Krystal Biotech, Inc. (KRYS) Ownership
KRYS ownership summary
as of October 18, 2026- Institutions
- 102.4% of shares outstanding
- Insiders
- 10.66% of shares outstanding
- Shares outstanding
- 29.6M
- Float
- 23.6M shares available to trade
- Short interest
- 19.23% 3.5M shares short
- Days to cover
- 12.53 short interest up 9.9% vs prior month
- Institutions 102.40%
- Insiders 10.66%
KRYS top institutional holders
20 largest| # | Holder | % of shares | Shares | Value | Change | Reported |
|---|---|---|---|---|---|---|
| 1 | FMR Inc | 14.93% | 4.4M | $1.40B | +44,210 (+1.0%) | June 30, 2026 |
| 2 | BlackRock Inc | 14.13% | 4.2M | $1.32B | +240,976 (+6.1%) | June 30, 2026 |
| 3 | venBio Select Advisor LLC | 9.76% | 2.9M | $914.6M | — | June 30, 2026 |
| 4 | Vanguard Portfolio Management, LLC | 5.32% | 1.6M | $498.6M | +118,178 (+8.1%) | June 30, 2026 |
| 5 | State Street Corp | 4.56% | 1.4M | $427.7M | +36,724 (+2.8%) | June 30, 2026 |
| 6 | Vanguard Capital Management, LLC | 4.19% | 1.2M | $392.7M | +75,243 (+6.5%) | June 30, 2026 |
| 7 | Soleus Capital Management, L.P. | 3.17% | 939K | $297.3M | −213,833 (−18.5%) | June 30, 2026 |
| 8 | Capital World Investors | 2.63% | 778K | $246.2M | −46,877 (−5.7%) | June 30, 2026 |
| 9 | Vestor Capital Partners | 2.37% | 701K | $221.9M | +700,714 (+350,357.0%) | June 30, 2026 |
| 10 | Geode Capital Management, LLC | 2.36% | 699K | $221.3M | +55,018 (+8.5%) | June 30, 2026 |
| 11 | T. Rowe Price Associates, Inc. | 2.32% | 687K | $217.6M | +202,326 (+41.7%) | June 30, 2026 |
| 12 | Hood River Capital Management LLC | 2.24% | 663K | $210.0M | +43,789 (+7.1%) | June 30, 2026 |
| 13 | Redmile Group, LLC | 2.14% | 632K | $200.1M | −41,500 (−6.2%) | June 30, 2026 |
| 14 | William Blair Investment Management, LLC | 1.93% | 570K | $180.5M | +162,975 (+40.0%) | June 30, 2026 |
| 15 | Frazier Life Sciences Management, L.P. | 1.63% | 481K | $152.4M | — | June 30, 2026 |
| 16 | Dimensional Fund Advisors, Inc. | 1.61% | 476K | $150.7M | +7,048 (+1.5%) | June 30, 2026 |
| 17 | First Trust Advisors L.P. | 1.10% | 325K | $102.9M | −25,621 (−7.3%) | June 30, 2026 |
| 18 | Amvescap Plc. | 1.10% | 325K | $102.8M | +73,382 (+29.2%) | June 30, 2026 |
| 19 | The Goldman Sachs Group Inc | 1.01% | 299K | $94.6M | +83,892 (+39.0%) | June 30, 2026 |
| 20 | Northern Trust Corp | 0.96% | 284K | $89.8M | +31,321 (+12.4%) | June 30, 2026 |
Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 14 holders added 1.9M shares and 4 cut 328K.
KRYS top mutual fund and ETF holders
20 largest| # | Holder | % of shares | Shares | Value | Change | Reported |
|---|---|---|---|---|---|---|
| 1 | Fidelity Select Biotechnology | 6.09% | 1.8M | $570.7M | — | August 31, 2026 |
| 2 | iShares Core S&P Mid-Cap ETF | 3.21% | 949K | $300.4M | −336 (−0.0%) | September 30, 2026 |
| 3 | Vanguard MStar Total Stk Mkt Idx Invest | 3.01% | 891K | $282.2M | −1,020 (−0.1%) | August 31, 2026 |
| 4 | Fidelity Growth Company Fund | 2.76% | 816K | $258.4M | +6,634 (+0.8%) | August 31, 2026 |
| 5 | American Funds SMALLCAP World A | 2.54% | 752K | $238.1M | — | September 30, 2026 |
| 6 | iShares Russell 2000 ETF | 2.28% | 675K | $213.7M | −7,808 (−1.1%) | September 30, 2026 |
| 7 | Vanguard Small Cap Index | 2.02% | 599K | $189.7M | −45,106 (−7.0%) | September 30, 2026 |
| 8 | State Street® SPDR® S&P® Biotech ETF | 1.44% | 427K | $135.3M | −8,150 (−1.9%) | September 30, 2026 |
| 9 | Vanguard MStar Small Cap Growth Indx Inv | 1.13% | 334K | $105.7M | −35,890 (−9.7%) | September 30, 2026 |
| 10 | Hood River Small-Cap Growth Instl | 1.11% | 330K | $104.4M | — | June 30, 2026 |
| 11 | Fidelity Small Cap Index | 0.96% | 286K | $90.4M | +2,431 (+0.9%) | July 31, 2026 |
| 12 | Invesco S&P MidCap Momentum ETF | 0.91% | 268K | $84.8M | — | September 30, 2026 |
| 13 | iShares Russell 2000 Growth ETF | 0.83% | 245K | $77.5M | −310 (−0.1%) | September 30, 2026 |
| 14 | Fidelity Growth Company K6 | 0.77% | 229K | $72.3M | +200 (+0.1%) | August 31, 2026 |
| 15 | iShares Biotechnology ETF | 0.68% | 202K | $64.0M | −1,528 (−0.8%) | September 30, 2026 |
| 16 | State Street® SPDR® S&P MIDCAP 400® ETF | 0.67% | 197K | $62.4M | +5,091 (+2.7%) | September 30, 2026 |
| 17 | Fidelity Series Growth Company | 0.66% | 195K | $61.8M | +200 (+0.1%) | August 31, 2026 |
| 18 | Franklin DynaTech Fund A | 0.59% | 176K | $55.7M | +26,085 (+17.4%) | August 31, 2026 |
| 19 | iShares S&P Mid-Cap 400 Growth ETF | 0.52% | 154K | $48.7M | −164 (−0.1%) | September 30, 2026 |
| 20 | Vanguard Russell 2000 ETF | 0.51% | 152K | $48.1M | +1,706 (+1.1%) | September 30, 2026 |
Funds report holdings monthly or quarterly; dates differ by fund.
