,893 (−40.2%)June 30, 2026
16Jump Financial LLC0.02%24K$57,513+12,939 (+116.3%)June 30, 2026
17Jane Street Group LLC0.02%19K$46,545−38,221 (−66.2%)June 30, 2026
18Verdad Advisers, LP0.02%16K$38,957+16,300 (0.0%)June 30, 2026
19China Universal Asset Mgmt Co.Ltd0.02%16K$38,711−1,655 (−9.3%)June 30, 2026
20The Goldman Sachs Group Inc0.01%14K$34,648−7,135 (−33.0%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 6 holders added 444K shares and 12 cut 407K.

ACIU top mutual fund and ETF holders

20 largest
AC Immune SA top fund holders
#Holder% of sharesSharesValueChangeReported
1iShares Biotechnology ETF0.48%478K$1.1M−3,624 (−0.8%)September 30, 2026
2Monega ARIAD Innovation R0.09%92K$220,738—August 31, 2026
3Dimensional US Small Cap ETF0.08%81K$192,971—September 30, 2026
4iShares Nasdaq US Biotech ETF USD Acc0.08%80K$191,661+696 (+0.9%)September 30, 2026
5Fidelity Nasdaq Composite Index0.07%70K$166,942—August 31, 2026
6DFA US Small Cap I0.05%45K$108,477—August 31, 2026
7DFA US Micro Cap I0.04%44K$105,332—August 31, 2026
8Top Class Healthcare FI0.04%40K$95,600—August 31, 2026
9China Universal NASDAQ Bio-Tch ETF(QDII)0.02%16K$38,711−165 (−1.0%)June 30, 2026
10DFA US Vector Equity I0.02%16K$37,812—August 31, 2026
11Dimensional Global Small Coms USD Acc0.01%12K$29,165—August 31, 2026
12Dimensional World Equity GBP Acc0.01%12K$28,615—August 31, 2026
13Dimensional Gl Cor Eq LC ESG Sc USD A0.01%9,976$23,843—August 31, 2026
14Dimensional International Core Eq Acc0.01%9,822$23,475—August 31, 2026
15JNL/DFA US Small Cap A0.01%7,966$19,039—June 30, 2026
16Dimensional US Core Equity 2 ETF0.01%7,863$18,793—September 30, 2026
17Dimensional World Allc 60/40 GBP Acc0.01%7,854$18,771—August 31, 2026
18Invesco Nasdaq Biotechnology ETF0.01%7,184$17,170+322 (+4.7%)September 30, 2026
19Dimensional US Sm Company EUR Acc0.01%7,000$16,730—August 31, 2026
20Dimensional US Core Equity 1 ETF0.01%5,748$13,738—September 24, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

ACIU shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns ACIU

Institutional investors own 24.3% of AC Immune's shares and insiders 38.09%. The largest holder is Bvf Inc with 19.94% of the shares (19.8M), as of June 30, 2026. Among the top 20 institutions, 6 added shares and 12 reduced their stake in the latest filings. Short interest is 7.59% of the float, or 21.42 days of average trading volume. The share count rose 86.8% since 2014.

Related: ACIU analyst forecast, ACIU key metrics. See the ACIU stock overview for the latest quote and news.

ACIU ownership FAQ

Who owns the most AC Immune stock?

The largest shareholders of AC Immune are Bvf Inc (19.94%), Wells Fargo & Co (1.01%), Renaissance Technologies Corp (0.84%), Millennium Management LLC (0.78%), BlackRock Inc (0.52%).

What percentage of AC Immune is owned by institutions?

Institutions hold 24.3% of AC Immune's shares outstanding; insiders hold 38.09%.

Which funds own AC Immune?

The largest fund holders of AC Immune are iShares Biotechnology ETF (0.48%), Monega ARIAD Innovation R (0.09%), Dimensional US Small Cap ETF (0.08%), iShares Nasdaq US Biotech ETF USD Acc (0.08%), Fidelity Nasdaq Composite Index (0.07%).

What is AC Immune's short interest?

3.5M shares of AC Immune were sold short, 7.59% of the float; at the average daily volume it would take 21.42 days to cover.

How many shares of AC Immune are outstanding?

AC Immune has 99.4M shares outstanding, of which 39.2M are in the public float.

Biotechnology: ownership