Oruka Therapeutics, Inc. (ORKA) Ownership

NASDAQ: ORKATop holders, insider trades and short interest.

ORKA ownership summary

as of October 18, 2026
Institutions
116.6%
of shares outstanding
Insiders
1.25%
of shares outstanding
Shares outstanding
66.2M
Float
56.9M
shares available to trade
Short interest
17.10%
7.8M shares short
Days to cover
7.87
short interest up 2.0% vs prior month
  • Institutions 116.60%
  • Insiders 1.25%

ORKA top institutional holders

20 largest
Oruka Therapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1FMR Inc13.68%9.1M$651.5M+1.6M (+21.9%)June 30, 2026
2BlackRock Inc7.54%5.0M$358.9M+1.5M (+41.5%)June 30, 2026
3VR Adviser, LLC6.27%4.1M$298.4M—June 30, 2026
4Fairmount Funds Management LLC5.60%3.7M$266.5M—June 30, 2026
5Capital World Investors5.14%3.4M$244.7M+3.4M (0.0%)June 30, 2026
6RTW INVESTMENTS, LLC4.74%3.1M$225.8M+1.1M (+52.5%)June 30, 2026
7State Street Corp4.04%2.7M$192.3M+1.1M (+65.7%)June 30, 2026
8Vanguard Capital Management, LLC3.57%2.4M$169.8M+501,340 (+27.0%)June 30, 2026
9Paradigm Biocapital Advisors LP3.24%2.1M$154.3M−175,790 (−7.6%)June 30, 2026
10Deep Track Capital, LP2.91%1.9M$138.5M−108,203 (−5.3%)June 30, 2026
11Bellevue Group AG2.50%1.7M$119.2M+1.2M (+226.9%)June 30, 2026
12Franklin Templeton Inc2.45%1.6M$116.6M+617,395 (+61.5%)June 30, 2026
13Remedium Capital Partners, LLC2.36%1.6M$112.6M—June 30, 2026
14RA Capital Management, LLC2.35%1.6M$111.8M+1.6M (0.0%)June 30, 2026
15Viking Global Investors LP2.27%1.5M$108.1M−1.2M (−43.6%)June 30, 2026
16Geode Capital Management, LLC2.16%1.4M$102.9M+475,087 (+49.8%)June 30, 2026
17Jupiter Topco LLC2.08%1.4M$99.0M+1.4M (0.0%)June 30, 2026
18Perceptive Advisors LLC2.03%1.3M$96.8M−50,438 (−3.6%)June 30, 2026
19Polar Capital Holdings PLC1.86%1.2M$88.4M+180,916 (+17.3%)June 30, 2026
20Citadel Advisors Llc1.69%1.1M$80.5M+111,474 (+11.1%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 13 holders added 14.6M shares and 4 cut 1.5M.

ORKA top mutual fund and ETF holders

20 largest
Oruka Therapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.61%1.7M$124.3M−2,176 (−0.1%)August 31, 2026
2State Street® SPDR® S&P® Biotech ETF2.46%1.6M$116.9M−30,950 (−1.9%)September 30, 2026
3American Funds SMALLCAP World A2.31%1.5M$109.9M+1.5M (0.0%)June 30, 2026
4American Funds New Economy A2.00%1.3M$95.2M+1.3M (0.0%)June 30, 2026
5iShares Russell 2000 ETF1.97%1.3M$93.9M−15,040 (−1.1%)September 30, 2026
6Fidelity Growth Company Fund1.95%1.3M$93.1M—August 31, 2026
7Polar Capital Biotech S Inc1.76%1.2M$83.7M—August 31, 2026
8Fidelity Select Health Care1.33%880K$63.3M+15,000 (+1.7%)August 31, 2026
9Fidelity Advisor Biotechnology I1.11%737K$53.0M—August 31, 2026
10Fidelity Small Cap Growth1.04%686K$49.3M—July 31, 2026
11Fidelity Select Biotechnology0.85%563K$40.5M—August 31, 2026
12Fidelity Small Cap Index0.83%551K$39.6M+4,639 (+0.8%)July 31, 2026
13Franklin Biotechnology Discv A(acc)USD0.83%548K$39.4M—August 31, 2026
14iShares Russell 2000 Growth ETF0.71%471K$33.9M−597 (−0.1%)September 30, 2026
15iShares Biotechnology ETF0.69%459K$33.0M−3,480 (−0.8%)September 30, 2026
16Fidelity Advisor Health Care I0.65%428K$30.8M—August 31, 2026
17Candriam Eqs L Biotech C USD Cap0.60%401K$28.8M—March 31, 2026
18RTW Biotech Opportunities Ord0.58%386K$27.7M+385,571 (0.0%)December 31, 2025
19Fidelity Growth Company K60.57%379K$27.2M—August 31, 2026
20Pictet-Biotech P USD0.56%374K$26.9M−1,516 (−0.4%)June 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

ORKA insider transactions

latest 7
Oruka Therapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-04-15Joana GoncalvesSell$66.127,000$462,840
2026-03-16Arjun AgarwalSell$41.30395$16,313
2026-03-16Joana GoncalvesSell$40.917,641$312,593
2026-03-16Lawrence Otto KleinSell$41.301,729$71,408
2026-02-17Joana GoncalvesSell$32.377,000$226,590
2026-01-15Joana GoncalvesSell$31.817,000$222,670
2025-12-19Joana GoncalvesSell$30.617,000$214,270

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

ORKA shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns ORKA

Institutional investors own 116.6% of Oruka Therapeutics's shares and insiders 1.25%. The largest holder is FMR Inc with 13.68% of the shares (9.1M), as of June 30, 2026. Among the top 20 institutions, 13 added shares and 4 reduced their stake in the latest filings. Short interest is 17.10% of the float, or 7.87 days of average trading volume. The share count rose 99,753.2% since 2017.

Related: ORKA analyst forecast, ORKA key metrics. See the ORKA stock overview for the latest quote and news.

ORKA ownership FAQ

Who owns the most Oruka Therapeutics stock?

The largest shareholders of Oruka Therapeutics are FMR Inc (13.68%), BlackRock Inc (7.54%), VR Adviser, LLC (6.27%), Fairmount Funds Management LLC (5.60%), Capital World Investors (5.14%).

What percentage of Oruka Therapeutics is owned by institutions?

Institutions hold 116.6% of Oruka Therapeutics's shares outstanding; insiders hold 1.25%.

Which funds own Oruka Therapeutics?

The largest fund holders of Oruka Therapeutics are Vanguard MStar Total Stk Mkt Idx Invest (2.61%), State Street® SPDR® S&P® Biotech ETF (2.46%), American Funds SMALLCAP World A (2.31%), American Funds New Economy A (2.00%), iShares Russell 2000 ETF (1.97%).

What is Oruka Therapeutics's short interest?

7.8M shares of Oruka Therapeutics were sold short, 17.10% of the float; at the average daily volume it would take 7.87 days to cover.

Are insiders buying or selling Oruka Therapeutics?

Of the latest 7 reported insider transactions in Oruka Therapeutics (since December 19, 2025), 0 were purchases and 7 were sales.

How many shares of Oruka Therapeutics are outstanding?

Oruka Therapeutics has 66.2M shares outstanding, of which 56.9M are in the public float.

Biotechnology: ownership