Aprea Therapeutics, Inc. (APRE) Cash Flow Statement

NASDAQ: APREOperating cash, capex, free cash flow and buybacks.

Where APRE’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$12.9M
Capital expenditures
$0
0.0% of revenue
Free cash flow
−$12.9M
−4,512.3% margin
Returned to shareholders
—
Change in cash
−$8.2M
cash at year-end $14.6M
Shares issued: $5.0MShares issued$5.0MDrawn from cash: $8.2MDrawn from cash$8.2MCash used in operations: $12.9MCash used in operations$12.9M · 97%Other financing: $407,368Other financing$407,368 · 3%$13.3M
Cash from operations
−$12.9M
Shares issued
+$5.0M
Other financing
−$407,368
Change in cash
−$8.2M

Drawn to scale: where the cash came from and how it was used. Hover for values.

APRE operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

APRE cash flow trends, 2017–2025

Aprea Therapeutics, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$14.0M2017−$12.9M2025—
Capital expenditures$3,7022017$02025−100.0%
Free cash flow−$14.0M2017−$12.9M2025—
Free cash flow margin−2,103.9%2023−4,512.3%2025−2,408.4 pts
Stock-based compensation$395,4402017$478,1412025+2.4%/yr
Dividends paid$02017$02018—
Share buybacks (net)$02017$02019—
Capex / revenue16.0%20230.0%2025−16.0 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

APRE cash flow by activity

OperatingInvestingFinancingChange in cash

APRE net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

APRE cash flow statement

Aprea Therapeutics, Inc. annual cash flow statement
202520242023202220212020201920182017
Operating activities
Net income−$12.6M−$13.0M−$14.3M−$112.7M−$37.1M−$53.5M−$28.1M−$15.5M−$15.2M
Depreciation & amortization$21,715$22,318$7,052$186,445$271,677$229,610$170,254$8,316$7,932
Stock-based compensation$478,141$489,436$444,459$17.0M$7.8M$5.0M$1.3M$329,184$395,440
Change in working capital−$929,095−$1.1M$1.6M−$1.8M−$8.3M$5.6M$1.2M$901,851$1.4M
Other non-cash items$134,369−$54,365$38,926$72.2M−$317,402$890,252−$1.3M−$961,316−$662,140
Cash from operating activities−$12.9M−$13.6M−$12.2M−$25.0M−$37.7M−$41.8M−$26.7M−$15.3M−$14.0M
Investing activities
Capital expenditures$0−$15,478−$93,093$0$0−$25,709−$30,901−$3,702−$3,702
Investments (net)—−$15,478−$85,943$0−$16,290−$25,709−$30,901−$3,702$0
Acquisitions & other investing—$15,478$85,943——$25,709$30,901$3,702$0
Cash from investing activities—−$15,478−$93,093——−$25,709−$30,901−$3,702−$3,702
Financing activities
Dividends paid———————$0$0
Share repurchases & issuance (net)——————$92.6M$56.4M$23.3M
Net borrowing (repayment)———————$0$0
Shares issued$5.0M$16.1M$5.9M$682,973$1.5M$86.9M$92.5M$56.4M$0
Other financing−$407,368−$1.3M−$747,454$0$208,367−$86.8M−$92.5M−$56.4M$3
Cash from financing activities$4.6M$14.8M$5.1M$682,973$1.7M$150,949$92.6M$56.4M$23.3M
Summary
Net change in cash−$8.2M$1.2M−$7.1M−$24.3M−$35.9M−$41.1M$64.4M$41.3M$10.7M
Cash at end of period$14.6M$22.9M$21.6M$28.8M$53.1M$89.0M$130.1M$65.7M$24.4M
Free cash flow−$12.9M−$13.6M−$12.3M−$25.0M−$37.7M−$41.8M−$26.7M−$15.3M−$14.0M
Free cash flow margin−4,512.3%−903.3%−2,103.9%——————
Capex / revenue0.0%1.0%16.0%——————

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

APRE cash generation

In fiscal 2025 (ended December 31, 2025), Aprea Therapeutics generated -$12.9 million of cash from operations and spent $0 on capital expenditures, leaving free cash flow of -$12.9 million, −4,512.3% of revenue. Cash and equivalents fell by $8.2 million over the year.

Related: APRE income statement, APRE balance sheet. See the APRE stock overview for the latest quote and news.

APRE cash flow FAQ

What is Aprea Therapeutics's free cash flow?

Aprea Therapeutics's free cash flow was -$12.9 million in fiscal 2025: -$12.9 million of operating cash flow minus $0 of capital expenditures It was -$13.6 million a year earlier..

How much cash does Aprea Therapeutics generate from operations?

Aprea Therapeutics generated -$12.9 million of cash from operating activities in fiscal 2025.

Biotechnology: cash flow