Tango Therapeutics, Inc. (TNGX) Ownership

NASDAQ: TNGXTop holders, insider trades and short interest.

TNGX ownership summary

as of October 18, 2026
Institutions
128.7%
of shares outstanding
Insiders
1.19%
of shares outstanding
Shares outstanding
168.6M
Float
120.7M
shares available to trade
Short interest
26.69%
44.5M shares short
Days to cover
15.15
short interest up 6.3% vs prior month
  • Institutions 128.75%
  • Insiders 1.19%

TNGX top institutional holders

20 largest
Tango Therapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1RTW INVESTMENTS, LLC8.24%13.9M$306.4M+600,000 (+4.5%)June 30, 2026
2BlackRock Inc7.38%12.4M$274.1M+3.7M (+42.2%)June 30, 2026
3FMR Inc7.31%12.3M$271.8M+2.4M (+24.5%)June 30, 2026
4Farallon Capital Management, L.L.C.7.28%12.3M$270.6M+3.2M (+35.0%)June 30, 2026
5Boxer Capital Management, LLC6.45%10.9M$239.7M—June 30, 2026
6The Goldman Sachs Group Inc5.92%10.0M$220.0M+4.9M (+96.6%)June 30, 2026
7TCG Crossover Management, LLC5.39%9.1M$200.1M−1.4M (−13.8%)June 30, 2026
8TRV GP IV, LLC3.78%6.4M$140.5M—June 30, 2026
9Paradigm Biocapital Advisors LP3.77%6.4M$140.1M+2.3M (+58.6%)June 30, 2026
10T. Rowe Price Associates, Inc.3.77%6.3M$139.9M+5.5M (+613.8%)June 30, 2026
11Siren, L.L.C.3.66%6.2M$136.2M+522,259 (+9.2%)June 30, 2026
12State Street Corp3.55%6.0M$131.8M+1.3M (+28.5%)June 30, 2026
13Vanguard Capital Management, LLC3.53%6.0M$131.3M+795,917 (+15.4%)June 30, 2026
14Adage Capital Partners Gp LLC3.32%5.6M$123.4M−7.2M (−56.3%)June 30, 2026
15Jupiter Topco LLC3.00%5.1M$111.4M+5.1M (0.0%)June 30, 2026
16Deep Track Capital, LP2.49%4.2M$92.6M+1.4M (+52.7%)June 30, 2026
17Deerfield Management Co2.49%4.2M$92.4M+43,798 (+1.1%)June 30, 2026
18Woodline Partners LP2.37%4.0M$88.2M−4.0M (−50.0%)June 30, 2026
19Geode Capital Management, LLC2.22%3.7M$82.5M+1.1M (+39.9%)June 30, 2026
20Perceptive Advisors LLC2.00%3.4M$74.4M+2.6M (+317.9%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 15 holders added 35.4M shares and 3 cut 12.7M.

TNGX top mutual fund and ETF holders

20 largest
Tango Therapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.61%4.4M$97.1M−5,262 (−0.1%)August 31, 2026
2State Street® SPDR® S&P® Biotech ETF2.43%4.1M$90.2M−77,900 (−1.9%)September 30, 2026
3iShares Russell 2000 ETF2.16%3.6M$80.4M−42,048 (−1.1%)September 30, 2026
4Fidelity Growth Company Fund1.67%2.8M$61.9M+63,800 (+2.3%)August 31, 2026
5Fidelity Select Biotechnology1.48%2.5M$55.1M+76,100 (+3.1%)August 31, 2026
6Fidelity Small Cap Index0.91%1.5M$33.9M+12,850 (+0.8%)July 31, 2026
7T. Rowe Price New Horizons0.84%1.4M$31.0M−57,531 (−3.9%)August 31, 2026
8Polar Capital Biotech S Inc0.83%1.4M$30.9M—August 31, 2026
9iShares Russell 2000 Growth ETF0.78%1.3M$29.0M−1,668 (−0.1%)September 30, 2026
10T. Rowe Price Integrated US Sm Gr Eq0.71%1.2M$26.5M—August 31, 2026
11iShares Biotechnology ETF0.64%1.1M$24.0M−8,240 (−0.8%)September 30, 2026
12Franklin Biotechnology Discv A(acc)USD0.57%965K$21.3M—August 31, 2026
13Lord Abbett Developing Growth A0.50%851K$18.8M+473,318 (+125.3%)July 31, 2026
14Belfius Equities Cure C Cap0.49%823K$18.1M+165,030 (+25.1%)March 31, 2026
15Vanguard Russell 2000 ETF0.48%810K$17.8M+19,168 (+2.4%)August 31, 2026
16Janus Henderson Hrzn Biotec E2 USD0.48%808K$17.8M+407,391 (+101.6%)June 30, 2026
17American Century Small Cap Growth Inv0.46%773K$17.0M+773,207 (0.0%)June 30, 2026
18Schwab US Small-Cap ETF™0.45%763K$16.8M+513 (+0.1%)September 30, 2026
19Fidelity Series Growth Company0.45%750K$16.5M+13,600 (+1.8%)August 31, 2026
20Fidelity Growth Company K60.44%735K$16.2M+36,000 (+5.1%)August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

