Seres Therapeutics, Inc. (MCRB) Ownership

NASDAQ: MCRBTop holders, insider trades and short interest.

MCRB ownership summary

as of October 18, 2026
Institutions
22.8%
of shares outstanding
Insiders
11.49%
of shares outstanding
Shares outstanding
10.0M
Float
8.7M
shares available to trade
Short interest
4.05%
314K shares short
Days to cover
5.53
short interest up 4.3% vs prior month
  • Institutions 22.84%
  • Insiders 11.49%
  • Other investors 65.67%

MCRB top institutional holders

20 largest
Seres Therapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1Flagship Ventures Management, Inc.11.51%1.2M$2.8M—June 30, 2026
2Vanguard Capital Management, LLC2.86%288K$707,929−6,367 (−2.2%)June 30, 2026
3Marshall Wace Asset Management Ltd1.71%172K$423,723+32,706 (+23.4%)June 30, 2026
4Vontobel Holding Ltd.1.22%123K$302,518−15,493 (−11.2%)June 30, 2026
5BlackRock Inc1.11%111K$273,060+8,974 (+8.8%)June 30, 2026
6Geode Capital Management, LLC0.80%80K$196,736+5,139 (+6.9%)June 30, 2026
7Susquehanna International Group, LLP0.58%58K$143,487−47,011 (−44.6%)June 30, 2026
8Vanguard Fiduciary Trust Co0.48%49K$119,765+9,042 (+22.8%)June 30, 2026
9State Street Corp0.34%34K$83,396—June 30, 2026
10Lion Point Capital, LP0.31%32K$77,662—June 30, 2026
11Charles Schwab Investment Management Inc0.31%31K$76,381−581 (−1.8%)June 30, 2026
12American Century Companies Inc0.28%28K$69,650−34,003 (−54.6%)June 30, 2026
13XTX Topco Ltd0.21%21K$51,001+20,732 (0.0%)June 30, 2026
14The Goldman Sachs Group Inc0.15%15K$37,463+15,229 (0.0%)June 30, 2026
15Northern Trust Corp0.15%15K$36,322—June 30, 2026
16Amvescap Plc.0.13%13K$31,916−1,573 (−10.8%)June 30, 2026
17Morgan Stanley - Brokerage Accounts0.12%12K$29,859−9,562 (−44.1%)June 30, 2026
18Citadel Advisors Llc0.10%11K$25,840+10,504 (0.0%)June 30, 2026
19SIMPLEX TRADING, LLC0.05%4,598$11,311+1,528 (+49.8%)June 30, 2026
20SBI Securities Co Ltd0.04%4,182$10,288+700 (+20.1%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 9 holders added 105K shares and 7 cut 115K.

MCRB top mutual fund and ETF holders

16 largest
Seres Therapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.05%206K$507,178—August 31, 2026
2Fidelity Extended Market Index0.39%40K$97,187+2,877 (+7.9%)August 31, 2026
3Abante Quant Value FI0.25%25K$60,607+11,505 (+87.6%)August 31, 2026
4iShares Micro-Cap ETF0.24%24K$59,581−167 (−0.7%)September 30, 2026
5Fidelity Total Market Index0.14%14K$34,120—August 31, 2026
6Invesco RAFI US 1500 Small-Mid ETF0.13%13K$31,778—September 30, 2026
7Fidelity Series Total Market Index0.10%10K$24,952—August 31, 2026
8Goldman Sachs Absolute Ret Trckr Instl0.10%10K$24,760+7,533 (+297.5%)June 30, 2026
9EA Bridgeway Ultra-Small Company Mkt ETF0.07%7,398$18,199—September 30, 2026
10Vanguard Balanced Index Inv0.04%4,386$10,790—August 31, 2026
11Vanguard U.S. Eq Idx £ Acc0.02%1,975$4,858—August 31, 2026
121290 VT Micro Cap K0.02%1,689$4,155—August 31, 2026
13Pacific Select Large-Cap Growth I0.01%1,430$3,518—September 30, 2026
14WisdomTree US SmallCap Earnings ETF0.01%1,274$3,134—September 30, 2026
15Avantis® U.S. Small Cap Value Instl0.01%1,176$2,893—August 31, 2026
16Avantis US Small Cap Equity ETF0.01%1,003$2,467—September 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

MCRB insider transactions

latest 3
Seres Therapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2025-11-15Eric D ShaffSell$17.30217$3,754
2025-11-15Matthew R HennSell$17.301,257$21,746
2025-11-15Thomas DesrosierSell$17.3076$1,315

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

MCRB shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns MCRB

Institutional investors own 22.8% of Seres Therapeutics's shares and insiders 11.49%. The largest holder is Flagship Ventures Management, Inc. with 11.51% of the shares (1.2M), as of June 30, 2026. Among the top 20 institutions, 9 added shares and 7 reduced their stake in the latest filings. Short interest is 4.05% of the float, or 5.53 days of average trading volume. The share count rose 422.0% since 2014.

Related: MCRB analyst forecast, MCRB key metrics. See the MCRB stock overview for the latest quote and news.

MCRB ownership FAQ

Who owns the most Seres Therapeutics stock?

The largest shareholders of Seres Therapeutics are Flagship Ventures Management, Inc. (11.51%), Vanguard Capital Management, LLC (2.86%), Marshall Wace Asset Management Ltd (1.71%), Vontobel Holding Ltd. (1.22%), BlackRock Inc (1.11%).

What percentage of Seres Therapeutics is owned by institutions?

Institutions hold 22.8% of Seres Therapeutics's shares outstanding; insiders hold 11.49%.

Which funds own Seres Therapeutics?

The largest fund holders of Seres Therapeutics are Vanguard MStar Total Stk Mkt Idx Invest (2.05%), Fidelity Extended Market Index (0.39%), Abante Quant Value FI (0.25%), iShares Micro-Cap ETF (0.24%), Fidelity Total Market Index (0.14%).

What is Seres Therapeutics's short interest?

314K shares of Seres Therapeutics were sold short, 4.05% of the float; at the average daily volume it would take 5.53 days to cover.

Are insiders buying or selling Seres Therapeutics?

Of the latest 3 reported insider transactions in Seres Therapeutics (since November 15, 2025), 0 were purchases and 3 were sales.

How many shares of Seres Therapeutics are outstanding?

Seres Therapeutics has 10.0M shares outstanding, of which 8.7M are in the public float.

Biotechnology: ownership