Twist Bioscience Corporation (TWST) Ownership
TWST ownership summary
as of October 18, 2026- Institutions
- 117.2% of shares outstanding
- Insiders
- 0.91% of shares outstanding
- Shares outstanding
- 66.3M
- Float
- 61.9M shares available to trade
- Short interest
- 20.10% 10.6M shares short
- Days to cover
- 4.94 short interest down 15.5% vs prior month
- Institutions 117.21%
- Insiders 0.91%
TWST top institutional holders
20 largest| # | Holder | % of shares | Shares | Value | Change | Reported |
|---|---|---|---|---|---|---|
| 1 | BlackRock Inc | 8.80% | 5.8M | $774.4M | +279,529 (+5.0%) | June 30, 2026 |
| 2 | Artisan Partners Limited Partnership | 7.24% | 4.8M | $637.5M | −1.6M (−24.6%) | June 30, 2026 |
| 3 | FMR Inc | 7.09% | 4.7M | $624.3M | +2.8M (+148.8%) | June 30, 2026 |
| 4 | ARK Investment Management LLC | 6.86% | 4.5M | $604.0M | −1.8M (−28.3%) | June 30, 2026 |
| 5 | T. Rowe Price Associates, Inc. | 5.48% | 3.6M | $482.5M | +3.6M (+5,069.8%) | June 30, 2026 |
| 6 | State Street Corp | 4.88% | 3.2M | $429.1M | −438,150 (−11.9%) | June 30, 2026 |
| 7 | Vanguard Portfolio Management, LLC | 4.26% | 2.8M | $375.0M | +175,888 (+6.6%) | June 30, 2026 |
| 8 | Vanguard Capital Management, LLC | 4.07% | 2.7M | $358.3M | +60,236 (+2.3%) | June 30, 2026 |
| 9 | EdgePoint Investment | 3.80% | 2.5M | $334.7M | −2.9M (−53.2%) | June 30, 2026 |
| 10 | William Blair Investment Management, LLC | 3.28% | 2.2M | $288.7M | −3.1M (−58.7%) | June 30, 2026 |
| 11 | Farallon Capital Management, L.L.C. | 3.22% | 2.1M | $283.6M | +708,750 (+49.6%) | June 30, 2026 |
| 12 | Amvescap Plc. | 2.91% | 1.9M | $256.0M | −243,669 (−11.2%) | June 30, 2026 |
| 13 | Geode Capital Management, LLC | 2.44% | 1.6M | $215.0M | +99,648 (+6.6%) | June 30, 2026 |
| 14 | Thrivent Financial For Lutherans | 2.16% | 1.4M | $190.3M | +120,959 (+9.2%) | June 30, 2026 |
| 15 | The Goldman Sachs Group Inc | 2.12% | 1.4M | $187.0M | −297,128 (−17.4%) | June 30, 2026 |
| 16 | Morgan Stanley - Brokerage Accounts | 1.79% | 1.2M | $158.0M | +643,016 (+117.6%) | June 30, 2026 |
| 17 | D. E. Shaw & Co LP | 1.79% | 1.2M | $157.4M | +1.1M (+2,441.8%) | June 30, 2026 |
| 18 | Baillie Gifford & Co Limited. | 1.64% | 1.1M | $144.3M | −128,372 (−10.6%) | June 30, 2026 |
| 19 | Driehaus Capital Management LLC | 1.54% | 1.0M | $135.7M | +437,830 (+74.9%) | June 30, 2026 |
| 20 | Sumitomo Mitsui Trust Group Inc | 1.51% | 1.0M | $132.8M | −495,755 (−33.1%) | June 30, 2026 |
Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 11 holders added 10.0M shares and 9 cut 10.9M.
TWST top mutual fund and ETF holders
20 largest| # | Holder | % of shares | Shares | Value | Change | Reported |
|---|---|---|---|---|---|---|
| 1 | EdgePoint Global Portfolio Series F | 4.24% | 2.8M | $373.0M | — | March 31, 2026 |
| 2 | Vanguard MStar Total Stk Mkt Idx Invest | 3.00% | 2.0M | $264.1M | +108,458 (+5.8%) | August 31, 2026 |
| 3 | ARK Innovation ETF | 2.71% | 1.8M | $238.2M | −190,935 (−9.6%) | September 30, 2026 |
| 4 | iShares Russell 2000 ETF | 2.59% | 1.7M | $227.6M | −19,776 (−1.1%) | September 30, 2026 |
| 5 | Vanguard Small Cap Index | 2.25% | 1.5M | $198.0M | +52,601 (+3.7%) | September 30, 2026 |
| 6 | EdgePoint Global Growth & Inc Port Sr F | 2.02% | 1.3M | $177.6M | — | March 31, 2026 |
| 7 | Fidelity Global Innovators Cl F | 1.95% | 1.3M | $171.5M | +1.3M (0.0%) | June 30, 2026 |
| 8 | State Street® SPDR® S&P® Biotech ETF | 1.79% | 1.2M | $157.3M | −22,550 (−1.9%) | September 30, 2026 |
| 9 | ARK Genomic Revolution ETF | 1.79% | 1.2M | $157.2M | +2,894 (+0.2%) | September 30, 2026 |
| 10 | T. Rowe Price New Horizons | 1.25% | 831K | $110.3M | −136,214 (−14.1%) | September 30, 2026 |
| 11 | Vanguard MStar Small Cap Growth Indx Inv | 1.25% | 831K | $110.3M | +4,816 (+0.6%) | September 30, 2026 |
| 12 | Invesco Discovery A | 1.14% | 755K | $100.2M | −106,897 (−12.4%) | August 31, 2026 |
| 13 | Fidelity Small Cap Index | 1.02% | 679K | $90.1M | +5,776 (+0.9%) | July 31, 2026 |
| 14 | iShares Russell 2000 Growth ETF | 0.93% | 619K | $82.2M | −784 (−0.1%) | September 30, 2026 |
| 15 | Fidelity Blue Chip Growth | 0.86% | 572K | $76.0M | +572,300 (0.0%) | August 31, 2026 |
| 16 | Vanguard Explorer Inv | 0.84% | 554K | $73.6M | +554,455 (0.0%) | June 30, 2026 |
| 17 | Edinburgh Worldwide Ord | 0.76% | 505K | $67.0M | — | June 30, 2026 |
| 18 | iShares Biotechnology ETF | 0.75% | 497K | $66.0M | −3,768 (−0.8%) | September 30, 2026 |
| 19 | Fidelity Select Biotechnology | 0.71% | 469K | $62.2M | +177,909 (+61.2%) | August 31, 2026 |
| 20 | T. Rowe Price Health Sciences | 0.68% | 453K | $60.2M | — | September 30, 2026 |
Funds report holdings monthly or quarterly; dates differ by fund.
