Polaryx Therapeutics, Inc. (PLYX) Ownership

NASDAQ: PLYXTop holders, insider trades and short interest.

PLYX ownership summary

as of October 18, 2026
Institutions
4.4%
of shares outstanding
Insiders
69.92%
of shares outstanding
Shares outstanding
49.8M
Float
7.2M
shares available to trade
Short interest
0.67%
143K shares short
Days to cover
4.57
short interest down 23.3% vs prior month
  • Institutions 4.40%
  • Insiders 69.92%
  • Other investors 25.68%

PLYX top institutional holders

18 largest
Polaryx Therapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1Vanguard Capital Management, LLC3.33%1.7M$3.1M−516 (−0.0%)June 30, 2026
2Geode Capital Management, LLC0.34%171K$321,476+325 (+0.2%)June 30, 2026
3Vanguard Fiduciary Trust Co0.21%105K$197,535+516 (+0.5%)June 30, 2026
4HRT FINANCIAL LLC0.16%82K$154,337+82,094 (0.0%)June 30, 2026
5State Street Corp0.12%58K$109,236—June 30, 2026
6BlackRock Inc0.08%41K$77,103—June 30, 2026
7Jane Street Group LLC0.06%31K$59,109+31,441 (0.0%)June 30, 2026
8Northern Trust Corp0.06%28K$52,616—June 30, 2026
9Hanson Mcclain Inc0.02%7,727$14,527+7,727 (0.0%)June 30, 2026
10Vanguard Global Advisers, LLC0.01%6,318$11,878—June 30, 2026
11Tower Research Capital LLC0.01%3,002$5,644+1,221 (+68.6%)June 30, 2026
12UBS Group AG<0.01%1,283$2,412−12,196 (−90.5%)June 30, 2026
13Fortitude Family Office LLC<0.01%189$355+189 (0.0%)June 30, 2026
14The Goldman Sachs Group Inc0.00%——−13,483 (−100.0%)June 30, 2026
15Millennium Management LLC0.00%——−127,525 (−100.0%)June 30, 2026
16Morgan Stanley - Brokerage Accounts0.00%——−5,543 (−100.0%)June 30, 2026
17Squarepoint Ops LLC0.00%——−12,406 (−100.0%)June 30, 2026
18Bank of America Corp0.00%——−25,881 (−100.0%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 18, 7 holders added 124K shares and 7 cut 198K.

PLYX top mutual fund and ETF holders

8 largest
Polaryx Therapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.95%1.5M$2.8M—August 31, 2026
2Fidelity Extended Market Index0.13%65K$122,426−350 (−0.5%)August 31, 2026
3Fidelity Total Market Index0.05%26K$49,726—August 31, 2026
4Vanguard Balanced Index Inv0.05%26K$48,822—August 31, 2026
5Vanguard MStar Inst Ttl StkMktIdxInstlPl0.04%22K$41,089—August 31, 2026
6Fidelity Series Total Market Index0.04%20K$36,857—August 31, 2026
7Fidelity Nasdaq Composite Index0.04%19K$35,799−9,606 (−33.5%)August 31, 2026
8Vanguard U.S. Eq Idx £ Acc0.01%6,318$11,878—August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

PLYX insider transactions

latest 1
Polaryx Therapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-02-18G. Michael LandisBuy$2.792,867$7,999

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

Who owns PLYX

Institutional investors own 4.4% of Polaryx Therapeutics's shares and insiders 69.92%. The largest holder is Vanguard Capital Management, LLC with 3.33% of the shares (1.7M), as of June 30, 2026. Among the top 18 institutions, 7 added shares and 7 reduced their stake in the latest filings. Short interest is 0.67% of the float, or 4.57 days of average trading volume. The share count fell 75.0% since 2024.

Related: PLYX analyst forecast, PLYX key metrics. See the PLYX stock overview for the latest quote and news.

PLYX ownership FAQ

Who owns the most Polaryx Therapeutics stock?

The largest shareholders of Polaryx Therapeutics are Vanguard Capital Management, LLC (3.33%), Geode Capital Management, LLC (0.34%), Vanguard Fiduciary Trust Co (0.21%), HRT FINANCIAL LLC (0.16%), State Street Corp (0.12%).

What percentage of Polaryx Therapeutics is owned by institutions?

Institutions hold 4.4% of Polaryx Therapeutics's shares outstanding; insiders hold 69.92%.

Which funds own Polaryx Therapeutics?

The largest fund holders of Polaryx Therapeutics are Vanguard MStar Total Stk Mkt Idx Invest (2.95%), Fidelity Extended Market Index (0.13%), Fidelity Total Market Index (0.05%), Vanguard Balanced Index Inv (0.05%), Vanguard MStar Inst Ttl StkMktIdxInstlPl (0.04%).

What is Polaryx Therapeutics's short interest?

143K shares of Polaryx Therapeutics were sold short, 0.67% of the float; at the average daily volume it would take 4.57 days to cover.

Are insiders buying or selling Polaryx Therapeutics?

Of the latest 1 reported insider transactions in Polaryx Therapeutics (since February 18, 2026), 1 were purchases and 0 were sales.

How many shares of Polaryx Therapeutics are outstanding?

Polaryx Therapeutics has 49.8M shares outstanding, of which 7.2M are in the public float.

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