Milestone Pharmaceuticals Inc. (MIST) Ownership

NASDAQ: MISTTop holders, insider trades and short interest.

MIST ownership summary

as of October 18, 2026
Institutions
51.5%
of shares outstanding
Insiders
0.70%
of shares outstanding
Shares outstanding
124.5M
Float
106.5M
shares available to trade
Short interest
15.38%
19.0M shares short
Days to cover
13.18
short interest up 3.5% vs prior month
  • Institutions 51.50%
  • Insiders 0.70%
  • Other investors 47.80%

MIST top institutional holders

20 largest
Milestone Pharmaceuticals Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1Pavaki Capital Management LLC7.28%9.1M$6.4M+5,000 (+0.1%)June 30, 2026
2RTW INVESTMENTS, LLC6.29%7.8M$5.5M+1.5M (+23.7%)June 30, 2026
3Propel Bio Management LLC5.97%7.4M$5.3M+3.3M (+80.4%)June 30, 2026
4Point72 Asset Management, L.P.4.35%5.4M$3.8M+4.3M (+398.4%)June 30, 2026
5Simplify Asset Management Inc.2.69%3.3M$2.4M+1.8M (+122.3%)June 30, 2026
6Millennium Management LLC2.52%3.1M$2.2M+1.6M (+103.5%)June 30, 2026
7Kalehua Capital Management LLC2.04%2.5M$1.8M+2.5M (0.0%)June 30, 2026
8Two Sigma Investments LLC1.64%2.0M$1.4M−277,161 (−12.0%)June 30, 2026
9Marshall Wace Asset Management Ltd1.44%1.8M$1.3M−146,835 (−7.6%)June 30, 2026
10Lion Point Capital, LP0.66%820K$579,740—June 30, 2026
11The Toronto-Dominion Bank0.60%750K$530,250—June 30, 2026
12Ameriprise Financial Inc0.54%667K$471,333+666,666 (0.0%)June 30, 2026
13Boxer Capital Management, LLC0.54%667K$471,333—June 30, 2026
14Morgan Stanley - Brokerage Accounts0.51%635K$449,094−88,930 (−12.3%)June 30, 2026
15UBS Group AG0.37%465K$329,040−29,505 (−6.0%)June 30, 2026
16BOOTHBAY FUND MANAGEMENT, LLC0.37%463K$327,107+293,994 (+174.3%)June 30, 2026
17Susquehanna International Group, LLP0.29%360K$254,446−159,151 (−30.7%)June 30, 2026
18Aptus Capital Advisors, LLC0.27%339K$239,991+59,200 (+21.1%)June 30, 2026
19GUARDIAN WEALTH ADVISORS, LLC / NC0.27%339K$239,991+59,200 (+21.1%)June 30, 2026
20Seven Fleet Capital Management LP0.22%270K$191,055−63,100 (−18.9%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 11 holders added 16.2M shares and 6 cut 765K.

MIST top mutual fund and ETF holders

2 largest
Milestone Pharmaceuticals Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Simplify Propel Opportunities ETF2.69%3.3M$2.4M—September 30, 2026
2State Street® SPDR® S&P® Intl Sm Cp ETF0.02%27K$19,257—September 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

MIST insider transactions

latest 11
Milestone Pharmaceuticals Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-04-16Joseph OlivetoSell$2.2636,500$82,490
2026-01-26David BharuchaSell$1.9312,245$23,633
2026-01-26Jeffrey Edward NelsonSell$1.9312,245$23,633
2026-01-26Joseph OlivetoSell$1.9334,523$66,629
2026-01-26Lorenz MullerSell$1.9311,180$21,577
2026-01-08Joseph OlivetoSell$2.2543,000$96,750
2026-01-07Joseph OlivetoSell$2.25500$1,125
2025-12-15David BharuchaSell$2.3258,007$134,576
2025-12-15Jeffrey Edward NelsonSell$2.3258,007$134,576
2025-12-15Joseph OlivetoSell$2.32133,054$308,685
2025-12-15Lorenz MullerSell$2.3253,566$124,273

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

MIST shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns MIST

Institutional investors own 51.5% of Milestone Pharmaceuticals's shares and insiders 0.70%. The largest holder is Pavaki Capital Management LLC with 7.28% of the shares (9.1M), as of June 30, 2026. Among the top 20 institutions, 11 added shares and 6 reduced their stake in the latest filings. Short interest is 15.38% of the float, or 13.18 days of average trading volume. The share count rose 254.7% since 2018.

Related: MIST analyst forecast, MIST key metrics. See the MIST stock overview for the latest quote and news.

MIST ownership FAQ

Who owns the most Milestone Pharmaceuticals stock?

The largest shareholders of Milestone Pharmaceuticals are Pavaki Capital Management LLC (7.28%), RTW INVESTMENTS, LLC (6.29%), Propel Bio Management LLC (5.97%), Point72 Asset Management, L.P. (4.35%), Simplify Asset Management Inc. (2.69%).

What percentage of Milestone Pharmaceuticals is owned by institutions?

Institutions hold 51.5% of Milestone Pharmaceuticals's shares outstanding; insiders hold 0.70%.

Which funds own Milestone Pharmaceuticals?

The largest fund holders of Milestone Pharmaceuticals are Simplify Propel Opportunities ETF (2.69%), State Street® SPDR® S&P® Intl Sm Cp ETF (0.02%).

What is Milestone Pharmaceuticals's short interest?

19.0M shares of Milestone Pharmaceuticals were sold short, 15.38% of the float; at the average daily volume it would take 13.18 days to cover.

Are insiders buying or selling Milestone Pharmaceuticals?

Of the latest 11 reported insider transactions in Milestone Pharmaceuticals (since December 15, 2025), 0 were purchases and 11 were sales.

How many shares of Milestone Pharmaceuticals are outstanding?

Milestone Pharmaceuticals has 124.5M shares outstanding, of which 106.5M are in the public float.

Biotechnology: ownership