TWST insider transactions
latest 20| Date | Name | Transaction | Price | Shares | Value |
|---|---|---|---|---|---|
| 2026-04-22 | Emily M Leproust | Sell | $65.29 | 8,061 | $526,303 |
| 2026-04-21 | Emily M Leproust | Sell | $65.01 | 1,610 | $104,666 |
| 2026-04-17 | Adam Laponis | Sell | $60.00 | 4,000 | $240,000 |
| 2026-04-14 | Adam Laponis | Sell | $55.00 | 3,000 | $165,000 |
| 2026-04-09 | Adam Laponis | Sell | $49.89 | 2,597 | $129,564 |
| 2026-04-01 | Melissa A Starovasnik | Sell | $51.00 | 1,000 | $51,000 |
| 2026-03-17 | Robert Chess | Sell | $47.00 | 10,000 | $470,000 |
| 2026-03-06 | Dennis Cho | Sell | $46.43 | 425 | $19,733 |
| 2026-03-06 | Emily M Leproust | Sell | $46.43 | 2,423 | $112,500 |
| 2026-03-06 | Paula Green | Sell | $46.43 | 935 | $43,412 |
| 2026-02-12 | Adam Laponis | Sell | $50.00 | 7,000 | $350,000 |
| 2026-02-11 | Dennis Cho | Sell | $49.93 | 5,000 | $249,650 |
| 2026-02-06 | Jan Johannessen | Sell | $47.91 | 2,200 | $105,402 |
| 2026-02-04 | Robert F Werner | Sell | $45.65 | 7,000 | $319,550 |
| 2026-02-03 | Dennis Cho | Sell | $46.58 | 1,099 | $51,191 |
| 2026-02-03 | Emily M Leproust | Sell | $46.58 | 5,001 | $232,947 |
| 2026-02-03 | Paula Green | Sell | $46.58 | 1,194 | $55,617 |
| 2026-02-03 | Robert F Werner | Sell | $46.58 | 175 | $8,152 |
| 2026-01-13 | Adam Laponis | Sell | $40.00 | 3,000 | $120,000 |
| 2026-01-09 | Adam Laponis | Sell | $35.26 | 2,738 | $96,542 |
Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.
TWST shares outstanding
Year-end shares outstanding, adjusted for splits.
Who owns TWST
Institutional investors own 117.2% of Twist Bioscience's shares and insiders 0.91%. The largest holder is BlackRock Inc with 8.80% of the shares (5.8M), as of June 30, 2026. Among the top 20 institutions, 11 added shares and 9 reduced their stake in the latest filings. Short interest is 20.10% of the float, or 4.94 days of average trading volume. The share count rose 2,954.0% since 2016.
Related: TWST analyst forecast, TWST key metrics. See the TWST stock overview for the latest quote and news.
TWST ownership FAQ
Who owns the most Twist Bioscience stock?
The largest shareholders of Twist Bioscience are BlackRock Inc (8.80%), Artisan Partners Limited Partnership (7.24%), FMR Inc (7.09%), ARK Investment Management LLC (6.86%), T. Rowe Price Associates, Inc. (5.48%).
What percentage of Twist Bioscience is owned by institutions?
Institutions hold 117.2% of Twist Bioscience's shares outstanding; insiders hold 0.91%.
Which funds own Twist Bioscience?
The largest fund holders of Twist Bioscience are EdgePoint Global Portfolio Series F (4.24%), Vanguard MStar Total Stk Mkt Idx Invest (3.00%), ARK Innovation ETF (2.71%), iShares Russell 2000 ETF (2.59%), Vanguard Small Cap Index (2.25%).
What is Twist Bioscience's short interest?
10.6M shares of Twist Bioscience were sold short, 20.10% of the float; at the average daily volume it would take 4.94 days to cover.
Are insiders buying or selling Twist Bioscience?
Of the latest 20 reported insider transactions in Twist Bioscience (since January 9, 2026), 0 were purchases and 20 were sales.
How many shares of Twist Bioscience are outstanding?
Twist Bioscience has 66.3M shares outstanding, of which 61.9M are in the public float.