KRYS insider transactions
latest 19| Date | Name | Transaction | Price | Shares | Value |
|---|---|---|---|---|---|
| 2026-03-04 | Suma Krishnan | Sell | $263.21 | 25,000 | $6.6M |
| 2026-03-02 | Kathryn Romano | Sell | $267.60 | 750 | $200,700 |
| 2026-02-27 | Daniel Janney | Sell | $275.59 | 11,803 | $3.3M |
| 2026-02-26 | Daniel Janney | Sell | $275.63 | 7,741 | $2.1M |
| 2026-02-25 | Daniel Janney | Sell | $275.00 | 700 | $192,500 |
| 2026-02-24 | Daniel Janney | Sell | $266.88 | 37,895 | $10.1M |
| 2026-02-24 | Daniel Janney | Sell | $268.34 | 13,825 | $3.7M |
| 2026-02-19 | Dino A Rossi | Sell | $261.41 | 18,950 | $5.0M |
| 2026-02-09 | Kathryn Romano | Sell | $272.14 | 12,500 | $3.4M |
| 2025-12-04 | Suma Krishnan | Sell | $220.16 | 25,000 | $5.5M |
| 2025-07-16 | Suma Krishnan | Sell | $150.00 | 1,529 | $229,350 |
| 2025-07-16 | Suma Krishnan | Sell | $150.00 | 1,389 | $208,350 |
| 2025-07-15 | Suma Krishnan | Sell | $150.98 | 3,036 | $458,375 |
| 2025-07-15 | Suma Krishnan | Sell | $151.01 | 3,084 | $465,715 |
| 2025-07-14 | Suma Krishnan | Sell | $150.30 | 13,435 | $2.0M |
| 2025-07-14 | Suma Krishnan | Sell | $150.30 | 13,400 | $2.0M |
| 2025-07-10 | Suma Krishnan | Sell | $150.28 | 6,800 | $1.0M |
| 2025-07-10 | Suma Krishnan | Sell | $150.27 | 6,927 | $1.0M |
| 2025-07-09 | Suma Krishnan | Sell | $150.14 | 200 | $30,028 |
Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.
KRYS shares outstanding
Year-end shares outstanding, adjusted for splits.
Who owns KRYS
Institutional investors own 102.4% of Krystal Biotech's shares and insiders 10.66%. The largest holder is FMR Inc with 14.93% of the shares (4.4M), as of June 30, 2026. Among the top 20 institutions, 14 added shares and 4 reduced their stake in the latest filings. Short interest is 19.23% of the float, or 12.53 days of average trading volume. The share count rose 600.5% since 2016.
Related: KRYS analyst forecast, KRYS key metrics. See the KRYS stock overview for the latest quote and news.
KRYS ownership FAQ
Who owns the most Krystal Biotech stock?
The largest shareholders of Krystal Biotech are FMR Inc (14.93%), BlackRock Inc (14.13%), venBio Select Advisor LLC (9.76%), Vanguard Portfolio Management, LLC (5.32%), State Street Corp (4.56%).
What percentage of Krystal Biotech is owned by institutions?
Institutions hold 102.4% of Krystal Biotech's shares outstanding; insiders hold 10.66%.
Which funds own Krystal Biotech?
The largest fund holders of Krystal Biotech are Fidelity Select Biotechnology (6.09%), iShares Core S&P Mid-Cap ETF (3.21%), Vanguard MStar Total Stk Mkt Idx Invest (3.01%), Fidelity Growth Company Fund (2.76%), American Funds SMALLCAP World A (2.54%).
What is Krystal Biotech's short interest?
3.5M shares of Krystal Biotech were sold short, 19.23% of the float; at the average daily volume it would take 12.53 days to cover.
Are insiders buying or selling Krystal Biotech?
Of the latest 19 reported insider transactions in Krystal Biotech (since July 9, 2025), 0 were purchases and 19 were sales.
How many shares of Krystal Biotech are outstanding?
Krystal Biotech has 29.6M shares outstanding, of which 23.6M are in the public float.