Tempus AI, Inc. (TEM) AI Stock Analysis

NASDAQ: TEMAI research summary: business, growth, valuation, analysts, bull and bear case.

TEM AI stock analysis summary

AI Research

Tempus AI, Inc. (TEM) applies artificial intelligence to precision medicine and healthcare data. The company has driven significant top-line expansion, growing revenue 83.4% in FY2025 to $1.27B while expanding gross margins to 62.7%. However, it remains unprofitable, recording a net income of -$245.0M in FY2025 and free cash flow of -$245.4M.

Market cap
$11.68B
Revenue (TTM)
$1.43B
P/E
—
1Y return
-28.9%
S&P 500 16.8%
Avg. target
$74.94
15.8% vs last close

Bull case

  • Revenue grew 83.4% in FY2025 to $1.27B, supported by widespread adoption of its platform by roughly 95% of the largest public pharmaceutical companies.
  • Gross margins expanded consistently from 32.4% in FY2021 to 62.7% in FY2025, reflecting higher product profitability.
  • Analysts project EPS to improve 58.7% to -$0.25 in FY2026 and reach -$0.05 in FY2027, backed by 4 consecutive quarters of earnings beats.

Bear case

  • The business remains unprofitable, generating a net loss of -$245.0M and negative free cash flow of -$245.4M in FY2025.
  • The balance sheet carries total debt of $1.44B and net debt of $628.2M, yielding a high debt-to-equity ratio of 3.25.
  • Valuation is elevated, with a price-to-sales multiple of 8.2x that doubles the US-listed Healthcare peer median of 4.1x.

What Tempus AI does

Tempus AI, Inc. Class A focuses on advancing precision medicine by integrating artificial intelligence into healthcare. Its core offering is Intelligent Diagnostics, which utilizes AI technologies, including generative AI, to improve the accuracy, personalization, and customization of laboratory tests. The company operates the Tempus Platform, an operating system and technology architecture created to break down healthcare data silos into actionable insights. This infrastructure has aggregated one of the world's largest clinical and molecular oncology data libraries. Tempus AI has commercialized a broad suite of products from this platform, which have been adopted by approximately 95% of the largest public pharmaceutical companies for research and clinical decisions.

Growth and profitability

Tempus AI grew revenue from $257.9M in FY2021 to $1.27B in FY2025, representing a 5-year revenue CAGR of 46.6% from FY2020 to FY2025. Annual revenue grew 83.4% in FY2025, following a 30.4% increase in FY2024. Gross margin improved from 32.4% in FY2021 to 62.7% in FY2025. Operating margin was -19.9% in FY2025, an improvement from -99.7% in FY2024 and -94.5% in FY2021. Net loss for FY2025 was -$245.0M, or -$0.61 per share, compared to -$705.8M in FY2024. In the latest quarter ended June 30, 2026, quarterly revenue increased 21.6% year-over-year, while trailing twelve-month revenue reached $1.43B with a net profit margin of -17.8% and EPS of -$1.44.

TEM income statement →

Balance sheet and cash flow

As of June 30, 2026, Tempus AI held $816.0M in cash and short-term investments against total debt of $1.44B, resulting in net debt of $628.2M. Total assets stood at $2.37B and shareholders' equity was $444.9M. The company reported a current ratio of 3.30 and a debt-to-equity ratio of 3.25. For FY2025, operating cash flow was -$218.1M and free cash flow was -$245.4M. Capital expenditures totaled $27.3M, while share buybacks were $3.0M.

TEM balance sheet →

Valuation and performance

Tempus AI carries a market capitalization of $11.68B and an enterprise value of $14.53B. The stock trades at a price-to-sales ratio of 8.2x, which is above the 4.1x median of its US-listed Healthcare peers. Its EV-to-revenue multiple is 10.1x, and its price-to-book ratio is 31.3x. Over the past year, TEM shares declined 28.9%, trailing the S&P 500 (SPY) return of 16.8%. Year to date, the stock has gained 9.6% and trades 14.0% above its 200-day moving average.

TEM key metrics →

What analysts expect

Wall Street analysts hold 8 Strong Buy, 2 Buy, 9 Hold, 0 Sell, and 1 Strong Sell ratings on TEM. The mean price target is $74.94, representing a 15.8% upside relative to the last close of $64.72. For the fiscal year ending December 31, 2026, consensus estimates project an EPS of -$0.25 on revenue of $1.60B. For the next fiscal year, 14 analysts project revenue of $1.97B and an EPS of -$0.05. Tempus AI has beaten EPS estimates in each of the last 4 quarters, with its next earnings release scheduled for November 3, 2026.

TEM forecast and price target →

Key risks and what to watch

  • Ongoing negative cash flow of -$218.1M in FY2025 operating cash flow could pressure the $816.0M cash balance if profitability is delayed.
  • Stock price volatility is elevated, as reflected by a high beta of 3.54 and a 24.9% short interest as a percentage of float.
  • Shareholders' equity of $444.9M is low relative to $1.44B in total debt, creating potential balance sheet vulnerability.

AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer

About this TEM AI stock analysis

This page is an AI-written research summary of Tempus AI, Inc. (TEM). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.

Related: TEM income statement, TEM balance sheet, TEM key metrics, TEM analyst forecast, TEM chart. See the TEM stock overview for the latest quote and news.

TEM AI stock analysis FAQ

Does Tempus AI pay a dividend?

No, Tempus AI does not pay a dividend. The company directs its capital toward business operations, research and development, and growth initiatives.

What is Tempus AI's revenue growth profile?

Tempus AI expanded its revenue by 83.4% to $1.27B in FY2025, posting a 5-year compound annual growth rate of 46.6% from FY2020 through FY2025. In the quarter ended June 30, 2026, year-over-year revenue growth was 21.6%.

Is Tempus AI profitable?

No, Tempus AI is not currently profitable. In FY2025, the company posted a net loss of -$245.0M with a net margin of -19.3%, and trailing twelve-month net margin stands at -17.8%.

What do analysts project for Tempus AI's stock price and earnings?

Analysts have an average price target of $74.94, which is 15.8% above its last close of $64.72. Consensus estimates expect EPS of -$0.25 on revenue of $1.60B for the fiscal year ending December 31, 2026.

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