SOPHiA GENETICS SA (SOPH) AI Stock Analysis

NASDAQ: SOPHAI research summary: business, growth, valuation, analysts, bull and bear case.

SOPH AI stock analysis summary

AI Research

SOPHiA GENETICS SA is a healthcare technology company providing data analysis solutions through its SOPHiA DDM platform. The company generated $86.2M in trailing twelve-month revenue with quarterly revenue growth of 27.2% as of June 30, 2026. However, it continues to post operating losses, recording an operating margin of -86.0% and net cash of $45.8M.

Market cap
$572.9M
Revenue (TTM)
$86.2M
P/E
—
1Y return
51.6%
S&P 500 16.8%
Avg. target
$9.75
44.9% vs last close

Bull case

  • The company delivered 27.2% year-over-year quarterly revenue growth in the period ending June 30, 2026.
  • Analyst sentiment remains positive with 5 StrongBuy ratings and an average price target of $9.75, representing 44.9% upside from the last close.
  • The balance sheet maintains net cash of $45.8M and a current ratio of 2.69 as of June 30, 2026.

Bear case

  • SOPHiA GENETICS remained unprofitable with a net income of -$79.0M in FY2025 and an EPS of -$1.16 for the trailing twelve months.
  • The business burned free cash flow of -$38.6M in FY2025 alongside an operating margin of -91.8%.
  • The stock trades at a price-to-sales multiple of 6.6x, compared to 4.1x for the median of its US-listed Healthcare peers.

What SOPHiA GENETICS does

SOPHiA GENETICS SA functions as a healthcare technology company specializing in advanced data analysis solutions. At the core of its offerings is the SOPHiA DDM platform, a cloud-based software-as-a-service tool designed to analyze extensive datasets and diagnostic modalities. This platform enables hospitals, laboratories, and biopharma entities to derive actionable insights from complex data. It facilitates the interpretation of multimodal datasets by integrating genomic, radiomic, and clinical data to enhance precision medicine initiatives. Founded in 2011 and headquartered in Saint-Sulpice, Switzerland, the company employs 415 people and utilizes artificial intelligence to advance patient care and therapeutic development.

Growth and profitability

Revenue expanded from $40.5M in FY2021 to $47.6M in FY2022, $62.4M in FY2023, $65.2M in FY2024, and reached $77.3M in FY2025, reflecting a 5-year revenue CAGR of 22.2%. Revenue growth in FY2025 was 18.6%, while gross margin stood at 61.9%. Operating margins remained negative across all reported periods, finishing at -91.8% in FY2025 alongside a net income of -$79.0M. For the trailing twelve months ending June 30, 2026, revenue totaled $86.2M with quarterly revenue growth of 27.2% year-over-year. The trailing twelve-month operating margin was -86.0%, profit margin was -93.9%, and diluted earnings per share stood at -$1.16.

SOPH income statement →

Balance sheet and cash flow

As of June 30, 2026, SOPHiA GENETICS held $107.7M in cash and short-term investments against total debt of $61.8M, yielding net cash of $45.8M. Total assets were $198.4M and shareholders' equity was $83.1M. The company reported a current ratio of 2.69 and a debt-to-equity ratio of 0.74. In FY2025, operating cash flow was -$38.0M and free cash flow was -$38.6M. Capital expenditures in FY2025 were $574,000, while the 5-year share count change was 23.9%.

SOPH balance sheet →

Valuation and performance

At a last close price of $6.73, SOPHiA GENETICS had a market capitalization of $572.9M and an enterprise value of $646.7M. The stock trades at a price-to-sales multiple of 6.6x and an EV to revenue multiple of 7.5x, above the median of its US-listed Healthcare peers of 4.1x for price-to-sales. Over the past year, the stock returned 51.6%, outperforming the S&P 500 return of 16.8%. Over a 5-year period, however, the shares declined 58.2%, trailing the S&P 500 return of 83.0%.

SOPH key metrics →

What analysts expect

All 5 analysts tracking SOPHiA GENETICS rate the stock a StrongBuy, with 0 Buy, 0 Hold, 0 Sell, and 0 StrongSell ratings. The mean price target is $9.75, which stands 44.9% above the last close price of $6.73. For the current fiscal year ending December 31, 2026, analysts estimate revenue of $95.2M and an EPS of -$0.85. The company beat EPS estimates in 2 of the last 4 quarters, and its next earnings date is November 3, 2026.

SOPH forecast and price target →

Key risks and what to watch

  • Ongoing cash burn is highlighted by FY2025 free cash flow of -$38.6M relative to $107.7M in cash and short-term investments.
  • Share dilution has occurred over time, with the share count increasing 23.9% over a 5-year period.
  • Long-term stock performance has lagged the broader market, posting a 5-year return of -58.2% compared to 83.0% for the S&P 500.

AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer

About this SOPH AI stock analysis

This page is an AI-written research summary of SOPHiA GENETICS SA (SOPH). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.

Related: SOPH income statement, SOPH balance sheet, SOPH key metrics, SOPH analyst forecast, SOPH chart. See the SOPH stock overview for the latest quote and news.

SOPH AI stock analysis FAQ

What is SOPHiA GENETICS' revenue growth rate?

SOPHiA GENETICS achieved a 5-year revenue CAGR of 22.2% from FY2020 to FY2025, with FY2025 revenue increasing 18.6% to $77.3M. In the latest quarter ended June 30, 2026, quarterly revenue grew 27.2% year-over-year.

Is SOPHiA GENETICS profitable?

No, the company is not profitable. It reported a net income of -$79.0M in FY2025 and a trailing twelve-month profit margin of -93.9%.

What do Wall Street analysts forecast for SOPH stock?

Analysts have an average price target of $9.75 for SOPH, representing 44.9% potential upside from its close of $6.73. All 5 covering analysts maintain a StrongBuy rating.

When does SOPHiA GENETICS report its next earnings?

The company is scheduled to report its next earnings on November 3, 2026. For the current fiscal year ending December 31, 2026, analysts estimate revenue of $95.2M and an EPS of -$0.85.

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