Aprea Therapeutics, Inc. (APRE) Key Metrics

NASDAQ: APREValuation, returns, debt and efficiency ratios over 10 years.

APRE valuation today

Trailing 12 months · as of October 17, 2026
Market cap
$7.4M
Enterprise value
−$31.4M
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
—
10-yr median 19.5
Price / book
0.3
10-yr median 0.9
EV / EBITDA
0.3
Dividend yield
—
Beta
1.63

APRE key metrics, 2013–2025

Fiscal year ended December 31, 2025 · U.S. dollars

APRE valuation Price multiples at each fiscal year-end price.

Price / sales+61.8%
19.5
2025 · hover or tap a bar for each year
2023: 29.22024: 12.1 (−58.6%)2025: 19.5 (+61.8%)
20132025
Price / book−52.3%
0.4
2025 · hover or tap a bar for each year
2023: 0.92024: 0.9 (+0.9%)2025: 0.4 (−52.3%)
20132025
Free cash flow yield−156.3 pts
−231.2%
2025 · hover or tap a bar for each year
2023: −72.2%2024: −74.9% (−2.7 pts)2025: −231.2% (−156.3 pts)
20132025

APRE valuation history

Fiscal year-endToday10-year median

APRE returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

APRE debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

APRE price vs earnings per share

Share price at year-endEPS (right axis)

APRE key metrics

2013–2025
Aprea Therapeutics, Inc. key metrics by fiscal year
2025202420232022202120202019201820172013
Valuation
Market capitalization$5.6M$18.1M$17.0M———————
Enterprise value−$9.0M−$4.7M−$4.6M———————
Price / sales19.512.129.2———————
Price / book0.40.90.9———————
EV / sales-31.6-3.1-7.9———————
Earnings yield−225.9%−71.5%−84.0%———————
Free cash flow yield−231.2%−74.9%−72.2%———————
Share price at fiscal year-end$0.85$3.29$4.70$6.62$57.40$98.40$917.80———
Per share
Revenue per share$0.04$0.27$0.16———————
Earnings per share−$1.93−$2.35−$3.95———————
Operating cash flow per share−$1.97−$2.46−$3.37———————
Free cash flow per share−$1.97−$2.46−$3.39———————
Cash per share$2.23$4.15$5.97———————
Book value per share$1.90$3.50$5.05———————
Tangible book value per share$1.90$3.50$5.05———————
Capex per share$0.00$0.00$0.03———————
Shares outstanding6.5M5.5M3.6M———————
Change in shares outstanding+18.7%+52.3%————————
Returns & profitability
Return on equity (ROE)−79.4%−69.0%−65.1%−299.8%−57.6%−53.5%−77.1%———
Return on assets (ROA)−63.1%−55.6%−54.1%−259.1%−48.8%−47.6%−28.1%−34.2%−61.3%—
Return on tangible assets−79.1%−54.0%−63.1%−373.6%−64.3%−58.1%−21.0%−23.5%−61.3%—
Free cash flow margin—−903.3%————————
Financial health
Total debt————$190,471$335,156$544,950$0$0$1.5M
Cash & short-term investments$14.6M$22.8M$21.6M$28.8M$53.1M$89.0M$130.1M$65.7M$24.4M—
Net debt−$14.6M−$22.8M−$21.6M−$28.8M−$52.9M−$88.7M−$129.5M−$65.7M−$24.4M$1.5M
Debt / equity————0.000.000.00———
Debt / assets————0.000.000.000.000.00—
Current ratio5.637.015.149.427.736.0314.6813.565.75—
Quick ratio5.637.015.149.427.736.0314.6813.565.75—
Interest coverage———-252.7—-237.2-189.0———
Working capital$12.8M$20.2M$18.1M$27.0M$49.3M$77.1M$124.0M$61.1M$20.4M—
Invested capital−$2.2M−$3.5M−$3.3M−$3.1M−$3.4M−$11.3M−$5.3M−$117.1M−$60.2M—
Tangible asset value$12.4M$19.3M$18.3M$25.6M$49.5M$77.4M$124.2M−$51.4M−$35.8M—
Net current asset value$12.1M$18.9M$18.1M$25.6M$49.3M$77.0M$123.7M−$51.5M−$35.8M—
Graham net-net per share$1.70$3.30$4.76———————
Capital allocation
Dividends paid———————$0$0—
Share buybacks (net)——————$0$0$0—
Capex / revenue0.0%1.0%16.0%———————
Capex / depreciation0.000.6913.200.000.000.110.180.450.47—
Stock-based compensation / revenue167.3%32.6%76.2%———————
R&D / revenue2,464.7%623.2%1,307.8%———————
SG&A / revenue2,266.4%429.8%1,446.2%———————
Efficiency
Days payables outstanding17,362.658.965,037.629.14,216.45,309.84,197.974,640.4135,268.8—
Payables turnover0.026.200.0112.540.090.070.090.000.000.00
Asset turnover0.010.060.020.000.000.000.000.000.00—
Average payables$1.0M$1.5M$1.3M$1.3M$3.1M$3.3M$2.0M$1.7M$2.9M$4.0M
Average inventory———————$0$0—
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%—

Computed from APRE's annual financial statements (latest annual report filed March 16, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

APRE valuation and financial ratios

Aprea Therapeutics earned a return on equity of −79.4% in fiscal 2025.

See the APRE income statement, the APRE chart for price history, or the APRE stock overview for the latest quote and news.

APRE key metrics FAQ

What is Aprea Therapeutics's return on equity?

Aprea Therapeutics's return on equity (ROE) was −79.4% in fiscal 2025: net income of -$12.6 million on average shareholders' equity of $15.9 million.

What is Aprea Therapeutics's free cash flow yield?

Aprea Therapeutics generated -$12.9 million of free cash flow in fiscal 2025, a free cash flow yield of −231.2% on its market value at year-end ($5.6 million).

What is Aprea Therapeutics's current ratio?

Aprea Therapeutics's current ratio was 5.63 at the end of fiscal 2025: current assets were 5.63 times current liabilities.

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