TNGX insider transactions

latest 15
Tango Therapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-04-15Adam CrystalSell$25.0038,460$961,500
2026-04-01Adam CrystalSell$21.2027,000$572,400
2026-03-25Adam CrystalSell$20.1112,000$241,320
2026-03-05Adam CrystalSell$15.0020,251$303,765
2026-02-25Adam CrystalSell$12.7754,345$693,986
2026-02-03Adam CrystalSell$12.2618,452$226,222
2026-02-03Barbara WeberSell$12.2630,519$374,163
2026-02-03Daniella BeckmanSell$12.2610,317$126,486
2025-10-23Rock Ventures Iv L.P. ThirdSell$10.15477,401$4.8M
2025-09-25Rock Ventures Iv L.P. ThirdSell$8.02500,000$4.0M
2025-09-16Rock Ventures Iv L.P. ThirdSell$7.04363,541$2.6M
2025-09-08Rock Ventures Iv L.P. ThirdSell$7.0486,459$608,671
2025-09-05Rock Ventures Iv L.P. ThirdSell$7.00642,906$4.5M
2025-08-22Rock Ventures Iv L.P. ThirdSell$7.00302,194$2.1M
2025-08-19Rock Ventures Iv L.P. ThirdSell$7.011,100,000$7.7M

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

TNGX shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns TNGX

Institutional investors own 128.7% of Tango Therapeutics's shares and insiders 1.19%. The largest holder is RTW INVESTMENTS, LLC with 8.24% of the shares (13.9M), as of June 30, 2026. Among the top 20 institutions, 15 added shares and 3 reduced their stake in the latest filings. Short interest is 26.69% of the float, or 15.15 days of average trading volume. The share count rose 32.8% since 2020.

Related: TNGX analyst forecast, TNGX key metrics. See the TNGX stock overview for the latest quote and news.

TNGX ownership FAQ

Who owns the most Tango Therapeutics stock?

The largest shareholders of Tango Therapeutics are RTW INVESTMENTS, LLC (8.24%), BlackRock Inc (7.38%), FMR Inc (7.31%), Farallon Capital Management, L.L.C. (7.28%), Boxer Capital Management, LLC (6.45%).

What percentage of Tango Therapeutics is owned by institutions?

Institutions hold 128.7% of Tango Therapeutics's shares outstanding; insiders hold 1.19%.

Which funds own Tango Therapeutics?

The largest fund holders of Tango Therapeutics are Vanguard MStar Total Stk Mkt Idx Invest (2.61%), State Street® SPDR® S&P® Biotech ETF (2.43%), iShares Russell 2000 ETF (2.16%), Fidelity Growth Company Fund (1.67%), Fidelity Select Biotechnology (1.48%).

What is Tango Therapeutics's short interest?

44.5M shares of Tango Therapeutics were sold short, 26.69% of the float; at the average daily volume it would take 15.15 days to cover.

Are insiders buying or selling Tango Therapeutics?

Of the latest 15 reported insider transactions in Tango Therapeutics (since August 19, 2025), 0 were purchases and 15 were sales.

How many shares of Tango Therapeutics are outstanding?

Tango Therapeutics has 168.6M shares outstanding, of which 120.7M are in the public float.

Biotechnology: ownership